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SUMMARY:Stem cell therapy for perinatal brain injuries  - Dr Yoshiaki Sato
  (Nagoya University Hospital)
DTSTART;VALUE=DATE-TIME:20231113T150000Z
DTEND;VALUE=DATE-TIME:20231113T160000Z
UID:https://talks.ox.ac.uk/talks/id/fefcf6a6-1ee6-4447-b7ff-252e5c3993c8/
DESCRIPTION:Despite the significant reduction in global neonatal mortality
  over the last 30 years\, there are still numerous intractable perinatal d
 iseases requiring novel therapies\, including perinatal hypoxic-ischemic e
 ncephalopathy (HIE). Stem cell therapy is expected to be a promising treat
 ment option for such diseases\, as it has several advantages\, such as the
  ability to replace injured cells\, regenerate on their own\, and produce 
 growth factors that induce therapeutic effects. Moreover\, stem cells can 
 migrate to where they are needed\, even when administered intravenously\, 
 and respond to the situation and location.\nWe are developing novel stem c
 ell-based therapies for various perinatal diseases\, focusing on HIE and b
 ronchopulmonary dysplasia. Regarding HIE\, we have conducted basic researc
 h on various types of stem cells\, such as neural stem/progenitor cells\, 
 umbilical cord blood cells\, and mesenchymal stem cells derived from vario
 us tissues. Among these stem cells\, we have proceeded to a clinical trial
  with multilineage-differentiating stress-enduring cells. \nAdditionally\,
  we are focusing on the treatment of neurological symptoms in the chronic 
 phase\, such as cerebral palsy\, and are planning a clinical trial with st
 em cells from human exfoliated deciduous teeth (SHED)\, which have demonst
 rated treatment effects in the chronic phase after HIE by animal studies.\
 nIn this presentation\, I will talk about basic\, translational\, and clin
 ical studies on HIE and the potential of stem cell therapy as a novel trea
 tment for perinatal brain injuries.\n\n\nSpeakers:\nDr Yoshiaki Sato (Nago
 ya University Hospital)
LOCATION:Sherrington Library\, off Parks Road OX1 3PT
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/fefcf6a6-1ee6-4447-b7ff-252e5c3993c8/
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DESCRIPTION:Talk:Stem cell therapy for perinatal brain injuries  - Dr Yosh
 iaki Sato (Nagoya University Hospital)
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