BEGIN:VCALENDAR VERSION:2.0 PRODID:talks.ox.ac.uk BEGIN:VEVENT SUMMARY:Dynamic Shielding and Allosteric Modulation of Erythropoietin by G lycosylation - Yuji Sugita (RIKEN PRI/R-CCS\, University of Tokyo) DTSTART;VALUE=DATE-TIME:20260306T110000Z DTEND;VALUE=DATE-TIME:20260306T120000Z UID:https://talks.ox.ac.uk/talks/id/5c8ffeab-3a86-4849-a244-40c93ab6eefc/ DESCRIPTION:\nSpeakers:\nYuji Sugita (RIKEN PRI/R-CCS\, University of Tok yo) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-138 Seminar Room 2)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5c8ffeab-3a86-4849-a244-40c93ab6eefc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Dynamic Shielding and Allosteric Modulation of Erythropoi etin by Glycosylation - Yuji Sugita (RIKEN PRI/R-CCS\, University of Toky o) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Cooling fast and slow: Characterising the effects of vitrification in cryo-EM and the subsequent recovery of equilibrium populations - Rober t Clark (University of Oxford) DTSTART;VALUE=DATE-TIME:20260226T140000Z DTEND;VALUE=DATE-TIME:20260226T150000Z UID:https://talks.ox.ac.uk/talks/id/9a4e4be6-13fd-4550-920b-b2e249a037b1/ DESCRIPTION:\nSpeakers:\nRobert Clark (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9a4e4be6-13fd-4550-920b-b2e249a037b1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Cooling fast and slow: Characterising the effects of vitr ification in cryo-EM and the subsequent recovery of equilibrium population s - Robert Clark (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:From Concept to Carrier: De Novo Design of PepT2-Transportable Car bapenem Antibiotics - Dr Jeffrey Pang (University of Oxford) DTSTART;VALUE=DATE-TIME:20260115T140000Z DTEND;VALUE=DATE-TIME:20260115T150000Z UID:https://talks.ox.ac.uk/talks/id/c6052f2d-bc99-4c7d-b4dc-34dedad499a0/ DESCRIPTION:\nSpeakers:\nDr Jeffrey Pang (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 40-091 Second Floor)\, of f South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c6052f2d-bc99-4c7d-b4dc-34dedad499a0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:From Concept to Carrier: De Novo Design of PepT2-Transpor table Carbapenem Antibiotics - Dr Jeffrey Pang (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260625T140000 DTEND;VALUE=DATE-TIME:20260625T150000 UID:https://talks.ox.ac.uk/talks/id/8b98a4af-dab1-4b9b-b3e2-ecf2a7e0e5da/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8b98a4af-dab1-4b9b-b3e2-ecf2a7e0e5da/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260618T140000 DTEND;VALUE=DATE-TIME:20260618T150000 UID:https://talks.ox.ac.uk/talks/id/fa1a25f1-0eee-4217-bdb4-fc78ec6c0839/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fa1a25f1-0eee-4217-bdb4-fc78ec6c0839/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260611T140000 DTEND;VALUE=DATE-TIME:20260611T150000 UID:https://talks.ox.ac.uk/talks/id/ad2a0cd4-8db4-4302-83f9-48b7c25e19dc/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ad2a0cd4-8db4-4302-83f9-48b7c25e19dc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260604T140000 DTEND;VALUE=DATE-TIME:20260604T150000 UID:https://talks.ox.ac.uk/talks/id/0bc8f09f-7edc-42cf-99fe-93393f000648/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/0bc8f09f-7edc-42cf-99fe-93393f000648/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260528T140000 DTEND;VALUE=DATE-TIME:20260528T150000 UID:https://talks.ox.ac.uk/talks/id/eea083e6-0da2-4947-985a-9661e2e493f5/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/eea083e6-0da2-4947-985a-9661e2e493f5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC - Aleksandr Kovalenko (University of Oxford) DTSTART;VALUE=DATE-TIME:20260521T140000 DTEND;VALUE=DATE-TIME:20260521T150000 UID:https://talks.ox.ac.uk/talks/id/570ae4c7-9aa2-4b70-9ce1-0455d569bea2/ DESCRIPTION:\nSpeakers:\nAleksandr Kovalenko (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/570ae4c7-9aa2-4b70-9ce1-0455d569bea2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC - Aleksandr Kovalenko (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260514T140000 DTEND;VALUE=DATE-TIME:20260514T150000 UID:https://talks.ox.ac.uk/talks/id/51fc72db-2945-45f5-b6ff-85f59e6b0fe4/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/51fc72db-2945-45f5-b6ff-85f59e6b0fe4/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC - Kyle Vaccaro (University of Oxford) DTSTART;VALUE=DATE-TIME:20260507T140000 DTEND;VALUE=DATE-TIME:20260507T150000 UID:https://talks.ox.ac.uk/talks/id/eda69341-5919-4ce5-a4ec-35a6c7db18d5/ DESCRIPTION:\nSpeakers:\nKyle Vaccaro (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/eda69341-5919-4ce5-a4ec-35a6c7db18d5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC - Kyle Vaccaro (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC - Eden Gage (University of Oxford) DTSTART;VALUE=DATE-TIME:20260430T140000 DTEND;VALUE=DATE-TIME:20260430T150000 UID:https://talks.ox.ac.uk/talks/id/f6dffdd1-a8ab-4df6-b92f-5efd6a2b8c0b/ DESCRIPTION:\nSpeakers:\nEden Gage (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (TBC)\, off South Parks Road OX 1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f6dffdd1-a8ab-4df6-b92f-5efd6a2b8c0b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC - Eden Gage (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260319T140000Z DTEND;VALUE=DATE-TIME:20260319T150000Z UID:https://talks.ox.ac.uk/talks/id/a355f335-2525-410a-b114-ec077fb9ed57/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a355f335-2525-410a-b114-ec077fb9ed57/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC - Mingyu Qin (University of Oxford) DTSTART;VALUE=DATE-TIME:20260312T140000Z DTEND;VALUE=DATE-TIME:20260312T150000Z UID:https://talks.ox.ac.uk/talks/id/19b4dc4f-6123-4e58-8534-59c34671415e/ DESCRIPTION:\nSpeakers:\nMingyu Qin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/19b4dc4f-6123-4e58-8534-59c34671415e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC - Mingyu Qin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20260219T140000Z DTEND;VALUE=DATE-TIME:20260219T150000Z UID:https://talks.ox.ac.uk/talks/id/dcedda87-c55c-4b43-8a45-78965c6f7d9e/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/dcedda87-c55c-4b43-8a45-78965c6f7d9e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Behaviour of FATP2 across multiple membrane scenarios - Dr Florenc ia Klein Rocha (University of Oxford) DTSTART;VALUE=DATE-TIME:20260212T140000Z DTEND;VALUE=DATE-TIME:20260212T150000Z UID:https://talks.ox.ac.uk/talks/id/e1256558-458c-49ec-bc5d-94c7a2f2b375/ DESCRIPTION:\nSpeakers:\nDr Florencia Klein Rocha (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e1256558-458c-49ec-bc5d-94c7a2f2b375/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Behaviour of FATP2 across multiple membrane scenarios - D r Florencia Klein Rocha (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Large scale simulations of the E. coli outer membrane - Dr Reza Ta landashti (University of Oxford) DTSTART;VALUE=DATE-TIME:20260205T140000Z DTEND;VALUE=DATE-TIME:20260205T150000Z UID:https://talks.ox.ac.uk/talks/id/82b2bcf3-85d9-40e9-97a3-15085d1adab9/ DESCRIPTION:\nSpeakers:\nDr Reza Talandashti (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/82b2bcf3-85d9-40e9-97a3-15085d1adab9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Large scale simulations of the E. coli outer membrane - D r Reza Talandashti (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:NeuralBind: Synthetic data augmentation for binding affinity predi ction via co-folding - Dr Wei-Tse Hsu (University of Oxford) DTSTART;VALUE=DATE-TIME:20260122T140000Z DTEND;VALUE=DATE-TIME:20260122T150000Z UID:https://talks.ox.ac.uk/talks/id/2fed9656-a177-476a-a484-610514532d8b/ DESCRIPTION:\nSpeakers:\nDr Wei-Tse Hsu (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2fed9656-a177-476a-a484-610514532d8b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:NeuralBind: Synthetic data augmentation for binding affin ity prediction via co-folding - Dr Wei-Tse Hsu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Sharing Biomolecular Simulations using FAIR Principles: MDDB and M emProtMD - Dr Charlotte Lynch (University of Oxford) DTSTART;VALUE=DATE-TIME:20251204T140000Z DTEND;VALUE=DATE-TIME:20251204T150000Z UID:https://talks.ox.ac.uk/talks/id/a28e78f0-8d88-4961-bd90-5d52c0411c13/ DESCRIPTION:\nSpeakers:\nDr Charlotte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-138 Seminar Room 2 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a28e78f0-8d88-4961-bd90-5d52c0411c13/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Sharing Biomolecular Simulations using FAIR Principles: M DDB and MemProtMD - Dr Charlotte Lynch (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Using an enhanced umbrella sampling workflow to describe novel gly cine receptor fenestrations - Bjarne Feddersen DTSTART;VALUE=DATE-TIME:20251127T140000Z DTEND;VALUE=DATE-TIME:20251127T150000Z UID:https://talks.ox.ac.uk/talks/id/35dc5936-905a-410c-9a01-430c4964dae7/ DESCRIPTION:\nSpeakers:\nBjarne Feddersen LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 40-091 Second Floor )\, o ff South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/35dc5936-905a-410c-9a01-430c4964dae7/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Using an enhanced umbrella sampling workflow to describe novel glycine receptor fenestrations - Bjarne Feddersen TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:autoAMP: Benchmarking the efficacy of PLM predicted antimicrobial peptides - Dr Iain Smith (University of Oxford) DTSTART;VALUE=DATE-TIME:20251120T140000Z DTEND;VALUE=DATE-TIME:20251120T150000Z UID:https://talks.ox.ac.uk/talks/id/c18c7202-6df8-44dc-9d3b-3ccd536bd977/ DESCRIPTION:\nSpeakers:\nDr Iain Smith (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c18c7202-6df8-44dc-9d3b-3ccd536bd977/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:autoAMP: Benchmarking the efficacy of PLM predicted antim icrobial peptides - Dr Iain Smith (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:A first-principles computational study of the proton coupled trans porter cystinosin - Dr Jonathan Colburn (University of Oxford) DTSTART;VALUE=DATE-TIME:20251106T140000Z DTEND;VALUE=DATE-TIME:20251106T150000Z UID:https://talks.ox.ac.uk/talks/id/6776dca4-d8d4-4801-8b1e-2044a9df6aa2/ DESCRIPTION:\nSpeakers:\nDr Jonathan Colburn (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6776dca4-d8d4-4801-8b1e-2044a9df6aa2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:A first-principles computational study of the proton coup led transporter cystinosin - Dr Jonathan Colburn (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Making It Stick: Designing Molecular Glues to Target Tuberculosis - Linda Phan (University of Oxford) DTSTART;VALUE=DATE-TIME:20251030T140000Z DTEND;VALUE=DATE-TIME:20251030T150000Z UID:https://talks.ox.ac.uk/talks/id/7042f35c-327e-42b0-9b01-6251b9e07918/ DESCRIPTION:\nSpeakers:\nLinda Phan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 20-026 Seminar Room 1 )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7042f35c-327e-42b0-9b01-6251b9e07918/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Making It Stick: Designing Molecular Glues to Target Tube rculosis - Linda Phan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational microbiology- what is it? - Professor Syma Khalid (U niversity of Oxford) DTSTART;VALUE=DATE-TIME:20251016T140000 DTEND;VALUE=DATE-TIME:20251016T150000 UID:https://talks.ox.ac.uk/talks/id/a183895a-4840-461b-9f1a-488c4d8677b1/ DESCRIPTION:\nSpeakers:\nProfessor Syma Khalid (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 40-091 Second Floor )\, o ff South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a183895a-4840-461b-9f1a-488c4d8677b1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational microbiology- what is it? - Professor Syma Khalid (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Membrane proteins - what can simulation tell us? - Professor Phil Biggin (Dept. of Biochemistry\, University of Oxford) DTSTART;VALUE=DATE-TIME:20251009T140000 DTEND;VALUE=DATE-TIME:20251009T150000 UID:https://talks.ox.ac.uk/talks/id/8bb05fc0-20e2-42d0-8f50-e8184e23f210/ DESCRIPTION:\nSpeakers:\nProfessor Phil Biggin (Dept. of Biochemistry\, Un iversity of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 40-091 Second Floor)\, of f South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8bb05fc0-20e2-42d0-8f50-e8184e23f210/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Membrane proteins - what can simulation tell us? - Profes sor Phil Biggin (Dept. of Biochemistry\, University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:PepT2: Mechanism of Proton-Coupled Oligopeptide Transport - Kyle V accaro (University of Oxford) DTSTART;VALUE=DATE-TIME:20250626T140000 DTEND;VALUE=DATE-TIME:20250626T150000 UID:https://talks.ox.ac.uk/talks/id/079aeecd-713d-4ab1-9644-684c9921305e/ DESCRIPTION:\nSpeakers:\nKyle Vaccaro (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/079aeecd-713d-4ab1-9644-684c9921305e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:PepT2: Mechanism of Proton-Coupled Oligopeptide Transport - Kyle Vaccaro (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Characterising the Impact of Glycosylation on the Structure of the Campylobacter jejuni Multidrug Efflux Pump - Dr Astrid Brandner (Univers ity of Oxford) DTSTART;VALUE=DATE-TIME:20250612T140000 DTEND;VALUE=DATE-TIME:20250612T150000 UID:https://talks.ox.ac.uk/talks/id/735bcd7b-282d-45ae-a118-d64129e622f4/ DESCRIPTION:\nSpeakers:\nDr Astrid Brandner (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/735bcd7b-282d-45ae-a118-d64129e622f4/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Characterising the Impact of Glycosylation on the Structu re of the Campylobacter jejuni Multidrug Efflux Pump - Dr Astrid Brandner (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Benchmarking Inverse Folding Models for Antibody CDR Sequence Desi gn - Dr Jeffery Pang (University of Oxford) DTSTART;VALUE=DATE-TIME:20250605T140000 DTEND;VALUE=DATE-TIME:20250605T150000 UID:https://talks.ox.ac.uk/talks/id/acace5df-c8dc-425b-9f09-577d82dc434f/ DESCRIPTION:\nSpeakers:\nDr Jeffery Pang (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (room 40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/acace5df-c8dc-425b-9f09-577d82dc434f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Benchmarking Inverse Folding Models for Antibody CDR Sequ ence Design - Dr Jeffery Pang (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Structural and Functional Insights into a Highly Atypical Syntheti c Chloride Channel - Eden Gage (University of Oxford) DTSTART;VALUE=DATE-TIME:20250529T140000 DTEND;VALUE=DATE-TIME:20250529T150000 UID:https://talks.ox.ac.uk/talks/id/656147f6-60df-40a4-bbbd-83938f449fca/ DESCRIPTION:\nSpeakers:\nEden Gage (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026) )\, of f South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/656147f6-60df-40a4-bbbd-83938f449fca/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Structural and Functional Insights into a Highly Atypical Synthetic Chloride Channel - Eden Gage (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20250522T150000 DTEND;VALUE=DATE-TIME:20250522T160000 UID:https://talks.ox.ac.uk/talks/id/3b2dab1e-4b30-4a28-8e32-825d7c6d229f/ DESCRIPTION:\nSpeakers:\nDr Jeffrey Pang (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3b2dab1e-4b30-4a28-8e32-825d7c6d229f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Integrative modeling of glycoproteins - Dr Mateusz Sikora (Malopo lska Centre of Biotechnology\, Krakow\, Poland) DTSTART;VALUE=DATE-TIME:20250220T140000Z DTEND;VALUE=DATE-TIME:20250220T150000Z UID:https://talks.ox.ac.uk/talks/id/309e6190-0aac-4531-9d2e-02b2f3f30924/ DESCRIPTION:Glycans\, complex sugars covalently attached to proteins\, pla y crucial roles in protein stability and function\, participate in "self" recognition\, and modulate protein-protein interactions. Unlike proteins\, glycans typically do not form secondary structures and remain highly mobi le\, posing challenges for traditional structural biology techniques. This high mobility\, coupled with glycan heterogeneity\, complicates the eluci dation of complete glycoprotein structures and hinders research on the rol e of glycans in protein function. Although computer simulations can help a ddress these challenges\, they often require millions of hours on speciali zed supercomputers\, highlighting the need for approximate methods that ca n be integrated into protein-solving pipelines.\n\nTo overcome these obsta cles\, we developed a simplified\, open-source method for rapidly predicti ng the span and shape of glycans with minimal computing power. Using this approach\, we can accurately predict SARS-CoV-2 spike protein epitopes tha t are not shielded by glycans\, as well as assess the impact of glycans on protein flexibility. We also demonstrate that this method can be integrat ed with structural biology methods and glycoproteomics pipelines\, offerin g a comprehensive tool for glycoprotein analysis.\n\n1. B Turoňová\, M S ikora\, C Schürmann\, WJH Hagen\, S Welsch et al.\, In situ structural an alysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. S cience\, 370(6513) 2020\n\n2. R Zhu\, D Canena\, M Sikora\, M Klausberger\ , H Seferovic\, et al.\, Force-tuned avidity of spike variant-ACE2 interac tions viewed on the single-molecule level\; Nat Comm\, 13(7926) 2022\n\n3. M Sikora\, S von Bülow\, FEC Blanc\, M Gecht\, R Covino\, G Hummer. Comp utational epitope map of SARS-CoV-2 spike protein. PLoS computational biol ogy\, 17(4) 2021\n\n4. Tsai YX\, Chang NE\, Reuter K\, Chang HT\, Yang TJ\ , von Bülow S\, Sehrawat V\, Zerrouki N\, Tuffery M\, Gecht M\, Grothaus IL\, Colombi Ciacchi L\, Wang YS\, Hsu MF\, Khoo KH\, Hummer G\, Hsu SD\, Hanus C\, Sikora M. Rapid simulation of glycoprotein structures by graftin g and steric exclusion of glycan conformer libraries. Cell\, 187(5):1296-1 311.e26.\nSpeakers:\nDr Mateusz Sikora (Malopolska Centre of Biotechnology \, Krakow\, Poland) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026) )\, of f South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/309e6190-0aac-4531-9d2e-02b2f3f30924/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Integrative modeling of glycoproteins - Dr Mateusz Sikor a (Malopolska Centre of Biotechnology\, Krakow\, Poland) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Developing Biomolecular Simulation Databases: MDDB and MemProtMD - Dr Charlotte Lynch (University of Oxford) DTSTART;VALUE=DATE-TIME:20250515T140000 DTEND;VALUE=DATE-TIME:20250515T150000 UID:https://talks.ox.ac.uk/talks/id/17bdaa49-4c6d-4d9d-90fd-b4b589e9d1ca/ DESCRIPTION:\nSpeakers:\nDr Charlotte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (room 40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/17bdaa49-4c6d-4d9d-90fd-b4b589e9d1ca/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Developing Biomolecular Simulation Databases: MDDB and Me mProtMD - Dr Charlotte Lynch (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II talks - Ronan Holland (University of Oxford)\, Thomas Doug las (University of Oxford) DTSTART;VALUE=DATE-TIME:20250508T140000 DTEND;VALUE=DATE-TIME:20250508T150000 UID:https://talks.ox.ac.uk/talks/id/4b458cc6-1c91-45ca-a7f5-b4fc29ca3b6b/ DESCRIPTION:Ronan holland "Elucidating Cell Wall Structure and Behaviour u sing CG MD"\n \nThomas Douglas "Garbage in\, Garbage out? The impact of tr aining data on machine learning based scoring functions"\nSpeakers:\nRonan Holland (University of Oxford)\, Thomas Douglas (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026) )\, of f South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4b458cc6-1c91-45ca-a7f5-b4fc29ca3b6b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II talks - Ronan Holland (University of Oxford)\, Th omas Douglas (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II talks - Lola Bell (University of Oxford)\, Antonia-Florina Panescu (University of Oxford) DTSTART;VALUE=DATE-TIME:20250501T140000 DTEND;VALUE=DATE-TIME:20250501T150000 UID:https://talks.ox.ac.uk/talks/id/2c6e3486-609f-45c1-8d5e-68f854bb6002/ DESCRIPTION:Today we will hear from:\n\nLola Bell "Flipping the switch: Un derstanding the structural mechanism of agonist-mediated ion selectivity i n TPC2"\n\nAntonia-Florina Panescu "Computational Investigation of SLC15A3 via Molecular and Quantum Mechanics Simulations" \nSpeakers:\nLola Bell (University of Oxford)\, Antonia-Florina Panescu (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2c6e3486-609f-45c1-8d5e-68f854bb6002/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II talks - Lola Bell (University of Oxford)\, Antoni a-Florina Panescu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II talks - Ronan Holland (University of Oxford)\, Kate Mulhol land (University of Oxford) DTSTART;VALUE=DATE-TIME:20250424T140000 DTEND;VALUE=DATE-TIME:20250424T150000 UID:https://talks.ox.ac.uk/talks/id/1f445939-2934-47b8-b669-8dc54d92b6c9/ DESCRIPTION:Ronan Holland "Elucidating Cell Wall Structure and Behaviour u sing CG MD"\n\nKate Mulholland "Comparison of coarse-grained models to inv estigate Magainin 2 behaviour in the presence of a lipid bilayer"\nSpeaker s:\nRonan Holland (University of Oxford)\, Kate Mulholland (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 (20-026) )\, of f South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1f445939-2934-47b8-b669-8dc54d92b6c9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II talks - Ronan Holland (University of Oxford)\, Ka te Mulholland (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular dynamics of RNA translocation through a nanopore - Zeph yr Ford (University of Oxford) DTSTART;VALUE=DATE-TIME:20250320T140000Z DTEND;VALUE=DATE-TIME:20250320T150000Z UID:https://talks.ox.ac.uk/talks/id/ef9609f6-8e2b-4bdf-b1e1-daf182d205eb/ DESCRIPTION:\nSpeakers:\nZephyr Ford (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (DCHB 40-091\, 2nd floor)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ef9609f6-8e2b-4bdf-b1e1-daf182d205eb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular dynamics of RNA translocation through a nanopor e - Zephyr Ford (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Mechanism of lipid uptake and release by STARD lipid transfer prot eins DTSTART;VALUE=DATE-TIME:20250313T143000Z DTEND;VALUE=DATE-TIME:20250313T153000Z UID:https://talks.ox.ac.uk/talks/id/025c969a-806a-4ab4-a37e-d82fc4b709fd/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/025c969a-806a-4ab4-a37e-d82fc4b709fd/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Mechanism of lipid uptake and release by STARD lipid tran sfer proteins TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Optimizing multivalent dendrimers as potential antibiotic agents - Mingyu Qin (University of Oxford) DTSTART;VALUE=DATE-TIME:20250227T143000Z DTEND;VALUE=DATE-TIME:20250227T153000Z UID:https://talks.ox.ac.uk/talks/id/bfd5caab-4442-4dcc-8cff-2e8c82d7613e/ DESCRIPTION:\nSpeakers:\nMingyu Qin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/bfd5caab-4442-4dcc-8cff-2e8c82d7613e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Optimizing multivalent dendrimers as potential antibiotic agents - Mingyu Qin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Annual BPS meeting talks - Professor Syma Khalid (University of Ox ford)\, Dr Jonathan Colburn (University of Oxford)\, Cyril Schroeder (Univ ersity of Oxford) DTSTART;VALUE=DATE-TIME:20250206T143000Z DTEND;VALUE=DATE-TIME:20250206T153000Z UID:https://talks.ox.ac.uk/talks/id/656b20b7-bc79-4432-a16f-fd2dfbf38a63/ DESCRIPTION:Three talk will be featured in this meeting:\n\nInteraction of the E. coli Cell Wall with Periplasmic Macromolecules: Multiscale Simulat ions (Prof. Syma Khalid)\n\nFrom Sequence to Mechanism: Probing the Altern ating-Access Cycle of Cystinosin with Enhanced-Sampling Molecular Dynamics and QM/MM simulations (Dr Jonathan Colburn)\n\nAntimicrobial Peptide Beha viour in the E. coli Cell Envelope: The Complexity Matters (Cyril Schroede r)\nSpeakers:\nProfessor Syma Khalid (University of Oxford)\, Dr Jonathan Colburn (University of Oxford)\, Cyril Schroeder (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/656b20b7-bc79-4432-a16f-fd2dfbf38a63/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Annual BPS meeting talks - Professor Syma Khalid (Univers ity of Oxford)\, Dr Jonathan Colburn (University of Oxford)\, Cyril Schroe der (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Improved alchemical free energy calculations: Enhanced configurati onal sampling\, flexibility\, parallelizability\, and more - Dr Wei-Tse Hs u (University of Oxford) DTSTART;VALUE=DATE-TIME:20250213T140000Z DTEND;VALUE=DATE-TIME:20250213T150000Z UID:https://talks.ox.ac.uk/talks/id/47c8fac8-c5d8-4d4b-b2ae-36b59174be19/ DESCRIPTION:\nSpeakers:\nDr Wei-Tse Hsu (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/47c8fac8-c5d8-4d4b-b2ae-36b59174be19/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Improved alchemical free energy calculations: Enhanced co nfigurational sampling\, flexibility\, parallelizability\, and more - Dr W ei-Tse Hsu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Identification of state-dependent\, drug-permeable fenestrations i n glycine receptors - Bjarne Feddersen DTSTART;VALUE=DATE-TIME:20250130T140000Z DTEND;VALUE=DATE-TIME:20250130T150000Z UID:https://talks.ox.ac.uk/talks/id/32babe52-e2bc-4a15-8107-ee916645d2b1/ DESCRIPTION:\nSpeakers:\nBjarne Feddersen LOCATION:Dorothy Crowfoot Hodgkin Building (40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/32babe52-e2bc-4a15-8107-ee916645d2b1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Identification