BEGIN:VCALENDAR
VERSION:2.0
PRODID:talks.ox.ac.uk
BEGIN:VEVENT
SUMMARY:T cell immunity begins with TCR allosteric activation - Professor 
 Oreste Acuto (University of Oxford )
DTSTART;VALUE=DATE-TIME:20191209T120000Z
DTEND;VALUE=DATE-TIME:20191209T130000Z
UID:https://talks.ox.ac.uk/talks/id/f23edde3-2d7a-49a0-859f-0183a0ffcfbc/
DESCRIPTION:T cell-dependent immunity commences with T-cell antigen recept
 or (TCR-CD3) signalling. TCR-CD3 features unique ligand recognition\, sign
 alling modalities and convoluted quaternary structure\, diverging consider
 ably from “classic”\, evolutionary ancient membrane receptors of simpl
 er molecular design and univocal relationship to ligands. TCR-CD3 recognis
 es with exceptional sensorial and discriminatory ability antigens of varyi
 ng structure\, quantity and detection context. Given such a complexity\, i
 t is perhaps unsurprising that controversy exists on how TCR-CD3 works. I 
 will report new data suggesting an allosteric mechanism by which TCR-CD3 t
 ransmits signals across the plasma membrane that should improve our unders
 tanding of how T cell activation begins.\nSpeakers:\nProfessor Oreste Acut
 o (University of Oxford )
LOCATION:Kennedy Institute of Rheumatology (Bernard Sunley Lecture Theatre
 )\, Headington OX3 7FY
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/f23edde3-2d7a-49a0-859f-0183a0ffcfbc/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:T cell immunity begins with TCR allosteric activation - P
 rofessor Oreste Acuto (University of Oxford )
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Spatial and dynamic control of T cell activation - Prof Bjorn Lill
 emeier (Nomis Center for Immunobiology and Microbial Pathogenesis  Waitt A
 dvanced Biophotonics Center The Salk Institute)
DTSTART;VALUE=DATE-TIME:20160913T150000
DTEND;VALUE=DATE-TIME:20160913T160000
UID:https://talks.ox.ac.uk/talks/id/6d112205-2fa8-4d32-be68-4144ccec9c2a/
DESCRIPTION:\nSpeakers:\nProf Bjorn Lillemeier (Nomis Center for Immunobio
 logy and Microbial Pathogenesis  Waitt Advanced Biophotonics Center The Sa
 lk Institute)
LOCATION:Sir William Dunn School of Pathology (EPA Seminar room)\, South P
 arks Road OX1 3RE
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/6d112205-2fa8-4d32-be68-4144ccec9c2a/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Spatial and dynamic control of T cell activation - Prof B
 jorn Lillemeier (Nomis Center for Immunobiology and Microbial Pathogenesis
   Waitt Advanced Biophotonics Center The Salk Institute)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Themis and PKCeta in regulation of TCR signaling and Treg activity
  - Prof Nicholas R J Gascoigne (Dept of Microbiology\, National University
  of Singapore)
DTSTART;VALUE=DATE-TIME:20150622T140000
DTEND;VALUE=DATE-TIME:20150622T150000
UID:https://talks.ox.ac.uk/talks/id/4d6742f6-115b-4a96-98cb-d4a8ac1b0c14/
DESCRIPTION:\nStatus: This talk is in preparation - details may change\n\n
 Speakers:\nProf Nicholas R J Gascoigne (Dept of Microbiology\, National Un
 iversity of Singapore)
LOCATION:Sir William Dunn School of Pathology (EPA Seminar Room)\, South P
 arks Road OX1 3RE
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/4d6742f6-115b-4a96-98cb-d4a8ac1b0c14/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Themis and PKCeta in regulation of TCR signaling and Treg
  activity - Prof Nicholas R J Gascoigne (Dept of Microbiology\, National U
 niversity of Singapore)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:How to hit HIV where it hurts   - Professor Arup K Chakraborty (De
 partments of Chemical Engineering\, Physics\, Chemistry\, and Biological E
 ngineering\, Institute for Medical Engineering and Science\, MIT)
DTSTART;VALUE=DATE-TIME:20150619T140000
DTEND;VALUE=DATE-TIME:20150619T150000
UID:https://talks.ox.ac.uk/talks/id/f68f4971-7979-42d1-8163-e27b627b2f3e/
DESCRIPTION:\nSpeakers:\nProfessor Arup K Chakraborty (Departments of Chem
 ical Engineering\, Physics\, Chemistry\, and Biological Engineering\, Inst
 itute for Medical Engineering and Science\, MIT)
LOCATION:Medical Sciences Teaching Centre (Lecture Theatre)\, off South Pa
 rks Road OX1 3PL
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/f68f4971-7979-42d1-8163-e27b627b2f3e/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:How to hit HIV where it hurts   - Professor Arup K Chakra
 borty (Departments of Chemical Engineering\, Physics\, Chemistry\, and Bio
 logical Engineering\, Institute for Medical Engineering and Science\, MIT)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
END:VCALENDAR