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SUMMARY:Neural Footprints of Cardiovascular Risk: Personalized Neuroimagin
 g and Potential for Precision Medicine - Sindhuja Govindarajan (University
  of Pennsylvania)
DTSTART;VALUE=DATE-TIME:20250402T120000
DTEND;VALUE=DATE-TIME:20250402T130000
UID:https://talks.ox.ac.uk/talks/id/5f589025-a978-430d-9387-4f68cf6f3491/
DESCRIPTION:Cardiovascular and metabolic risk factors (CVMs) pose a signif
 icant threat to brain health\, contributing to a substantial portion of de
 mentia cases. What if we could detect early signs of brain alterations cau
 sed by common health conditions like hypertension and diabetes in midlife\
 , well before cognitive symptoms appear? In this talk\, I will describe ho
 w leveraged large\, harmonized MRI datasets and machine learning to create
  in-silico severity markers to quantify the impact of CVMs on individual b
 rain MRIs. With these personalized markers\, we can potentially identify i
 ndividuals who are vulnerable to the cognitive effects of CVMs much earlie
 r than current methods allow\, opening a critical window for early interve
 ntion. These data-driven tools offer critical insights into the link betwe
 en heart health and brain health\, enabling us to identify at-risk individ
 uals and pave the way for precision medicine approaches to dementia preven
 tion.\n\nTeams link: https://www.win.ox.ac.uk/events/win_seminar_apr_2025 
 \nSpeakers:\nSindhuja Govindarajan (University of Pennsylvania)
LOCATION:FMRIB Centre (Cowey Room\, FMRIB Annexe)\, Headington OX3 9DU
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/5f589025-a978-430d-9387-4f68cf6f3491/
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DESCRIPTION:Talk:Neural Footprints of Cardiovascular Risk: Personalized Ne
 uroimaging and Potential for Precision Medicine - Sindhuja Govindarajan (U
 niversity of Pennsylvania)
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