of state-dependent\, drug-permeable fenest rations in glycine receptors - Bjarne Feddersen TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:In silico development of fluorescent sensors to dissect cell signa ling pathways - Dr Florencia Klein Rocha (University of Oxford) DTSTART;VALUE=DATE-TIME:20250123T150000Z DTEND;VALUE=DATE-TIME:20250123T160000Z UID:https://talks.ox.ac.uk/talks/id/98574c29-2a82-4ca2-b73a-333309dd9393/ DESCRIPTION:\nSpeakers:\nDr Florencia Klein Rocha (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 2\, 20-138)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/98574c29-2a82-4ca2-b73a-333309dd9393/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:In silico development of fluorescent sensors to dissect c ell signaling pathways - Dr Florencia Klein Rocha (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Real time conditional resolution transformation with ConTra - Dr I ain Smith (University of Oxford) DTSTART;VALUE=DATE-TIME:20250116T140000Z DTEND;VALUE=DATE-TIME:20250116T150000Z UID:https://talks.ox.ac.uk/talks/id/05d7a614-d594-44f5-9a01-f082774d57da/ DESCRIPTION:\nSpeakers:\nDr Iain Smith (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/05d7a614-d594-44f5-9a01-f082774d57da/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Real time conditional resolution transformation with ConT ra - Dr Iain Smith (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20250109T140000Z DTEND;VALUE=DATE-TIME:20250109T150000Z UID:https://talks.ox.ac.uk/talks/id/28a3c71b-9c4a-4ec6-bf3a-a86c9bb4608c/ DESCRIPTION:\nSpeakers:\nDr Charlotte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/28a3c71b-9c4a-4ec6-bf3a-a86c9bb4608c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Cooling fast and slow: preserved and disrupted populations from cr yo-em vitrification - Robert Clark (University of Oxford) DTSTART;VALUE=DATE-TIME:20241205T140000Z DTEND;VALUE=DATE-TIME:20241205T150000Z UID:https://talks.ox.ac.uk/talks/id/ae342439-bfdc-4110-b723-c266628baee0/ DESCRIPTION:\nSpeakers:\nRobert Clark (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ae342439-bfdc-4110-b723-c266628baee0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Cooling fast and slow: preserved and disrupted population s from cryo-em vitrification - Robert Clark (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Absolute alchemical binding free energy calculations on membrane t argets - Nithishwer Mouroug Anand (University of Oxford) DTSTART;VALUE=DATE-TIME:20241128T140000Z DTEND;VALUE=DATE-TIME:20241128T150000Z UID:https://talks.ox.ac.uk/talks/id/b14c9b13-17c2-425a-90be-99074f2106dc/ DESCRIPTION:\nSpeakers:\nNithishwer Mouroug Anand (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b14c9b13-17c2-425a-90be-99074f2106dc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Absolute alchemical binding free energy calculations on m embrane targets - Nithishwer Mouroug Anand (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Elucidating Antimicrobial Peptide Interactions with Gram-Negative Bacterial Membranes Using Computational Electrophysiology - Cyril Schroede r (University of Oxford) DTSTART;VALUE=DATE-TIME:20241121T150000Z DTEND;VALUE=DATE-TIME:20241121T160000Z UID:https://talks.ox.ac.uk/talks/id/60dc3222-5152-4253-9ce6-429e69eccceb/ DESCRIPTION:\nSpeakers:\nCyril Schroeder (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/60dc3222-5152-4253-9ce6-429e69eccceb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Elucidating Antimicrobial Peptide Interactions with Gram- Negative Bacterial Membranes Using Computational Electrophysiology - Cyril Schroeder (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Membrane self-assembly simulations to assess protein insertion: a case of Phi29 connector pore - Aleksandr Kovalenko (University of Oxford) DTSTART;VALUE=DATE-TIME:20241114T140000Z DTEND;VALUE=DATE-TIME:20241114T150000Z UID:https://talks.ox.ac.uk/talks/id/dae59a00-793b-4c1a-8929-a35ed586ad78/ DESCRIPTION:\nSpeakers:\nAleksandr Kovalenko (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/dae59a00-793b-4c1a-8929-a35ed586ad78/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Membrane self-assembly simulations to assess protein inse rtion: a case of Phi29 connector pore - Aleksandr Kovalenko (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Reducing Intracranial Pressure by Targeting Ncbe - Lasse Desdorf DTSTART;VALUE=DATE-TIME:20241107T140000Z DTEND;VALUE=DATE-TIME:20241107T150000Z UID:https://talks.ox.ac.uk/talks/id/3ffaba65-def3-47f6-8016-951c3fbfc9ed/ DESCRIPTION:\nSpeakers:\nLasse Desdorf LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3ffaba65-def3-47f6-8016-951c3fbfc9ed/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Reducing Intracranial Pressure by Targeting Ncbe - Lasse Desdorf TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Probing KDEL Receptor Activation with Molecular Dynamics - Dr Jon athan Colburn (University of Oxford) DTSTART;VALUE=DATE-TIME:20241031T140000Z DTEND;VALUE=DATE-TIME:20241031T150000Z UID:https://talks.ox.ac.uk/talks/id/3d397c6a-d667-464b-b1b9-cd1b91deb77a/ DESCRIPTION:\nSpeakers:\nDr Jonathan Colburn (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3d397c6a-d667-464b-b1b9-cd1b91deb77a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Probing KDEL Receptor Activation with Molecular Dynamics - Dr Jonathan Colburn (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Transport in plants: The devil is in the molecular details - Dr Lo rena Zuzic (Department of Chemistry\, Aarhus University) DTSTART;VALUE=DATE-TIME:20241024T140000 DTEND;VALUE=DATE-TIME:20241024T150000 UID:https://talks.ox.ac.uk/talks/id/0ec9dd29-ea71-4e54-904d-97b4f407ed4c/ DESCRIPTION:\nSpeakers:\nDr Lorena Zuzic (Department of Chemistry\, Aarhus University) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/0ec9dd29-ea71-4e54-904d-97b4f407ed4c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Transport in plants: The devil is in the molecular detail s - Dr Lorena Zuzic (Department of Chemistry\, Aarhus University) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational Microbiology and other things - Prof Syma Khalid (D ept of Biochemistry\, University of Oxford) DTSTART;VALUE=DATE-TIME:20241017T150000 DTEND;VALUE=DATE-TIME:20241017T160000 UID:https://talks.ox.ac.uk/talks/id/ed192e37-60c6-4f99-ba75-0d5462060a72/ DESCRIPTION:\nSpeakers:\nProf Syma Khalid (Dept of Biochemistry\, Universi ty of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1\, 20-026)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ed192e37-60c6-4f99-ba75-0d5462060a72/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational Microbiology and other things - Prof Syma Khalid (Dept of Biochemistry\, University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Simulations and AI to understand membrane protein dynamics and dru g actions - Professor Phil Biggin (Dept. of Biochemistry\, University of O xford) DTSTART;VALUE=DATE-TIME:20241010T140000 DTEND;VALUE=DATE-TIME:20241010T150000 UID:https://talks.ox.ac.uk/talks/id/b7609735-fd11-49a2-9c65-00bf7ad575aa/ DESCRIPTION:\nSpeakers:\nProfessor Phil Biggin (Dept. of Biochemistry\, Un iversity of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b7609735-fd11-49a2-9c65-00bf7ad575aa/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Simulations and AI to understand membrane protein dynamic s and drug actions - Professor Phil Biggin (Dept. of Biochemistry\, Univer sity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Deep learning for structure based drug discovery - Prof David Ryan Koes (University of Pittsburgh) DTSTART;VALUE=DATE-TIME:20240628T160000 DTEND;VALUE=DATE-TIME:20240628T170000 UID:https://talks.ox.ac.uk/talks/id/48508d41-c961-445d-9474-de51d5d5e554/ DESCRIPTION:\nWe will describe the training and development of convolution al neural networks for protein-ligand scoring and how these deep learning models are integrated into the GNINA molecular docking open source softwar e. Successful prospective evaluations of GNINA will be discussed\, includi ng recent top performance in the Critical Assessment of Computational Hit- Finding Experiments (CACHE). Additionally\, we will describe our open sou rce pharmacophore screening resource\, Pharmit\, which enables the screeni ng of millions of compounds in seconds and discuss several generative appr oaches for hit discovery using deep generative models.\nSpeakers:\nProf Da vid Ryan Koes (University of Pittsburgh) LOCATION:Dorothy Crowfoot Hodgkin Building (Seminar Room 1 )\, off South P arks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/48508d41-c961-445d-9474-de51d5d5e554/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Deep learning for structure based drug discovery - Prof D avid Ryan Koes (University of Pittsburgh) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Are popular force fields good enough for soluble crowded systems? - Nikolai Juraschko (University of Oxford) DTSTART;VALUE=DATE-TIME:20240509T140000 DTEND;VALUE=DATE-TIME:20240509T150000 UID:https://talks.ox.ac.uk/talks/id/720e3943-af68-4299-ab8e-a91edb6bb9b8/ DESCRIPTION:\nSpeakers:\nNikolai Juraschko (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/720e3943-af68-4299-ab8e-a91edb6bb9b8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Are popular force fields good enough for soluble crowded systems? - Nikolai Juraschko (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20240627T143000 DTEND;VALUE=DATE-TIME:20240627T153000 UID:https://talks.ox.ac.uk/talks/id/8612f6d4-3004-408c-b9c7-1cd43986b270/ DESCRIPTION:\nStatus: This talk is in preparation - details may change\n\n Speakers:\nDaniel Crusius (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 2 Ground Floor Main Semi nar Room (20-138))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8612f6d4-3004-408c-b9c7-1cd43986b270/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20240620T143000 DTEND;VALUE=DATE-TIME:20240620T153000 UID:https://talks.ox.ac.uk/talks/id/c0dbae1c-d38d-4131-9cdb-496edf70e42a/ DESCRIPTION:\nStatus: This talk is in preparation - details may change\n LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c0dbae1c-d38d-4131-9cdb-496edf70e42a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20240613T140000 DTEND;VALUE=DATE-TIME:20240613T150000 UID:https://talks.ox.ac.uk/talks/id/986dd44e-c89b-4734-b3f5-67c8bc18c423/ DESCRIPTION:\nStatus: This talk is in preparation - details may change\n LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/986dd44e-c89b-4734-b3f5-67c8bc18c423/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20240606T140000 DTEND;VALUE=DATE-TIME:20240606T150000 UID:https://talks.ox.ac.uk/talks/id/a47b8a3c-9c77-40fe-89cd-f4390e39914c/ DESCRIPTION:\nStatus: This talk is in preparation - details may change\n\n Speakers:\nIain Smith (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a47b8a3c-9c77-40fe-89cd-f4390e39914c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20240530T140000 DTEND;VALUE=DATE-TIME:20240530T150000 UID:https://talks.ox.ac.uk/talks/id/d9a1af0c-8d41-49ce-be41-5828d9c4a694/ DESCRIPTION:\nStatus: This talk has been cancelled\n\nSpeakers:\nKahlan Ne wman (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d9a1af0c-8d41-49ce-be41-5828d9c4a694/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Exploring the performance of ABFE calculations in membrane bound d rug targets - Nithishwer Mouroug Anand (University of Oxford) DTSTART;VALUE=DATE-TIME:20240523T140000 DTEND;VALUE=DATE-TIME:20240523T150000 UID:https://talks.ox.ac.uk/talks/id/a657d439-ca5f-4f8d-85c6-d4dd1dc7180f/ DESCRIPTION:\nSpeakers:\nNithishwer Mouroug Anand (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a657d439-ca5f-4f8d-85c6-d4dd1dc7180f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Exploring the performance of ABFE calculations in membran e bound drug targets - Nithishwer Mouroug Anand (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Insertion of Polymyxin B1 into the E. coli outer membrane revealed by large-scale molecular dynamics simulations - Dheeraj Prakaash (Univers ity of Oxford) DTSTART;VALUE=DATE-TIME:20240516T140000 DTEND;VALUE=DATE-TIME:20240516T150000 UID:https://talks.ox.ac.uk/talks/id/e8906f71-8dfa-4d6e-bc8c-7a703188792f/ DESCRIPTION:\nSpeakers:\nDheeraj Prakaash (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e8906f71-8dfa-4d6e-bc8c-7a703188792f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Insertion of Polymyxin B1 into the E. coli outer membrane revealed by large-scale molecular dynamics simulations - Dheeraj Prakaash (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II Talks - Evan Burke (University of Oxford) DTSTART;VALUE=DATE-TIME:20240502T140000 DTEND;VALUE=DATE-TIME:20240502T150000 UID:https://talks.ox.ac.uk/talks/id/7d2fe245-877d-47f3-ac8c-5aef9224647b/ DESCRIPTION:\nSpeakers:\nEvan Burke (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7d2fe245-877d-47f3-ac8c-5aef9224647b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II Talks - Evan Burke (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II Talks - Ho Chu (University of Oxford)\, Carl von Hallerste in (University of Oxford) DTSTART;VALUE=DATE-TIME:20240425T140000 DTEND;VALUE=DATE-TIME:20240425T150000 UID:https://talks.ox.ac.uk/talks/id/309e7cb1-be4c-409c-ba90-ff41b35065ac/ DESCRIPTION:\nSpeakers:\nHo Chu (University of Oxford)\, Carl von Hallerst ein (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/309e7cb1-be4c-409c-ba90-ff41b35065ac/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II Talks - Ho Chu (University of Oxford)\, Carl von Hallerstein (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:How can we use molecular dynamics to understand lipid transport in bacteria? - Robert Clark (University of Oxford) DTSTART;VALUE=DATE-TIME:20240321T140000Z DTEND;VALUE=DATE-TIME:20240321T150000Z UID:https://talks.ox.ac.uk/talks/id/e8438738-62f0-4003-9281-999932458ac9/ DESCRIPTION:\nSpeakers:\nRobert Clark (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e8438738-62f0-4003-9281-999932458ac9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:How can we use molecular dynamics to understand lipid tra nsport in bacteria? - Robert Clark (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Redesign of Phi29 connector protein for membrane insertion through self-assembly simulations - Aleksandr Kovalenko (University of Oxford) DTSTART;VALUE=DATE-TIME:20240314T140000Z DTEND;VALUE=DATE-TIME:20240314T150000Z UID:https://talks.ox.ac.uk/talks/id/9b71ff08-9e48-489d-bef4-3bd84c6bc325/ DESCRIPTION:\nSpeakers:\nAleksandr Kovalenko (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 2 Second Floor Northeast Meeting Room (40-091))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9b71ff08-9e48-489d-bef4-3bd84c6bc325/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Redesign of Phi29 connector protein for membrane insertio n through self-assembly simulations - Aleksandr Kovalenko (University of O xford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Absolute binding free energy calculations for membrane targets in the TRPC3/6 subfamily of proteins - Nithishwer Mouroug Anand (University of Oxford) DTSTART;VALUE=DATE-TIME:20240307T110000Z DTEND;VALUE=DATE-TIME:20240307T120000Z UID:https://talks.ox.ac.uk/talks/id/74918b7a-91bd-4f43-bb0f-958b73ecbfc8/ DESCRIPTION:\nSpeakers:\nNithishwer Mouroug Anand (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/74918b7a-91bd-4f43-bb0f-958b73ecbfc8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Absolute binding free energy calculations for membrane ta rgets in the TRPC3/6 subfamily of proteins - Nithishwer Mouroug Anand (Un iversity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Utilising Molecular Dynamics to Study the Interaction of Multivale nt Dendrimer with E.coli Outer Membrane - Mingyu Qin (University of Oxford ) DTSTART;VALUE=DATE-TIME:20240229T140000Z DTEND;VALUE=DATE-TIME:20240229T150000Z UID:https://talks.ox.ac.uk/talks/id/bf52e839-a961-498f-a116-52087db1fdd2/ DESCRIPTION:\nSpeakers:\nMingyu Qin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/bf52e839-a961-498f-a116-52087db1fdd2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Utilising Molecular Dynamics to Study the Interaction of Multivalent Dendrimer with E.coli Outer Membrane - Mingyu Qin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:What’s lipids got to do with it? What’s lipids\, but a second- hand emulsion? - Dr. Tim Carpenter (Lawrence Livermore National Laboratory ) DTSTART;VALUE=DATE-TIME:20240201T150000Z DTEND;VALUE=DATE-TIME:20240201T160000Z UID:https://talks.ox.ac.uk/talks/id/c16347bf-1d10-4804-9d9e-6f808ee8b6d9/ DESCRIPTION:Integral membrane proteins that are embedded in the cellular p lasma membrane make up the vast majority of all approved drug targets. How ever\, the contributions of the membrane lipids to the function and behavi or of these membrane-embedded proteins have for years been neglected. Ofte n the membrane itself is seen as just a ‘scaffold’ to hold the protein in place. Using a range of integrated computational and experimental meth ods (several developed specifically for this project)\, we explore the int eractions between membrane proteins and their surrounding lipid environmen ts to reveal just how intricate\, detailed\, and balanced the relationship is.\nSpeakers:\nDr. Tim Carpenter (Lawrence Livermore National Laboratory ) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c16347bf-1d10-4804-9d9e-6f808ee8b6d9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:What’s lipids got to do with it? What’s lipids\, but a second-hand emulsion? - Dr. Tim Carpenter (Lawrence Livermore National L aboratory) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular dynamics of RNA translocation through a nanopore - Zephy r Ford (University of Oxford) DTSTART;VALUE=DATE-TIME:20240222T140000Z DTEND;VALUE=DATE-TIME:20240222T150000Z UID:https://talks.ox.ac.uk/talks/id/92f003d3-7bfe-4937-a402-c49b4e8adc84/ DESCRIPTION:\nSpeakers:\nZephyr Ford (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/92f003d3-7bfe-4937-a402-c49b4e8adc84/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular dynamics of RNA translocation through a nanopor e - Zephyr Ford (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:OpenFE: community-driven open source tooling for alchemistry - Dr Irfan Alibay DTSTART;VALUE=DATE-TIME:20240125T150000Z DTEND;VALUE=DATE-TIME:20240125T160000Z UID:https://talks.ox.ac.uk/talks/id/ac81eb85-1901-4ab5-95ab-05ea628de1b9/ DESCRIPTION:Meeting ID: 346 331 487 460\nPasscode: hTHEC4\n\nSpeakers:\nDr Irfan Alibay LOCATION:Dorothy Crowfoot Hodgkin Building (Online Only)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ac81eb85-1901-4ab5-95ab-05ea628de1b9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:OpenFE: community-driven open source tooling for alchemis try - Dr Irfan Alibay TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Predicting Antimicrobial Resistance to Rifampicin in Mycobacterium Tuberculosis using Machine Learning - Dr Charlotte Lynch (University of O xford) DTSTART;VALUE=DATE-TIME:20240118T150000Z DTEND;VALUE=DATE-TIME:20240118T160000Z UID:https://talks.ox.ac.uk/talks/id/e698fb9d-258b-4a11-ae9c-b43c55555eac/ DESCRIPTION:\nSpeakers:\nDr Charlotte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e698fb9d-258b-4a11-ae9c-b43c55555eac/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Predicting Antimicrobial Resistance to Rifampicin in Myco bacterium Tuberculosis using Machine Learning - Dr Charlotte Lynch (Univer sity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Preferential Lipid Interactions of the KDEL Receptor Revealed by M olecular Dynamics - Dr Jonathan Colburn (University of Oxford) DTSTART;VALUE=DATE-TIME:20240111T150000Z DTEND;VALUE=DATE-TIME:20240111T160000Z UID:https://talks.ox.ac.uk/talks/id/08f96d12-110d-4a45-a964-be2899dff4ee/ DESCRIPTION:\nSpeakers:\nDr Jonathan Colburn (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 Ground Floor Main Semi nar Room (20-026))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/08f96d12-110d-4a45-a964-be2899dff4ee/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Preferential Lipid Interactions of the KDEL Receptor Reve aled by Molecular Dynamics - Dr Jonathan Colburn (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Paving the way for modelling coarse-grained carbohydrates - Dr Ast rid Bradner (University of Oxford) DTSTART;VALUE=DATE-TIME:20231130T140000Z DTEND;VALUE=DATE-TIME:20231130T150000Z UID:https://talks.ox.ac.uk/talks/id/c4485cbb-a402-4130-b060-b87a83b31c81/ DESCRIPTION:\nSpeakers:\nDr Astrid Bradner (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c4485cbb-a402-4130-b060-b87a83b31c81/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Paving the way for modelling coarse-grained carbohydrates - Dr Astrid Bradner (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Quantifying Ion Channel Pore Asymmetry: Exploring its influence on conductance and barrier to permeation - David Seiferth DTSTART;VALUE=DATE-TIME:20231123T140000Z DTEND;VALUE=DATE-TIME:20231123T150000Z UID:https://talks.ox.ac.uk/talks/id/3dabcd3e-17af-4751-bba9-a55c64fc2fa2/ DESCRIPTION:\nSpeakers:\nDavid Seiferth LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3dabcd3e-17af-4751-bba9-a55c64fc2fa2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Quantifying Ion Channel Pore Asymmetry: Exploring its inf luence on conductance and barrier to permeation - David Seiferth TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Plasticity of the selectivity filter is essential for ion permeati on in lysosomal TPC2 channels - Dr Afroditi-Maria Zaki ( University of Oxf ord) DTSTART;VALUE=DATE-TIME:20231116T140000Z DTEND;VALUE=DATE-TIME:20231116T150000Z UID:https://talks.ox.ac.uk/talks/id/9ba6aecc-43fc-404d-a07e-bccd142a26a2/ DESCRIPTION:\nSpeakers:\nDr Afroditi-Maria Zaki ( University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9ba6aecc-43fc-404d-a07e-bccd142a26a2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Plasticity of the selectivity filter is essential for ion permeation in lysosomal TPC2 channels - Dr Afroditi-Maria Zaki ( Universi ty of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Effects of system complexity on interactions between antimicrobial peptides and the cell envelope of Gram-negative bacteria - Cyril Schroede r (University of Oxford) DTSTART;VALUE=DATE-TIME:20231109T140000Z DTEND;VALUE=DATE-TIME:20231109T150000Z UID:https://talks.ox.ac.uk/talks/id/6c3d8d20-84f4-4521-a0c6-7c8cda1a918e/ DESCRIPTION:\nSpeakers:\nCyril Schroeder (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6c3d8d20-84f4-4521-a0c6-7c8cda1a918e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Effects of system complexity on interactions between anti microbial peptides and the cell envelope of Gram-negative bacteria - Cyril Schroeder (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:What is computational microbiology? - Professor Syma Khalid (Unive rsity of Oxford) DTSTART;VALUE=DATE-TIME:20231102T140000Z DTEND;VALUE=DATE-TIME:20231102T150000Z UID:https://talks.ox.ac.uk/talks/id/ac9956a8-9b67-4c9b-84ed-e95e3b459891/ DESCRIPTION:\nSpeakers:\nProfessor Syma Khalid (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ac9956a8-9b67-4c9b-84ed-e95e3b459891/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:What is computational microbiology? - Professor Syma Khal id (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular mechanisms of drug transport through peptide transporter s - Simon Lichtinger (University of Oxford) DTSTART;VALUE=DATE-TIME:20231026T140000 DTEND;VALUE=DATE-TIME:20231026T150000 UID:https://talks.ox.ac.uk/talks/id/5d302a9d-a1f2-4edb-83d3-dd0af7956872/ DESCRIPTION:\nSpeakers:\nSimon Lichtinger (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5d302a9d-a1f2-4edb-83d3-dd0af7956872/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular mechanisms of drug transport through peptide tr ansporters - Simon Lichtinger (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:What is Computational Microbiology? - Professor Syma Khalid (Unive rsity of Oxford) DTSTART;VALUE=DATE-TIME:20231019T140000 DTEND;VALUE=DATE-TIME:20231019T150000 UID:https://talks.ox.ac.uk/talks/id/3f9634cb-e7cf-4c9e-b25e-4d7864c565ca/ DESCRIPTION:\nStatus: This talk has been cancelled\n\nSpeakers:\nProfessor Syma Khalid (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3f9634cb-e7cf-4c9e-b25e-4d7864c565ca/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:What is Computational Microbiology? - Professor Syma Khal id (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20231012T140000 DTEND;VALUE=DATE-TIME:20231012T150000 UID:https://talks.ox.ac.uk/talks/id/daaaf01b-c00c-43c7-9972-bfb7d3486258/ DESCRIPTION:\nStatus: This talk is in preparation - details may change\n\n Speakers:\nProf Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemistry Teaching Centre ( 10-022))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/daaaf01b-c00c-43c7-9972-bfb7d3486258/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:TCR-pMHC complex formation triggers CD3 dynamics - Floris van Eerd en (iFReC\, Osaka University) DTSTART;VALUE=DATE-TIME:20230907T140000 DTEND;VALUE=DATE-TIME:20230907T150000 UID:https://talks.ox.ac.uk/talks/id/a06791ee-184d-476b-b764-c35363fcd865/ DESCRIPTION:The T cell receptor (TCR) plays an important role in the immun e system by recognizing peptide antigens presented by the major histocompa tibility complex (MHC). Despite decades of research\, the TCR remains enig matic\, as it is not clear how binding of an immunogenic peptide-MHC compl ex (pMHC) is signaled over the plasma membrane. The TCR lacks a cytoplasmi c domain\, but forms a complex with the CD3 proteins\, which have long cyt oplasmic tails that contain the ITAM motifs\, which are phosphorylated upo n TCR-pMHC binding. It has been conceptually difficult to understand how e xtracellular TCR-pMHC binding results in the phosphorylation of the ITAMs inside the cell\; the TCR lacks a proper cytoplasmic domain\, while the CD 3 proteins are too short to interact with the pMHC. The fact that the TCR and CD3 associate non-covalently further complicates the problem. Based up on extensive molecular dynamics simulations\, we present an allosteric mec hanism for TCR triggering upon pMHC binding for which we obtained experime ntal support.