• Type: Seminar Series
• Organising department: Department of Biochemistry

Monday 27 April 2015 (1st Week, Trinity Term)

• 13:00 - Shaping mitotic chromosomes
  Dr Christian Haering (EMBL)

Monday 11 May 2015 (3rd Week, Trinity Term)

• 13:00 - Mechanism of protein transport into the endoplasmic reticulum
  Dr Ramanujan S. Hegde (MRC Laboratory of Molecular Biology)

Monday 22 June 2015 (9th Week, Trinity Term)

• 13:00 - Title TBC
  Professor Edith Heard, FRS (Professor College de France; Chair of Epigenetics and Cellular Memory. College de France and Director, Genetics and Developmental Biology Department, Institut Curie)

Friday 4 September 2015 (19th Week, Trinity Term)

• 11:00 - Unwrapping the function of histones during mitosis
  Professor Hironori Funabiki (Rockefeller University, New York)

Monday 7 September 2015 (20th Week, Trinity Term)

• 12:00 - Taste Processing in Drosophila
  Prof Kristin Scott (University of California, Berkeley)

Monday 21 September 2015 (-2nd Week, Michaelmas Term)

• 13:00 - 'How rotation is generated in the catalytic and membrane domains of F-TPases'
  Professor Sir John Walker, FRS, FMedSci (MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Cambridge)

Thursday 1 October 2015 (-1st Week, Michaelmas Term)

• 11:00 - Tackling Tough Targets in Malaria: Fragment-Based Drug Discovery and Vaccines Against Disordered Antigens
  Prof Ray Norton (Monash University, Australia)

Friday 2 October 2015 (-1st Week, Michaelmas Term)

• 01:25 - Graduate DPhil Symposium
  Various (See programme)

Monday 5 October 2015 (0th Week, Michaelmas Term)

• 13:00 - 'Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry'
  Professor Dr. Albert Heck (Professor of Biomolecular Mass Spectrometry and Proteomics, Utrecht University)

Monday 12 October 2015 (1st Week, Michaelmas Term)

• 13:00 - 'Looking at proteins in live cells with atomic resolution: from Science Fiction to Science Reality'
  Dr. Phil Selenko (Group Leader, In-cell NMR Spectroscopy, Leibniz Institute of Molecular Pharmacology, Berlin)
• 13:00 - Looking at proteins in live cells with atomic resolution: from Science Fiction to Science Reality
  Dr. Phil Selenko (Group Leader, In-cell NMR Spectroscopy, Leibniz Institute of Molecular Pharmacology, Berlin)

Monday 19 October 2015 (2nd Week, Michaelmas Term)

• 13:00 - "Salmonella intracellular persisters and TA modules"
  Dr. Sophie Helaine (MRC Research Fellow, Imperial College)

Monday 30 November 2015 (8th Week, Michaelmas Term)

• 13:00 - "Kinetochores: from microtubule attachment to spindle assembly checkpoint signalling"
  Professor Dr. Andrea Musacchio (Director of the Department of Mechanistic Cell Biology at the Max-Planck Institute of Molecular Physiology in Dortmund, Germany)

Monday 14 December 2015 (10th Week, Michaelmas Term)

• 13:00 - "Staphylococcus aureus - A Super Bug! "
  Professor Simon Foster (Professor of Molecular Microbiology, University of Sheffield)

Monday 25 April 2016 (1st Week, Trinity Term)

• 13:00 - O-GlcNAc signalling in development and disease
  Professor Daan van Aalten, FRSE (Wellcome Trust Senior Fellow, MRC Protein Phosphorylation Unit and Division of Molecular Microbiology, University of Dundee)

Monday 23 May 2016 (5th Week, Trinity Term)

• 13:00 - D-Peptide Therapeutics: Empowering Nature’s Fragile Warriors
  Michael S. Kay, M.D., Ph.D. (University of Utah)

