Mitophagy dysfunction in autosomal recessive Parkinson’s disease: is it the whole story?

Dr Olga Corti is Research Director at Institut National de la Santé et de la Recherche Médicale (Inserm) and co-leader of the team “Molecular pathophysiology of PD” at the Paris Brain Institute (ICM, institutducerveau-icm.org/en/team/team-corti-corvol). She has a long-standing interest in Parkinson’s Disease (PD) pathomechanisms, with a focus on familial PD forms, particularly PRKN-linked PD. Her research combines complementary approaches of biochemistry and molecular and cellular biology with mouse models and patient-derived cells to investigate the impact of PD mutations on mitochondrial quality control and function, cellular vulnerability to stress and innate immunity.