\n\nvan Eerden Floris J.\, Sherif Aalaa Alrahman\, Llamas-Cov arrubias Mara Anais\, Millius Arthur\, Lu Xiuyuan\, Ishizuka Shigenari\, Y amasaki Sho\, Standley Daron M. (2023) TCR-pMHC complex formation triggers CD3 dynamics eLife 12:RP88065\n\nhttps://doi.org/10.7554/eLife.88065.1\nS peakers:\nFloris van Eerden (iFReC\, Osaka University) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 2 Second Floor Northeast Meeting Room (40-091))\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a06791ee-184d-476b-b764-c35363fcd865/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:TCR-pMHC complex formation triggers CD3 dynamics - Floris van Eerden (iFReC\, Osaka University) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Analog Computing for Molecular Dynamics Simulations - William Roch ira (University of Oxford) DTSTART;VALUE=DATE-TIME:20230629T140000 DTEND;VALUE=DATE-TIME:20230629T150000 UID:https://talks.ox.ac.uk/talks/id/2c6c46e5-fe4b-4390-bed1-00996c3f3cd0/ DESCRIPTION:\nSpeakers:\nWilliam Rochira (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (BTC - Phase 1 Lower Ground Flo or Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2c6c46e5-fe4b-4390-bed1-00996c3f3cd0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Analog Computing for Molecular Dynamics Simulations - Wil liam Rochira (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Life on the edge: an integrative modelling approach to solving str uctures in situ - Zephyr Ford (University of Oxford) DTSTART;VALUE=DATE-TIME:20230720T140000 DTEND;VALUE=DATE-TIME:20230720T150000 UID:https://talks.ox.ac.uk/talks/id/6d9bb64e-a7ec-4e1f-9fc9-1d291146a3a8/ DESCRIPTION:\nSpeakers:\nZephyr Ford (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6d9bb64e-a7ec-4e1f-9fc9-1d291146a3a8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Life on the edge: an integrative modelling approach to so lving structures in situ - Zephyr Ford (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Developing and sharing biomolecular simulation methods for modelli ng protein-ligand interactions - Julien Michel (University of Edinburgh) DTSTART;VALUE=DATE-TIME:20230330T140000 DTEND;VALUE=DATE-TIME:20230330T150000 UID:https://talks.ox.ac.uk/talks/id/d52803c5-74ad-4a4a-95ef-6dea81cba8bf/ DESCRIPTION:\nSpeakers:\nJulien Michel (University of Edinburgh) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d52803c5-74ad-4a4a-95ef-6dea81cba8bf/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Developing and sharing biomolecular simulation methods fo r modelling protein-ligand interactions - Julien Michel (University of Edi nburgh) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Machine learning vs protein conformational spaces - Matteo Degiaco mi (Durham University) DTSTART;VALUE=DATE-TIME:20221124T150000Z DTEND;VALUE=DATE-TIME:20221124T160000Z UID:https://talks.ox.ac.uk/talks/id/83c0e850-835d-43b4-829a-eae4bd54cc9e/ DESCRIPTION:Determining the different conformational states of a protein a nd the transition paths between them is key to fully understanding the rel ationship between biomolecular structure and function. I will discuss how a neural network can learn a continuous conformational space representatio n from example structures produced by molecular dynamics simulations. I wi ll then show how such representation\, obtained via our software molearn ( 1)\, can be leveraged to predict putative protein transition states (2)\, or to generate conformations useful in the context of flexible protein-pro tein docking (3).\n\n1. https://github.com/Degiacomi-Lab/molearn\n2. V.K. Ramaswamy et al.\, Learning Protein Conformational Space with Convolutions and Latent Interpolations. Physical Review X (2021).\n3. M.T. Degiacomi\, Coupling Molecular Dynamics and Deep Learning to Mine Protein Conformatio nal Space. Structure (2019)\nSpeakers:\nMatteo Degiacomi (Durham Universit y) LOCATION:Dorothy Crowfoot Hodgkin Building (20-138 Phase 2 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/83c0e850-835d-43b4-829a-eae4bd54cc9e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Machine learning vs protein conformational spaces - Matte o Degiacomi (Durham University) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 c omplex: Insights from molecular dynamics - Jon Colburn (University of Oxfo rd) DTSTART;VALUE=DATE-TIME:20230112T150000Z DTEND;VALUE=DATE-TIME:20230112T160000Z UID:https://talks.ox.ac.uk/talks/id/3fee0398-266a-410c-8219-685ebd3808dc/ DESCRIPTION:\nSpeakers:\nJon Colburn (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Online)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3fee0398-266a-410c-8219-685ebd3808dc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Structural basis of peptidoglycan synthesis by E. coli Ro dA-PBP2 complex: Insights from molecular dynamics - Jon Colburn (Universit y of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Bacterial chemotaxis and methane metabolism: structure-function an alysis of the underlying supramolecular assemblies - Keith Cassidy (Univer sity of Oxford) DTSTART;VALUE=DATE-TIME:20221117T140000Z DTEND;VALUE=DATE-TIME:20221117T150000Z UID:https://talks.ox.ac.uk/talks/id/a3c4b224-c50b-4e9d-b5fc-107f468f7b5b/ DESCRIPTION:\nSpeakers:\nKeith Cassidy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a3c4b224-c50b-4e9d-b5fc-107f468f7b5b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Bacterial chemotaxis and methane metabolism: structure-fu nction analysis of the underlying supramolecular assemblies - Keith Cassid y (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Making Martini 3 sweeter: extension to simulate oligosaccharides i n a generalised fashion - Astrid Brandner (University of Oxford) DTSTART;VALUE=DATE-TIME:20221103T130000Z DTEND;VALUE=DATE-TIME:20221103T140000Z UID:https://talks.ox.ac.uk/talks/id/9cce072b-cacf-49dc-b45b-6bf82ed122be/ DESCRIPTION:\nSpeakers:\nAstrid Brandner (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building ( 20-138 Phase 2 Ground Floor M ain Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9cce072b-cacf-49dc-b45b-6bf82ed122be/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Making Martini 3 sweeter: extension to simulate oligosacc harides in a generalised fashion - Astrid Brandner (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Insights into the multiple roles played by lipopolysaccharides (LP S) in the outer membrane of E. coli - Dheeraj Prakaash (University of Oxfo rd) DTSTART;VALUE=DATE-TIME:20230727T140000 DTEND;VALUE=DATE-TIME:20230727T150000 UID:https://talks.ox.ac.uk/talks/id/65c3d188-e9bc-45cf-929d-96e6856b1988/ DESCRIPTION:\nSpeakers:\nDheeraj Prakaash (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/65c3d188-e9bc-45cf-929d-96e6856b1988/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Insights into the multiple roles played by lipopolysaccha rides (LPS) in the outer membrane of E. coli - Dheeraj Prakaash (Universit y of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20230713T140000 DTEND;VALUE=DATE-TIME:20230713T150000 UID:https://talks.ox.ac.uk/talks/id/81c499a3-a0ae-42dd-8b91-a1297cc36a79/ DESCRIPTION:\nSpeakers:\nNikolai Juraschko (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/81c499a3-a0ae-42dd-8b91-a1297cc36a79/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Influence of Electronic Polarisation on Anion Behaviour within Ion Channels and Nanopores - Linda Phan (University of Oxford) DTSTART;VALUE=DATE-TIME:20230706T140000 DTEND;VALUE=DATE-TIME:20230706T150000 UID:https://talks.ox.ac.uk/talks/id/d8e89583-4c7a-4d21-ae4b-343aa73f3e56/ DESCRIPTION:\nSpeakers:\nLinda Phan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d8e89583-4c7a-4d21-ae4b-343aa73f3e56/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Influence of Electronic Polarisation on Anion Behaviour w ithin Ion Channels and Nanopores - Linda Phan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Machine Learning Based Tools for Force-Field Development and Enhan ced Sampling - Dr. Linfeng Zhang (DP Technology) DTSTART;VALUE=DATE-TIME:20230623T140000 DTEND;VALUE=DATE-TIME:20230623T150000 UID:https://talks.ox.ac.uk/talks/id/372c1489-b0de-4fd6-b1ca-d53347e06239/ DESCRIPTION:\nSpeakers:\nDr. Linfeng Zhang (DP Technology) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/372c1489-b0de-4fd6-b1ca-d53347e06239/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Machine Learning Based Tools for Force-Field Development and Enhanced Sampling - Dr. Linfeng Zhang (DP Technology) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Multiscale investigations into lipid transporters - Robert Clark ( University of Oxford) DTSTART;VALUE=DATE-TIME:20230615T140000 DTEND;VALUE=DATE-TIME:20230615T150000 UID:https://talks.ox.ac.uk/talks/id/f0206bfb-a1f5-4f94-a648-446ec5332110/ DESCRIPTION:\nSpeakers:\nRobert Clark (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f0206bfb-a1f5-4f94-a648-446ec5332110/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Multiscale investigations into lipid transporters - Rober t Clark (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Absolute binding free energy calculations for membrane targets in the TRPC3/6 subfamily of proteins - Nithishwer Mouroug Anand (University o f Oxford) DTSTART;VALUE=DATE-TIME:20230608T140000 DTEND;VALUE=DATE-TIME:20230608T150000 UID:https://talks.ox.ac.uk/talks/id/cc4302ca-fc21-4cbe-be16-ba5896ffac96/ DESCRIPTION:\nSpeakers:\nNithishwer Mouroug Anand (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/cc4302ca-fc21-4cbe-be16-ba5896ffac96/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Absolute binding free energy calculations for membrane ta rgets in the TRPC3/6 subfamily of proteins - Nithishwer Mouroug Anand (Uni versity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Multiscale modelling of transmembrane transport processes with kin etic cycle models - Oliver Beckstein (Arizona State University) DTSTART;VALUE=DATE-TIME:20230601T140000 DTEND;VALUE=DATE-TIME:20230601T150000 UID:https://talks.ox.ac.uk/talks/id/88cf2b1e-4a66-4645-8a53-5ce98b378538/ DESCRIPTION:Microsoft Teams meeting\nMeeting ID: 329 678 834 717 \nPasscod e: aExbPR \nSpeakers:\nOliver Beckstein (Arizona State University) LOCATION:Dorothy Crowfoot Hodgkin Building (Online only - see abstract for details)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/88cf2b1e-4a66-4645-8a53-5ce98b378538/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Multiscale modelling of transmembrane transport processes with kinetic cycle models - Oliver Beckstein (Arizona State University) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Integrative Approaches in Fragment-Based Drug Discovery - Harold G rosjean (University of Oxford) DTSTART;VALUE=DATE-TIME:20230518T140000 DTEND;VALUE=DATE-TIME:20230518T150000 UID:https://talks.ox.ac.uk/talks/id/ae3172d9-4f6a-4b0e-9697-fe0ec09da942/ DESCRIPTION:\nSpeakers:\nHarold Grosjean (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ae3172d9-4f6a-4b0e-9697-fe0ec09da942/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Integrative Approaches in Fragment-Based Drug Discovery - Harold Grosjean (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Structure-based discovery of opioid and nonopioid analgesics - Pro f. Dr. Peter Gmeiner (University of Erlangen-Nuremberg) DTSTART;VALUE=DATE-TIME:20230511T140000 DTEND;VALUE=DATE-TIME:20230511T150000 UID:https://talks.ox.ac.uk/talks/id/752c4024-71cc-4c07-9713-97f46c157d69/ DESCRIPTION:\nSpeakers:\nProf. Dr. Peter Gmeiner (University of Erlangen-N uremberg) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/752c4024-71cc-4c07-9713-97f46c157d69/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Structure-based discovery of opioid and nonopioid analges ics - Prof. Dr. Peter Gmeiner (University of Erlangen-Nuremberg) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Mixed - see abstract - Bailey Cameron (University of Oxford)\, Fer gus Waterhouse (University of Oxford) DTSTART;VALUE=DATE-TIME:20230504T140000 DTEND;VALUE=DATE-TIME:20230504T150000 UID:https://talks.ox.ac.uk/talks/id/6e2af6bd-0bfb-4c5f-b6d5-23c7422464b1/ DESCRIPTION:Bailey Cameron: Estimation of Ion Conductance of Biomimetic Na nopores\nFergus Waterhouse: TBA\nSpeakers:\nBailey Cameron (University of Oxford)\, Fergus Waterhouse (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Online