Thursday 23 June 2016 (9th Week, Trinity Term)

• 16:00 - Writing for success: positioning and engaging in the publication jungle
  Maria Cerrato Lara (Oxford Brookes University)

Friday 24 June 2016 (9th Week, Trinity Term)

• 11:00 - "Understanding the molecular logic of Adhesion GPCRs in mechanosensation"
  Professor Tobias Langenhan (University of Wuerzburg)

Tuesday 28 June 2016 (10th Week, Trinity Term)

• 11:00 - "The PCGF6-PRC1 complex suppresses premature activation of meiosis and germ cell related genes in ES cells"
  Professor Haruhiko Koseki (Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan)

Tuesday 5 July 2016 (11th Week, Trinity Term)

• 14:00 - Proteomics technologies and their application in biomedical research
  Prof. Dr. Matthias Mann (Director Dept. Proteomics and Signal Transduction, MPI, Germany)

Thursday 7 July 2016 (11th Week, Trinity Term)

• 13:00 - "Intrinsic disorder controls the function of p53 and other cancer-associated IDPs"
  Gary Daughdrill (University of South Florida)

Monday 15 August 2016 (17th Week, Trinity Term)

• 15:00 - “Towards a structural understanding of dual-pumping membrane-integral pyrophosphatases”
  Dr Nita Shah (Astbury Centre for Structural Molecular Biology, University of Leeds)

Wednesday 24 August 2016 (18th Week, Trinity Term)

• 14:00 - Cohesin in motion: single molecule imaging of the human cohesin complex on DNA
  TBA

Friday 2 September 2016 (19th Week, Trinity Term)

• 11:00 - Multi-scale modeling of chromosomal DNA from the base pair to the genome
  Dr Andrew Spakowitz (Stanford University)

Monday 19 September 2016 (-2nd Week, Michaelmas Term)

• 11:00 - Ess1: Traffic Cop of the Transcription Cycle
  Steven Hanes (SUNY-Upstate Medical University)

Monday 17 October 2016 (2nd Week, Michaelmas Term)

• 13:00 - Gene regulation in chromatin
  Dr. Dirk Schübeler (Senior Group Leader, Friedrich Miescher Institute for Biomedical Research, Basel)

Tuesday 15 November 2016 (6th Week, Michaelmas Term)

• 09:30 - Special D. Phil Thesis Seminar: Probing the cohesin loading reaction using forward genetics and quantitative ChIP-seq
  TBA

Monday 5 December 2016 (9th Week, Michaelmas Term)

• 13:00 - Molecular Mechanisms involved in the Regulation of Appetite and Weight
  Professor Sadaf Farooqi PhD, FRCP, FMedSci (WT Senior Clinical Fellow and Professor of Metabolism and Medicine, University of Cambridge Metabolic Research Laboratories, Cambridge)

Thursday 8 December 2016 (9th Week, Michaelmas Term)

• 13:00 - Regulatory feedback from nascent RNA to transcription and chromatin modification
  TBA

Monday 9 January 2017 (0th Week, Hilary Term)

• 13:00 - Understanding the function and evolution of regulatory protein-RNA complexes
  Professor Jernej Ule (Professor of Molecular Neuroscience, The Francis Crick Institute, Department of Molecular Neuroscience, UCL Institute of Neurology, London)

Wednesday 11 January 2017 (0th Week, Hilary Term)

• 11:00 - New insight into the structure, function and dynamic of bacterial cell divisiion
  Professor Jie Xiao (John Hopkins University, Baltimore, USA)
• 12:00 - Kinetic UV cross-linking and analyses of cDNAs (xCRAC) reveals high-resolution dynamics of protein-RNA interactions in vivo
  Sander Granneman (Centre for Synthetic and Systems Biology (SynthSys), University of Edinburgh)

Thursday 12 January 2017 (0th Week, Hilary Term)

