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SUMMARY:Spatial Regulation Of Nutrient Response Pathways - Prof Bernadette
  Carol (University of Bristol)
DTSTART;VALUE=DATE-TIME:20251031T130000Z
DTEND;VALUE=DATE-TIME:20251031T140000Z
UID:https://talks.ox.ac.uk/talks/id/03650221-f964-44cb-ae38-102874af4d53/
DESCRIPTION:I studied for my PhD at Imperial College London\, where I was 
 working on the regulation of cell-cell adhesion by small GTPases. My work 
 explored how nutrient starvation impacted the spatio-temporal activity of 
 these proteins\, an area which I have continued to focus on throughout my 
 career. My postdoctoral work at Newcastle University and now\, as a Wellco
 me-funded Research Fellow in the School of Biochemistry at University of B
 ristol\, is focused on understanding the molecular cell biology of the nut
 rient-responsive mTORC1-autophagy axis. The pro-growth mTORC1 pathway and 
 the degradative autophagy-lysosome pathway control the dynamic balance bet
 ween biosynthesis\, degradation and recycling to maintain cellular proteos
 tasis and homeostasis. We are studying the mechanisms controlling the spat
 ial regulation and activity of these processes and how rewiring of this eq
 uilibrium contributes to cellular senescence (a tumour suppressor mechanis
 m of cell cycle arrest).\nSpeakers:\nProf Bernadette Carol (University of 
 Bristol)
LOCATION:Medical Sciences Teaching Centre (Lecture Theatre)\, off South Pa
 rks Road OX1 3PL
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/03650221-f964-44cb-ae38-102874af4d53/
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DESCRIPTION:Talk:Spatial Regulation Of Nutrient Response Pathways - Prof B
 ernadette Carol (University of Bristol)
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