Only)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6e2af6bd-0bfb-4c5f-b6d5-23c7422464b1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Mixed - see abstract - Bailey Cameron (University of Oxfo rd)\, Fergus Waterhouse (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Mixed - see abstract - Jonathon Puleston (University of Oxford)\, Lilia Evgeniou (University of Oxford) DTSTART;VALUE=DATE-TIME:20230427T140000 DTEND;VALUE=DATE-TIME:20230427T150000 UID:https://talks.ox.ac.uk/talks/id/b210a977-51a2-4748-a244-0d0fcb6c1d4e/ DESCRIPTION:Jonathon Puleston: Molecular Dynamics and synthesis of BRD4 ta rgeting PROTACs\nLilia Evgeniou: Electroosmosis in nanopores for polypepti de translocation\nSpeakers:\nJonathon Puleston (University of Oxford)\, Li lia Evgeniou (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b210a977-51a2-4748-a244-0d0fcb6c1d4e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Mixed - see abstract - Jonathon Puleston (University of O xford)\, Lilia Evgeniou (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Khalid group: Microbiology with computers - Professor Syma Khalid (University of Oxford) DTSTART;VALUE=DATE-TIME:20221013T141500 DTEND;VALUE=DATE-TIME:20221013T151500 UID:https://talks.ox.ac.uk/talks/id/7f32abd7-ab79-4101-9541-45201019ff4a/ DESCRIPTION:\nSpeakers:\nProfessor Syma Khalid (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7f32abd7-ab79-4101-9541-45201019ff4a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Khalid group: Microbiology with computers - Professor Sym a Khalid (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Applied Computer Science in Computational Virology - Tyler Reddy ( Los Alamos National Laboratory) DTSTART;VALUE=DATE-TIME:20230323T140000Z DTEND;VALUE=DATE-TIME:20230323T150000Z UID:https://talks.ox.ac.uk/talks/id/50ea4128-e70b-4706-99c5-8b35f3d02d01/ DESCRIPTION:Microsoft Teams meeting\nMeeting ID: 333 180 978 150\nPasscode : pz4HYg\nSpeakers:\nTyler Reddy (Los Alamos National Laboratory) LOCATION:Dorothy Crowfoot Hodgkin Building (Online)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/50ea4128-e70b-4706-99c5-8b35f3d02d01/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Applied Computer Science in Computational Virology - Tyle r Reddy (Los Alamos National Laboratory) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The Fast and the Accurate? Cheminformatics and Molecular Dynamics for Cyclic Peptide Structure Prediction - Daniel Crusius (University of Ox ford) DTSTART;VALUE=DATE-TIME:20230316T140000Z DTEND;VALUE=DATE-TIME:20230316T150000Z UID:https://talks.ox.ac.uk/talks/id/9051b149-a210-4f9a-969e-069f220274e9/ DESCRIPTION:\nSpeakers:\nDaniel Crusius (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9051b149-a210-4f9a-969e-069f220274e9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The Fast and the Accurate? Cheminformatics and Molecular Dynamics for Cyclic Peptide Structure Prediction - Daniel Crusius (Univers ity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The mechanism of mammalian peptide transporters - Simon Lichtinger (University of Oxford) DTSTART;VALUE=DATE-TIME:20230309T140000Z DTEND;VALUE=DATE-TIME:20230309T150000Z UID:https://talks.ox.ac.uk/talks/id/b45fbdf1-e2af-4089-af66-9dddf3aa4643/ DESCRIPTION:\nSpeakers:\nSimon Lichtinger (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b45fbdf1-e2af-4089-af66-9dddf3aa4643/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The mechanism of mammalian peptide transporters - Simon L ichtinger (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Open Force Field: next generation force fields with open software\ , open data\, and open science - Lily Wang (Open Force Field Initiative) DTSTART;VALUE=DATE-TIME:20230302T140000Z DTEND;VALUE=DATE-TIME:20230302T150000Z UID:https://talks.ox.ac.uk/talks/id/105b9ceb-cc8f-409a-ac5a-171f67358007/ DESCRIPTION:Microsoft Teams meeting\nMeeting ID: 330 645 388 419 \nPasscod e: srm3EV\nSpeakers:\nLily Wang (Open Force Field Initiative) LOCATION:Dorothy Crowfoot Hodgkin Building (Online)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/105b9ceb-cc8f-409a-ac5a-171f67358007/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Open Force Field: next generation force fields with open software\, open data\, and open science - Lily Wang (Open Force Field Init iative) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:BPS Review Session - BPS Presenters (University of Oxford) DTSTART;VALUE=DATE-TIME:20230209T150000Z DTEND;VALUE=DATE-TIME:20230209T160000Z UID:https://talks.ox.ac.uk/talks/id/f21eed45-3935-4895-ae52-34dbd777290a/ DESCRIPTION:\nSpeakers:\nBPS Presenters (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-138 Phase 2 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f21eed45-3935-4895-ae52-34dbd777290a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:BPS Review Session - BPS Presenters (University of Oxford ) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20230202T140000Z DTEND;VALUE=DATE-TIME:20230202T150000Z UID:https://talks.ox.ac.uk/talks/id/5691f594-e57b-4050-9b90-34e7bddd7142/ DESCRIPTION:\nStatus: This talk has been cancelled\n\nSpeakers:\nEmad Tajk horshid (University of Illinois at Urbana-Champaign) LOCATION:Dorothy Crowfoot Hodgkin Building (Online)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5691f594-e57b-4050-9b90-34e7bddd7142/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:FEP calculations on GPCRs - Eduard Neu (Friedrich-Alexander-Univer sität Erlangen-Nürnberg) DTSTART;VALUE=DATE-TIME:20230126T140000Z DTEND;VALUE=DATE-TIME:20230126T150000Z UID:https://talks.ox.ac.uk/talks/id/fa2b3867-17eb-4fa0-be23-77b612e278a4/ DESCRIPTION:\nSpeakers:\nEduard Neu (Friedrich-Alexander-Universität Erla ngen-Nürnberg) LOCATION:Dorothy Crowfoot Hodgkin Building (Online)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fa2b3867-17eb-4fa0-be23-77b612e278a4/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:FEP calculations on GPCRs - Eduard Neu (Friedrich-Alexand er-Universität Erlangen-Nürnberg) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Aberrant TRPC3 signalling in Spinocerebellar Ataxias - Jodie Colli ngridge (University of Oxford) DTSTART;VALUE=DATE-TIME:20230119T140000Z DTEND;VALUE=DATE-TIME:20230119T150000Z UID:https://talks.ox.ac.uk/talks/id/4ff20706-65f3-4404-8b55-c5b7911c3a06/ DESCRIPTION:\nSpeakers:\nJodie Collingridge (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Online)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4ff20706-65f3-4404-8b55-c5b7911c3a06/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Aberrant TRPC3 signalling in Spinocerebellar Ataxias - Jo die Collingridge (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Manipulate molecules in Virtual Reality with Narupa - Jonathan Bar noud (University of Bristol) DTSTART;VALUE=DATE-TIME:20221201T140000Z DTEND;VALUE=DATE-TIME:20221201T150000Z UID:https://talks.ox.ac.uk/talks/id/b7b887c0-230b-4238-aa66-6b1211284121/ DESCRIPTION:Microsoft Teams meeting\nMeeting ID: 367 821 590 046 \nPasscod e: 463Lxc\n\nhttps://teams.microsoft.com/l/meetup-join/19%3ameeting_ZGJiMT U1NjYtMzc3NC00YzUyLWIwZmMtNWNhYjA3MGUwZmU3%40thread.v2/0?context=%7b%22Tid %22%3a%22cc95de1b-97f5-4f93-b4ba-fe68b852cf91%22%2c%22Oid%22%3a%221548cf41 -ecb5-4eef-ba0b-876d02ba5004%22%7d\nSpeakers:\nJonathan Barnoud (Universit y of Bristol) LOCATION:Dorothy Crowfoot Hodgkin Building (Online Only)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b7b887c0-230b-4238-aa66-6b1211284121/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Manipulate molecules in Virtual Reality with Narupa - Jon athan Barnoud (University of Bristol) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Elucidating the interaction patterns between antimicrobial peptide s and the cell envelopes of Gram-negative bacteria using molecular dynamic s simulations - Cyril Schroeder (University of Oxford) DTSTART;VALUE=DATE-TIME:20221110T140000Z DTEND;VALUE=DATE-TIME:20221110T150000Z UID:https://talks.ox.ac.uk/talks/id/f45c995e-8c97-4068-b5d2-2428e2931450/ DESCRIPTION:\nSpeakers:\nCyril Schroeder (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f45c995e-8c97-4068-b5d2-2428e2931450/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Elucidating the interaction patterns between antimicrobia l peptides and the cell envelopes of Gram-negative bacteria using molecula r dynamics simulations - Cyril Schroeder (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Effects of induced polarisation on nanoscale behaviour of anions i n anion carriers - David Seiferth DTSTART;VALUE=DATE-TIME:20221027T140000 DTEND;VALUE=DATE-TIME:20221027T150000 UID:https://talks.ox.ac.uk/talks/id/1df542f7-4ea7-40bd-8573-bb7b58174832/ DESCRIPTION:\nSpeakers:\nDavid Seiferth LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1df542f7-4ea7-40bd-8573-bb7b58174832/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Effects of induced polarisation on nanoscale behaviour of anions in anion carriers - David Seiferth TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Simulations to understand membrane protein dynamics and drug actio ns - Prof Phil Biggin (University of Oxford) DTSTART;VALUE=DATE-TIME:20221006T140000 DTEND;VALUE=DATE-TIME:20221006T150000 UID:https://talks.ox.ac.uk/talks/id/b39c899d-0c59-4b51-a25e-9057c096dd2a/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (20-026 Phase 1 Ground Floor Ma in Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b39c899d-0c59-4b51-a25e-9057c096dd2a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Simulations to understand membrane protein dynamics and d rug actions - Prof Phil Biggin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Predicting Antimicrobial Resistance in Mycobacterium Tuberculosis using Machine Learning with Protein Structural and Chemical Features - Dr Charlotte Lynch (University of Oxford) DTSTART;VALUE=DATE-TIME:20220714T140000 DTEND;VALUE=DATE-TIME:20220714T150000 UID:https://talks.ox.ac.uk/talks/id/c85946e6-1d11-4e4c-a5cd-a4bb0f1a8ea3/ DESCRIPTION:\nSpeakers:\nDr Charlotte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (New Biochemistry Phase 1 Main Seminar Room )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c85946e6-1d11-4e4c-a5cd-a4bb0f1a8ea3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Predicting Antimicrobial Resistance in Mycobacterium Tube rculosis using Machine Learning with Protein Structural and Chemical Featu res - Dr Charlotte Lynch (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Antimicrobial Peptides and the Multiple Peptide Resistance Factor: Molecular Dynamics Simulations to understand Antimicrobial resistance - P atrick Simcock (University of Oxford) DTSTART;VALUE=DATE-TIME:20220616T140000 DTEND;VALUE=DATE-TIME:20220616T150000 UID:https://talks.ox.ac.uk/talks/id/35b9d365-a34c-474e-bc1e-7223c06fd8e5/ DESCRIPTION:\nSpeakers:\nPatrick Simcock (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 seminar room)\, off So uth Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/35b9d365-a34c-474e-bc1e-7223c06fd8e5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Antimicrobial Peptides and the Multiple Peptide Resistanc e Factor: Molecular Dynamics Simulations to understand Antimicrobial resis tance - Patrick Simcock (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Atomistic mechanisms of human TRPA1 activation by electrophile irr itants - David Seiferth DTSTART;VALUE=DATE-TIME:20220707T140000 DTEND;VALUE=DATE-TIME:20220707T150000 UID:https://talks.ox.ac.uk/talks/id/37ecba44-b120-4dce-bf5f-a5f9ba32fea5/ DESCRIPTION:\nSpeakers:\nDavid Seiferth LOCATION:Dorothy Crowfoot Hodgkin Building (Biochemsitry phase 2 second fl oor meeting room 40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/37ecba44-b120-4dce-bf5f-a5f9ba32fea5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Atomistic mechanisms of human TRPA1 activation by electro phile irritants - David Seiferth TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Investigation and Application of a Versatile Model Membrane System by Combining Molecular Dynamic Simulations with Neutron Reflectometry Ex periments - Laura John (University of Oxford) DTSTART;VALUE=DATE-TIME:20220623T140000 DTEND;VALUE=DATE-TIME:20220623T150000 UID:https://talks.ox.ac.uk/talks/id/06a1cfad-e613-40bd-a4b1-06a43c36d50e/ DESCRIPTION:\nSpeakers:\nLaura John (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase 1 seminar room - Zoom li nk TBD)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/06a1cfad-e613-40bd-a4b1-06a43c36d50e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Investigation and Application of a Versatile Model Membra ne System by Combining Molecular Dynamic Simulations with Neutron Reflect ometry Experiments - Laura John (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Activation and inhibition of kinases that are central to leukaemia s: lessons from