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SUMMARY:Adaptation to Natural Input Statistics: a Key to Dendritic Computa
 tion and Plasticity - Dr Máté Lengyet (University of Cambridge)
DTSTART;VALUE=DATE-TIME:20151124T120000Z
DTEND;VALUE=DATE-TIME:20151124T130000Z
UID:https://talks.ox.ac.uk/talks/id/5c927ce0-81ff-4d10-b730-52dfaab5aaa9/
DESCRIPTION:\nSpeakers:\nDr Máté Lengyet (University of Cambridge)
LOCATION:Old Indian Institute\, Broad Street\, Oxford
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/5c927ce0-81ff-4d10-b730-52dfaab5aaa9/
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DESCRIPTION:Talk:Adaptation to Natural Input Statistics: a Key to Dendriti
 c Computation and Plasticity - Dr Máté Lengyet (University of Cambridge)
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SUMMARY:A Circuit Architecture for Angular Integration - Gaby Maimon (The 
 Rockefeller University)
DTSTART;VALUE=DATE-TIME:20170403T120000
DTEND;VALUE=DATE-TIME:20170403T130000
UID:https://talks.ox.ac.uk/talks/id/8d6b9478-19ba-479a-8a2b-5bcbdd4209b6/
DESCRIPTION:Mammalian brains store and update quantitative internal variab
 les. Primates and rodents\, for example\, have an internal sense of whethe
 r they are 1 or 10 meters away from a landmark and whether a ripe fruit is
  twice or four times as appetizing as a less ripe counterpart. Such quanti
 tative internal signals are the basis of cognitive function\; however\, ou
 r understanding of how the brain stores and updates these variables remain
 s fragmentary. I will discuss imaging and perturbation experiments in teth
 ered\, walking Drosophila whose goal is to determine how internal variable
 s are calculated and how they influence behavior. Specifically\, in the ce
 ntral complex a set of heading neurons have been described\, whose activit
 y tracks the fly’s orientation\, similar to head direction cells in rode
 nts. The circuit architecture that gives rise to these orientation trackin
 g properties remains unknown. I will describe a set of clockwise- and coun
 terclockwise-shifting neurons whose wiring and calcium dynamics provide a 
 means to rotate the heading system’s angular estimate over time. Shiftin
 g neurons are required for properly tracking the fly's movements in the da
 rk\, and their stimulation induces a rotation of the heading signal in the
  expected direction and by the expected amount. The central features of th
 is circuit are analogous to models proposed for head direction cells in ro
 dents and may thus inform how neural systems\, in general\, perform integr
 ation.\nSpeakers:\nGaby Maimon (The Rockefeller University)
LOCATION:The Oxford Martin School
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/8d6b9478-19ba-479a-8a2b-5bcbdd4209b6/
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DESCRIPTION:Talk:A Circuit Architecture for Angular Integration - Gaby Mai
 mon (The Rockefeller University)
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SUMMARY:Hunger-Driven Motivational State Competition - Michael Krashes (Na
 tional Institutes of Health (NIH))
DTSTART;VALUE=DATE-TIME:20170330T120000
DTEND;VALUE=DATE-TIME:20170330T130000
UID:https://talks.ox.ac.uk/talks/id/4b435d0b-d370-4dd0-8087-75a782dd032f/
DESCRIPTION:Goal-directed behaviors are sets of motor actions that direct 
 an animal toward an explicit target object\, an interaction that promotes 
 individual survival and/or maintains the species. Despite the necessity of
  motivated behaviors ranging from ingestive to reproductive to aggressive/
 defensive exploits\, an organism can only perform a single action at any g
 iven time\, highlighting the tremendous flexibility and speed with which t
 he brain can coordinate complex decision-making. We investigate the role d
 istinct levels of satiety play on shaping innate\, motivated drive states 
 as well as the subsets of neurons capable of perturbing innate behavioral 
 choice.\n\n\n\nSpeakers:\nMichael Krashes (National Institutes of Health (
 NIH))
LOCATION:Sherrington Library
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/4b435d0b-d370-4dd0-8087-75a782dd032f/
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DESCRIPTION:Talk:Hunger-Driven Motivational State Competition - Michael Kr
 ashes (National Institutes of Health (NIH))
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SUMMARY:Dissecting the Circuits and Algorithms That Process Visual Motion 
 - Thomas R Clandinin
DTSTART;VALUE=DATE-TIME:20170321T120000Z
DTEND;VALUE=DATE-TIME:20170321T130000Z
UID:https://talks.ox.ac.uk/talks/id/7973396a-8f87-4cae-bcaa-947729db8f9a/
DESCRIPTION:Peripheral visual circuits perform paradigmatic computations s
 uch as motion processing. However\, our understanding of the necessary and
  sufficient roles of individual cell types\, their interactions\, and the 
 molecules that underpin their specific activity patterns remains limited. 
 Our work combines genetic manipulations of both neural activity and molecu
 lar function with in vivo imaging of calcium and voltage signals to unrave
 l circuit mechanisms using the Drosophila visual system as a model. Our re
 sults reveal that the algorithms used to detect visual motion in flies and
  humans are fundamentally similar.\nSpeakers:\nThomas R Clandinin
LOCATION:The Old Martin School
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/7973396a-8f87-4cae-bcaa-947729db8f9a/
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DESCRIPTION:Talk:Dissecting the Circuits and Algorithms That Process Visua
 l Motion - Thomas R Clandinin
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