OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The widespread adoption of selective serotonin inhibitors (SSRIs) as first line pharmacological treatments in the management of clinical depression, transformed the landscape of drug therapy for this condition. SSRIs are safer and better tolerated than the tricyclic antidepressants (TCAs) which they replaced. However, they have limitations which may have placed a ceiling on expectations of first-line pharmacological treatment. Notable problems with SSRIs include induction of anxiety on treatment initiation, delayed onset of significant therapeutic effect, sexual dysfunction, sleep disturbance and overall modest efficacy. This talk will describe the development of SSRIs from TCAs and the pharmacological properties that might account for the superior efficacy of TCAs in some people with depression.
zoom.us/j/95199401096?pwd=ancrZ0U1b0RNVmlKL0tQdTQ5SzhLUT09
Meeting ID: 951 9940 1096
Passcode: 937384