computational chemistry (and some experiments too) - Prof Ran Friedman (Linnaeus University\, Kalmar\, Sweden) DTSTART;VALUE=DATE-TIME:20220523T140000 DTEND;VALUE=DATE-TIME:20220523T150000 UID:https://talks.ox.ac.uk/talks/id/711db5f4-2a52-470b-b962-d319dfe35a0f/ DESCRIPTION:ABL1 and FLT3 are two kinases that become overactive in leukae mias. Constitutively active ABL1 is the hallmark of chronic myeloid leukae mia (CML)\, whereas mutations in the gene encoding FLT3 are seen in 35% of the patients that suffer from acute myeloid leukaemia (AML). Inhibitors o f these kinases are used to treat these leukaemias\, but the development o f resistance is common. The main cause of resistance in both cases are mut ations in the gene encoding the target protein. While one would expect tha t resistance mutations interfere with protein-drug interactions directly\, this is oftentimes not the case. The mutations can have different working mechanisms\, such as making the enzyme adopt a conformation that does not bind the drug or which make it more efficient. We used a computational ap proach to study the effect of resistance mutations with computer simulatio ns\, ranging from classical molecular dynamics (MD) to more advanced metho ds that involve enhanced sampling. Our efforts led to a better understandi ng of these mutations and their effects on the molecular level. Some of th ese studies were followed up by enzymatic assays in the lab. In parallel t o our studies of resistance mutations\, we have also followed on the mecha nism of enzyme activation. Using enhanced sampling methods we could deciph er how these two enzymes become activated\, something that could not be un derstood solely from experiments. Overall\, our studies contributed to a b etter understanding of (pathological) enzyme activation and drug resistanc e from a molecular point of view\, and provide useful set-up for the devel opment of better drugs in CML and AML\nSpeakers:\nProf Ran Friedman (Linna eus University\, Kalmar\, Sweden) LOCATION:Dorothy Crowfoot Hodgkin Building (New Biochemistry Phase 1 Main Seminar Room - Zoom: https://us02web.zoom.us/j/3817847572)\, off South Pa rks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/711db5f4-2a52-470b-b962-d319dfe35a0f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Activation and inhibition of kinases that are central to leukaemias: lessons from computational chemistry (and some experiments too ) - Prof Ran Friedman (Linnaeus University\, Kalmar\, Sweden) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:A Simulation Study of the Salmonella O-antigen Acyltransferase Pro tein\, OafB​ - Kahlan Newman (University of Southampton) DTSTART;VALUE=DATE-TIME:20220630T140000 DTEND;VALUE=DATE-TIME:20220630T150000 UID:https://talks.ox.ac.uk/talks/id/95801036-53ac-42b2-96a8-ba73ba67e2d2/ DESCRIPTION:\nSpeakers:\nKahlan Newman (University of Southampton) LOCATION:ONLINE TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/95801036-53ac-42b2-96a8-ba73ba67e2d2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:A Simulation Study of the Salmonella O-antigen Acyltransf erase Protein\, OafB​ - Kahlan Newman (University of Southampton) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Using computational tools to improve our understanding of voltage- sensing in sodium channe - Bjarne Feddersen DTSTART;VALUE=DATE-TIME:20220519T140000 DTEND;VALUE=DATE-TIME:20220519T150000 UID:https://talks.ox.ac.uk/talks/id/7c93b7e5-1007-46d1-b184-292a4dc01e8c/ DESCRIPTION:\nSpeakers:\nBjarne Feddersen LOCATION:Dorothy Crowfoot Hodgkin Building (New Biochemistry Phase 1 Main Seminar Room )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7c93b7e5-1007-46d1-b184-292a4dc01e8c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Using computational tools to improve our understanding of voltage-sensing in sodium channe - Bjarne Feddersen TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:‘Computational approaches to allosteric ligand discovery for P2Y 1 receptor’/ 'Molecular Dynamics simulations for Determining H2/O2 selec tion Mechanisms in and Oxygen Tolerant Hydrogenase' - Jack Badley\, Jessie Jiang DTSTART;VALUE=DATE-TIME:20220512T140000 DTEND;VALUE=DATE-TIME:20220512T150000 UID:https://talks.ox.ac.uk/talks/id/c2cdcaee-baed-40fd-abf2-dcbe834594a5/ DESCRIPTION:\nSpeakers:\nJack Badley\, Jessie Jiang LOCATION:Dorothy Crowfoot Hodgkin Building (New Biochemistry Phase 1 Main Seminar Room )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c2cdcaee-baed-40fd-abf2-dcbe834594a5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:‘Computational approaches to allosteric ligand discover y for P2Y1 receptor’/ 'Molecular Dynamics simulations for Determining H2 /O2 selection Mechanisms in and Oxygen Tolerant Hydrogenase' - Jack Badley \, Jessie Jiang TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:'Computational Studies on LSM12 as an NAADP-binding Protein and it s Role in Activating the TPC2 Channel' / 'Mutational analysis of cholester ol binding in Large Neutral Amino Acid Transporter 1 (LAT1/SLC7A5)' - Tian yi Shi\, Daniel Standing DTSTART;VALUE=DATE-TIME:20220505T140000 DTEND;VALUE=DATE-TIME:20220505T150000 UID:https://talks.ox.ac.uk/talks/id/4a7674d0-d62c-4fbc-b77d-65a260eff7b0/ DESCRIPTION:\nSpeakers:\nTianyi Shi\, Daniel Standing LOCATION:Dorothy Crowfoot Hodgkin Building (New Biochemistry Phase 2 North east meeting room 40-091)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4a7674d0-d62c-4fbc-b77d-65a260eff7b0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:'Computational Studies on LSM12 as an NAADP-binding Prote in and its Role in Activating the TPC2 Channel' / 'Mutational analysis of cholesterol binding in Large Neutral Amino Acid Transporter 1 (LAT1/SLC7A5 )' - Tianyi Shi\, Daniel Standing TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Alchemical absolute binding free energy calculations at the protei n-bilayer interface - Charlie Cook (University of Oxford) DTSTART;VALUE=DATE-TIME:20220331T140000 DTEND;VALUE=DATE-TIME:20220331T150000 UID:https://talks.ox.ac.uk/talks/id/5bd89e8d-8a4b-4a96-99c3-dd4979282fc3/ DESCRIPTION:\nSpeakers:\nCharlie Cook (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5bd89e8d-8a4b-4a96-99c3-dd4979282fc3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Alchemical absolute binding free energy calculations at t he protein-bilayer interface - Charlie Cook (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:"Patched1\, cholesterol and ions - what is going on?" - Bertie Ans ell (University of Oxford) DTSTART;VALUE=DATE-TIME:20220317T140000Z DTEND;VALUE=DATE-TIME:20220317T150000Z UID:https://talks.ox.ac.uk/talks/id/97b3f671-d6a3-469e-a6b3-e7c8c7297799/ DESCRIPTION:\nSpeakers:\nBertie Ansell (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/97b3f671-d6a3-469e-a6b3-e7c8c7297799/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:"Patched1\, cholesterol and ions - what is going on?" - B ertie Ansell (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20220310T140000Z DTEND;VALUE=DATE-TIME:20220310T150000Z UID:https://talks.ox.ac.uk/talks/id/e380d49c-5e3c-48af-813e-11c3e2ef677d/ DESCRIPTION:\nSpeakers:\nZonghua Bo (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e380d49c-5e3c-48af-813e-11c3e2ef677d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Onto recent advances in high-throughput fragment-based drug discov ery at the XChem - Harold Grosjean (University of Oxford) DTSTART;VALUE=DATE-TIME:20220303T140000Z DTEND;VALUE=DATE-TIME:20220303T150000Z UID:https://talks.ox.ac.uk/talks/id/2a51e102-f7d1-4b1a-88bf-672241071a79/ DESCRIPTION:\nSpeakers:\nHarold Grosjean (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2a51e102-f7d1-4b1a-88bf-672241071a79/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Onto recent advances in high-throughput fragment-based dr ug discovery at the XChem - Harold Grosjean (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Studying TRIM PHD-bromodomain interactions with histone H3 peptide s using MD simulations DTSTART;VALUE=DATE-TIME:20220217T140000Z DTEND;VALUE=DATE-TIME:20220217T150000Z UID:https://talks.ox.ac.uk/talks/id/051629d1-296c-4750-a60b-89d01196a707/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/051629d1-296c-4750-a60b-89d01196a707/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Studying TRIM PHD-bromodomain interactions with histone H 3 peptides using MD simulations TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Simulations of metallorganic cages: development of cationic dummy model of palladium - Tomasz Piskorz (University of Oxford) DTSTART;VALUE=DATE-TIME:20220210T140000Z DTEND;VALUE=DATE-TIME:20220210T150000Z UID:https://talks.ox.ac.uk/talks/id/7ae53e9a-90bf-460d-9930-7d2d36d4b500/ DESCRIPTION:\nSpeakers:\nTomasz Piskorz (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7ae53e9a-90bf-460d-9930-7d2d36d4b500/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Simulations of metallorganic cages: development of cation ic dummy model of palladium - Tomasz Piskorz (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Parametrization and applications of coarse-grained molecular dynam ics simulations - Sophie Mader DTSTART;VALUE=DATE-TIME:20220127T140000Z DTEND;VALUE=DATE-TIME:20220127T150000Z UID:https://talks.ox.ac.uk/talks/id/7f81252d-4d7f-4fd8-aaf8-7a8fd91c6965/ DESCRIPTION:\nSpeakers:\nSophie Mader LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7f81252d-4d7f-4fd8-aaf8-7a8fd91c6965/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Parametrization and applications of coarse-grained molecu lar dynamics simulations - Sophie Mader TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Recent innovations in methods for predicting protein-ligand bindin g - David Mobley (University of California Irvine) DTSTART;VALUE=DATE-TIME:20220203T140000Z DTEND;VALUE=DATE-TIME:20220203T150000Z UID:https://talks.ox.ac.uk/talks/id/616a9ae5-550c-4b11-88c1-3f8bcbba4a8d/ DESCRIPTION:\nSpeakers:\nDavid Mobley (University of California Irvine) LOCATION:Dorothy Crowfoot Hodgkin Building (https://us02web.zoom.us/j/8953 2314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3 QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/616a9ae5-550c-4b11-88c1-3f8bcbba4a8d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Recent innovations in methods for predicting protein-liga nd binding - David Mobley (University of California Irvine) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Correction schemes for absolute binding free energies involving li pid bilayers - Will Wu DTSTART;VALUE=DATE-TIME:20220113T140000Z DTEND;VALUE=DATE-TIME:20220113T150000Z UID:https://talks.ox.ac.uk/talks/id/6ea6b1df-0763-4bab-bb92-557134f93e05/ DESCRIPTION:\nSpeakers:\nWill Wu LOCATION:Dorothy Crowfoot Hodgkin Building\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6ea6b1df-0763-4bab-bb92-557134f93e05/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Correction schemes for absolute binding free energies inv olving lipid bilayers - Will Wu TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Theory of biomolecular discrimination - Dr. John McBride (Institut e for Basic Science) DTSTART;VALUE=DATE-TIME:20211209T140000Z DTEND;VALUE=DATE-TIME:20211209T150000Z UID:https://talks.ox.ac.uk/talks/id/7029c4ca-c6b6-430e-bb92-ad351544acb3/ DESCRIPTION:Proteins need to selectively interact with specific targets am ong a multitude of similar molecules in the cell. Despite a physical under standing of pairwise binding interactions\, we lack a general theory of ho w proteins evolve high specificity. Here\, we present a genetic\, mechano- chemical model of evolving protein-ligand interactions which offers a mech anistic understanding of molecular discrimination: There are many routes t o achieving discrimination – varying degrees of flexibility and shape/ch emistry complementarity – but the key ingredient is precision. Harder di scrimination tasks require more collective and precise interplay of struct ure\, forces and dynamics. Proteins can achieve this through correlated mu tations extending far from a binding site\, which fine tune the localized interaction with the ligand. Thus\, the solution of more complicated tasks requires larger proteins\, and proteins become more evolvable and robust when they are larger than the bare minimum required for discrimination. Ou r model makes testable\, specific predictions about the role of flexibilit y in discrimination\, how to independently tune affinity and specificity. Thus\, the proposed theory of molecular discrimination sheds light on a qu estion that is often taken for granted – “why are proteins so big?” One possible answer is\, “because molecular discrimination is often a ha rd task.”