• 15:30 - The molecular mechanism and functional significance of GPS auto-proteolysis of adhesion-GPCRs: stories of EMR2/ADGRE2 and GPR56/ADGRG1
  Prof. Hsi-Hsien Lin (Chang Gung University, Taiwan)

Monday 16 January 2017 (1st Week, Hilary Term)

• 13:00 - "Gams to go: establishing and exploiting experimentally inducible sexual development in a malaria parasite"
  Professor A.P. Waters (Professor of Molecular and Developmental Parasitology, Wellcome Trust Principal Research Fellow, Director, Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow)

Friday 20 January 2017 (1st Week, Hilary Term)

• 12:00 - Early developmental program shapes colony morphology in bacteria
  Gideon Mamou (Hebrew University of Jerusalem, Israel)

Monday 6 February 2017 (4th Week, Hilary Term)

• 13:00 - Mitotic Checkpoint Kinases in Cancer Development and Treatment
  Prof. Dr. Rene H. Medema (Director of Research, Chairman Board of Directors, The Netherlands Cancer Institute, Amsterdam)

Thursday 30 March 2017 (11th Week, Hilary Term)

• 11:00 - Bacterial lipid trafficking and outer membrane homeostatis
  Shu-Sin Chng (National University of Singapore)

Monday 3 April 2017 (-2nd Week, Trinity Term)

• 13:00 - A new rationale for TF paralog evolution, expression and function
  Professor Matthias Merkenschlager (Lymphocyte Development Group, MRC Clinical Sciences Centre, London)

Tuesday 2 May 2017 (2nd Week, Trinity Term)

• 11:00 - “The way is the goal: recognition and targeting of proteins by the Sec translocation machinery in bacteria”
  Dr Damon Huber (University of Birmingham)

Wednesday 10 May 2017 (3rd Week, Trinity Term)

• 13:00 - Mechanics of the mitotic chromosome surface
  Dr. Daniel Wolfram Gerlich (Senior Research Group Leader, IMBA, Austria)

Monday 15 May 2017 (4th Week, Trinity Term)

• 16:00 - "ADP-ribosylation Site Identification: Discovery from Cancer to Virus"
  Professor Anthony Leung (MBiochem, Oxon) (John Hopkins University, Baltimore, USA)

Monday 12 June 2017 (8th Week, Trinity Term)

• 13:00 - Establishment and Maintenance of Specialised Chromatin Domains
  Professor Robin Allshire (Professor of Chromosome Biology, Wellcome Trust Centre for Cell Biology, University of Edinburgh)

Monday 3 July 2017 (11th Week, Trinity Term)

• 13:00 - Plasticity of neural circuits, from development to function
  Dr. Arantza Barrios (Research Associate, University College London)

Friday 29 September 2017 (-1st Week, Michaelmas Term)

• 12:00 - 'From single molecules to single cells: Imaging nucleic acid enzymes at work'
  Professor David Rueda (Imperial College London)
• 13:25 - DPhil Symposium
  Various Speakers

Monday 23 October 2017 (3rd Week, Michaelmas Term)

• 13:00 - Antisense transcription and epigenetic switching: lessons from FLC
  Professor Dame Caroline Dean (Project Leader, John Innes Centre, Norwich)

Monday 30 October 2017 (4th Week, Michaelmas Term)

• 17:00 - Evolutionary dynamics in the fungal symmetry breaking network
  Please note change of time: now at 5pm
  Dr. Liedewij Laan (Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, The Netherlands)

Monday 22 January 2018 (2nd Week, Hilary Term)

• 13:00 - Lights, Camera, Action! Antimalarial drug discovery using a microscope
  Professor Jake Baum (Professor of Cell Biology and Infectious Diseases, Imperial College London)

Monday 12 March 2018 (9th Week, Hilary Term)

• 13:00 - Single cell Hi-C and single molecule imaging to study nuclear architecture
  Professor Ernest Laue (Professor of Structural Biology, Department of Biochemistry, University of Cambridge)

