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SUMMARY:New genomic technologies to deconstruct and control cell identity 
 - Associate Professor Samantha Morris (Washington University School of Med
 icine)
DTSTART;VALUE=DATE-TIME:20230331T150000
DTEND;VALUE=DATE-TIME:20230331T160000
UID:https://talks.ox.ac.uk/talks/id/94655d92-781d-446a-8995-577d39aaad26/
DESCRIPTION:A mechanistic understanding of how cell identity is establishe
 d and maintained is fundamental to the precise engineering of cell fate. H
 ere\, I will present new genomic technologies developed by my lab to permi
 t single-cell lineage tracing throughout reprogram-ming\, accompanied by r
 ecording of TF-binding and chromatin accessibility profiling. Integrating 
 this information using our unique computational tools for interrogating ge
 ne regulatory networks delivers a systems-level understanding of how cell 
 identity can be manipulated via lineage reprogramming. We also apply these
  methods to understand how cell identity is naturally programmed during di
 fferentiation and development. The deconstruction of cell identity via the
 se approaches supports precision engineering of cell fate. \nSpeakers:\nAs
 sociate Professor Samantha Morris (Washington University School of Medicin
 e)
LOCATION:IMS-Tetsuya Nakamura Building (Seminar Rooms 1&2)\, Roosevelt Dr\
 , Headington OX3 7TY
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/94655d92-781d-446a-8995-577d39aaad26/
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DESCRIPTION:Talk:New genomic technologies to deconstruct and control cell 
 identity - Associate Professor Samantha Morris (Washington University Scho
 ol of Medicine)
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