Monday 30 April 2018 (2nd Week, Trinity Term)

• 13:00 - 'The remote control of gene expression'
  Professor Wendy Bickmore, FRS, FMedSci (Director: MRC Human Genetics Unit, IGMM, University of Edinburgh)

Monday 11 June 2018 (8th Week, Trinity Term)

• 13:00 - Cellular responses to DNA damage: translating molecular insights towards new cancer therapies
  Professor Steve Jackson, PhD, FRS, FMedSci (Frederick James Quick Professor of Biology, The Gurdon Institute, Cambridge)

Monday 2 July 2018 (11th Week, Trinity Term)

• 13:00 - Mitosis, genome stability and cancer chemotherapy
  Professor Stephen Taylor (Leech Professor of Pharmacology, Manchester Cancer Research Centre, University of Manchester)

Thursday 27 September 2018 (-1st Week, Michaelmas Term)

• 08:30 - Graduate Student Induction
  Various Speakers

Friday 28 September 2018 (-1st Week, Michaelmas Term)

• 13:30 - DPhil Symposium
  Various Speakers

Tuesday 24 September 2019 (-2nd Week, Michaelmas Term)

• 14:00 - Regulation of the DNA interstrand crosslink repair throught FANCD2 phosphorylation
  Marian Kupculak (Cell Biology, Development and Genetics,University of Oxford)
• 14:30 - Expanding the utility of peptide for dual function in purification and conjugation
  Irsyad Khairil Anuar (Cell Biology, Development and Genetics, Department of Biochemistry, University of Oxford)
• 15:00 - Revealing Secrets Hiding in Plain Sight: Advances in Multi-scale Multi-modal Imaging
  Mark H. Ellisman (Distinguished Professor of Neurosciences; Director, the National Center for Microscopy and Imaging Research (NCMIR), UC San Diego)

Tuesday 15 October 2019 (1st Week, Michaelmas Term)

• 10:00 - Versatile Tools Towards Real-time, Single- molecule and Single-Cell Biology
  Dr. Aida Llauró-Portell (LUMICKS)

Monday 24 May 2021 (5th Week, Trinity Term)

• 13:00 - "Replication and Repair: the faces of BRCA1"
  Professor Jo Morris PhD BSc (Professor of Molecular Genetics, Institute of Cancer and Genomic Sciences, University of Birmingham)

Monday 21 November 2022 (7th Week, Michaelmas Term)

• 13:00 - Of yeast and Man: Kinetochore Structures and Function
  Stanislau Yatskevich (LMB, Cambridge)

Tuesday 7 March 2023 (8th Week, Hilary Term)

• 15:30 - The physiological purpose for DNA repair in us - from gin and tonics to formalin pots
  Prof. K.J. Patel (MRC Weatherall Institute of Molecular Medicine)

Thursday 9 March 2023 (8th Week, Hilary Term)

• 15:00 - Understanding the mechanism and regulation of Eukaryotic DNA replication
  Dr. John Diffley, FMedSci, FRS (Associate Research Director, The Francis Crick Institute)

Thursday 30 November 2023 (8th Week, Michaelmas Term)

• 14:00 - Activation of an origin of replication visualised by cryo-EM
  Alessandro Costa (The Francis Crick Institute)

Monday 22 April 2024 (1st Week, Trinity Term)

• 13:00 - "Controlling Aurora-A kinase functions in mitosis and cancer"
  Professor Richard Bayliss (Professor of Molecular Medicine, The Astbury Centre for Structural Molecular Biology, University of Leeds)

Monday 29 April 2024 (2nd Week, Trinity Term)

• 13:00 - 'Targeting DNA methyltransferases to chromatin: a tale of two N- terminal regions’
  Dr. Marcus Wilson (Henry Dale Fellow / Academic Lead cryo-EM Facility, Wellcome Centre for Cell Biology, University of Edinburgh)