\nSpeakers:\nDr. John McBride (Institute for Basic Science) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7029c4ca-c6b6-430e-bb92-ad351544acb3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Theory of biomolecular discrimination - Dr. John McBride (Institute for Basic Science) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Antimicrobial Peptides: Interactions with Modified Bacterial Membr anes - Patrick Simcock (University of Oxford) DTSTART;VALUE=DATE-TIME:20211202T140000Z DTEND;VALUE=DATE-TIME:20211202T150000Z UID:https://talks.ox.ac.uk/talks/id/c429dcf0-72b5-4150-8c78-fb83298d587a/ DESCRIPTION:\nStatus: This talk has been cancelled\n\nSpeakers:\nPatrick S imcock (University of Oxford) LOCATION:Biochemistry Phase 1 Main Seminar Room and https://us02web.zoom.u s/j/89532314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09 TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c429dcf0-72b5-4150-8c78-fb83298d587a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Antimicrobial Peptides: Interactions with Modified Bacter ial Membranes - Patrick Simcock (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:MacroConf – Dataset & Workflows to assess cyclic peptide solutio n structures - Daniel Crusius (University of Oxford) DTSTART;VALUE=DATE-TIME:20211104T140000Z DTEND;VALUE=DATE-TIME:20211104T150000Z UID:https://talks.ox.ac.uk/talks/id/c928991d-91ad-44e4-902a-42f643c39efe/ DESCRIPTION:\nSpeakers:\nDaniel Crusius (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (New Biochemistry Phase 2 Room '40-091' and online at: https://us02web.zoom.us/j/89532314583?pwd=c0IrT21o a1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c928991d-91ad-44e4-902a-42f643c39efe/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:MacroConf – Dataset & Workflows to assess cyclic peptid e solution structures - Daniel Crusius (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational investigation of the SARS-CoV-2 main protease - Ho C han (University of Oxford) DTSTART;VALUE=DATE-TIME:20211125T140000Z DTEND;VALUE=DATE-TIME:20211125T150000Z UID:https://talks.ox.ac.uk/talks/id/56c32fca-b810-43b5-be24-3951b620de47/ DESCRIPTION:\nSpeakers:\nHo Chan (University of Oxford) LOCATION:New Biochemistry Phase 1 Main Seminar Room and https://us02web.zo om.us/j/89532314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09 TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/56c32fca-b810-43b5-be24-3951b620de47/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational investigation of the SARS-CoV-2 main protea se - Ho Chan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Insights into bacterial cell envelopes from molecular simulations - Professor Syma Khalid (University of Oxford) DTSTART;VALUE=DATE-TIME:20211118T140000Z DTEND;VALUE=DATE-TIME:20211118T150000Z UID:https://talks.ox.ac.uk/talks/id/8d9949ad-a0d9-4076-ac97-90bf4e77faa2/ DESCRIPTION:\nSpeakers:\nProfessor Syma Khalid (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Phase I seminar room\, https:/ /us02web.zoom.us/j/89532314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8d9949ad-a0d9-4076-ac97-90bf4e77faa2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Insights into bacterial cell envelopes from molecular sim ulations - Professor Syma Khalid (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:An overview of simulations approaches to understand membrane prote ins dynamics and drug action - Prof Phil Biggin (University of Oxford) DTSTART;VALUE=DATE-TIME:20211111T140000Z DTEND;VALUE=DATE-TIME:20211111T150000Z UID:https://talks.ox.ac.uk/talks/id/44e91ecb-041b-421b-8f4a-49fe348ee1a1/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:New Biochemistry Phase 1 Main Seminar Room and online at: https:/ /us02web.zoom.us/j/89532314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09 TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/44e91ecb-041b-421b-8f4a-49fe348ee1a1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:An overview of simulations approaches to understand membr ane proteins dynamics and drug action - Prof Phil Biggin (University of Ox ford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Drug transport through peptide transporters - Simon Lichtinger (Un iversity of Oxford) DTSTART;VALUE=DATE-TIME:20211028T140000 DTEND;VALUE=DATE-TIME:20211028T150000 UID:https://talks.ox.ac.uk/talks/id/f0cb88af-c54b-4aeb-9f5a-016af030c945/ DESCRIPTION:\nSpeakers:\nSimon Lichtinger (University of Oxford) LOCATION:https://us02web.zoom.us/j/89532314583?pwd=c0IrT21oa1lJNDJMdEFqcUw 0S0pMZz09 TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f0cb88af-c54b-4aeb-9f5a-016af030c945/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Drug transport through peptide transporters - Simon Licht inger (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Structural\, functional and computational studies of SLC7 transpor ters - Dimitrios Kolokouris (University of Oxford) DTSTART;VALUE=DATE-TIME:20211021T140000 DTEND;VALUE=DATE-TIME:20211021T150000 UID:https://talks.ox.ac.uk/talks/id/680ef307-4fe7-4350-ac08-ba4c8809e81d/ DESCRIPTION:\nSpeakers:\nDimitrios Kolokouris (University of Oxford) LOCATION:HybrId meeting\; New Biochemistry room 40-091 AND https://us02web .zoom.us/j/89532314583?pwd=c0IrT21oa1lJNDJMdEFqcUw0S0pMZz09 TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/680ef307-4fe7-4350-ac08-ba4c8809e81d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Structural\, functional and computational studies of SLC7 transporters - Dimitrios Kolokouris (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular dynamics of the mitochondrial Lon protease - Lauren Alex andrescu (University of Oxford) DTSTART;VALUE=DATE-TIME:20211007T140000 DTEND;VALUE=DATE-TIME:20211007T150000 UID:https://talks.ox.ac.uk/talks/id/e04760f4-350e-42b1-a552-4922257eef2e/ DESCRIPTION:\nSpeakers:\nLauren Alexandrescu (University of Oxford) LOCATION:Virtual TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e04760f4-350e-42b1-a552-4922257eef2e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular dynamics of the mitochondrial Lon protease - La uren Alexandrescu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:MDAnalysis 2.0 and beyond - towards fast and interoperable simulat ion analyses - Dr Irfan Alibay (University of Oxford) DTSTART;VALUE=DATE-TIME:20210923T140000 DTEND;VALUE=DATE-TIME:20210923T150000 UID:https://talks.ox.ac.uk/talks/id/edc7da40-df1a-4175-8f51-1d1bf8b8805c/ DESCRIPTION:\nSpeakers:\nDr Irfan Alibay (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Held over zoom\, )\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/edc7da40-df1a-4175-8f51-1d1bf8b8805c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:MDAnalysis 2.0 and beyond - towards fast and interoperabl e simulation analyses - Dr Irfan Alibay (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Modelling and simulation of SARS-CoV-2 spike glycoprotein - Firdau s Samsudin (A*STAR) DTSTART;VALUE=DATE-TIME:20210624T140000 DTEND;VALUE=DATE-TIME:20210624T150000 UID:https://talks.ox.ac.uk/talks/id/2f21b133-9e63-4e38-96d2-b0ef7263116c/ DESCRIPTION:\nSpeakers:\nFirdaus Samsudin (A*STAR) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2f21b133-9e63-4e38-96d2-b0ef7263116c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Modelling and simulation of SARS-CoV-2 spike glycoprotein - Firdaus Samsudin (A*STAR) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Versatile Model Membrane System for Investigating Membrane Protein s - Laura John (University of Oxford) DTSTART;VALUE=DATE-TIME:20210617T140000 DTEND;VALUE=DATE-TIME:20210617T150000 UID:https://talks.ox.ac.uk/talks/id/6d84d339-2946-4e78-a689-a4e9febd074e/ DESCRIPTION:\nSpeakers:\nLaura John (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6d84d339-2946-4e78-a689-a4e9febd074e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Versatile Model Membrane System for Investigating Membran e Proteins - Laura John (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Analysis of cardiolipin interactions with E. coli inner membrane p roteins - Dr Robin Corey (University of Oxford) DTSTART;VALUE=DATE-TIME:20210520T140000 DTEND;VALUE=DATE-TIME:20210520T150000 UID:https://talks.ox.ac.uk/talks/id/9478b956-d7ca-469f-9b65-210ade7f7afd/ DESCRIPTION:\nSpeakers:\nDr Robin Corey (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9478b956-d7ca-469f-9b65-210ade7f7afd/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Analysis of cardiolipin interactions with E. coli inner m embrane proteins - Dr Robin Corey (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Tanadet Pipatpolkai (University of Oxford) DTSTART;VALUE=DATE-TIME:20210603T140000 DTEND;VALUE=DATE-TIME:20210603T150000 UID:https://talks.ox.ac.uk/talks/id/f3b5cccc-8f38-4088-899f-755046d0f5e1/ DESCRIPTION:\nSpeakers:\nTanadet Pipatpolkai (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Held over zoom\, https://us02w eb.zoom.us/j/87941734423?pwd=bXNiMHU2MnBVVVlSRVBTVlBvMkVydz09 contact Robi n Corey for more details)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f3b5cccc-8f38-4088-899f-755046d0f5e1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Tanadet Pipatpolkai (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Understanding the function of mechanosensitive channels using mult iscale molecular dynamics simulations. - Dr Antreas Kalli (Leeds Institute of Cancer and Pathology\, St James's University Hospital\, University of Leeds) DTSTART;VALUE=DATE-TIME:20210527T140000 DTEND;VALUE=DATE-TIME:20210527T150000 UID:https://talks.ox.ac.uk/talks/id/255f7ea4-fe85-4ce7-9392-31308a8804f7/ DESCRIPTION:\nSpeakers:\nDr Antreas Kalli (Leeds Institute of Cancer and P athology\, St James's University Hospital\, University of Leeds) LOCATION:Dorothy Crowfoot Hodgkin Building (Held over zoom\, https://us02w eb.zoom.us/j/87941734423?pwd=bXNiMHU2MnBVVVlSRVBTVlBvMkVydz09 contact Robi n Corey for more details)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/255f7ea4-fe85-4ce7-9392-31308a8804f7/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Understanding the function of mechanosensitive channels u sing multiscale molecular dynamics simulations. - Dr Antreas Kalli (Leeds Institute of Cancer and Pathology\, St James's University Hospital\, Unive rsity of Leeds) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Relative Affinities of Protein-Cholesterol Interactions from Equil ibrium Molecular Dynamics Simulations - Bertie Ansell (University of Oxfor d) DTSTART;VALUE=DATE-TIME:20210513T140000 DTEND;VALUE=DATE-TIME:20210513T150000 UID:https://talks.ox.ac.uk/talks/id/3338dd1f-1194-452b-a902-07eebf4f2dce/ DESCRIPTION:\nSpeakers:\nBertie Ansell (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Held over zoom\, https://us02w eb.zoom.us/j/87941734423?pwd=bXNiMHU2MnBVVVlSRVBTVlBvMkVydz09 contact Robi n Corey for more details)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3338dd1f-1194-452b-a902-07eebf4f2dce/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Relative Affinities of Protein-Cholesterol Interactions f rom Equilibrium Molecular Dynamics Simulations - Bertie Ansell (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II talks DTSTART;VALUE=DATE-TIME:20210506T140000 DTEND;VALUE=DATE-TIME:20210506T150000 UID:https://talks.ox.ac.uk/talks/id/ac1670b9-7dc3-4ab9-9f1c-6a9bc50c0fbd/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ac1670b9-7dc3-4ab9-9f1c-6a9bc50c0fbd/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II talks DTSTART;VALUE=DATE-TIME:20210422T140000 DTEND;VALUE=DATE-TIME:20210422T150000 UID:https://talks.ox.ac.uk/talks/id/b6d5e791-c666-4508-81e7-27a3d97dd1fe/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b6d5e791-c666-4508-81e7-27a3d97dd1fe/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Dr Lucy Forrest (National Institutes of Health) DTSTART;VALUE=DATE-TIME:20210415T140000 DTEND;VALUE=DATE-TIME:20210415T150000 UID:https://talks.ox.ac.uk/talks/id/dd8e60ca-a8df-429f-8ad8-50885335d671/ DESCRIPTION:\nSpeakers:\nDr Lucy Forrest (National Institutes of Health) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/dd8e60ca-a8df-429f-8ad8-50885335d671/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Dr Lucy Forrest (National Institutes of He alth) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Nanopore Design for Site-selective Modifications of Biomolecules - Zonghua (Ally) Bo (University of Oxford) DTSTART;VALUE=DATE-TIME:20210318T140000Z DTEND;VALUE=DATE-TIME:20210318T150000Z UID:https://talks.ox.ac.uk/talks/id/e09a24a5-7198-4c0f-add2-001970be2828/ DESCRIPTION:\nSpeakers:\nZonghua (Ally) Bo (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e09a24a5-7198-4c0f-add2-001970be2828/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Nanopore Design for Site-selective Modifications of Biomo lecules - Zonghua (Ally) Bo (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Modulation of A2a Receptor Oligomerisation by Conformational State and PIP2 Interactions Revealed by MD Simulations and Markov Models - Dr W anling Song (University of Oxford) DTSTART;VALUE=DATE-TIME:20210311T140000Z DTEND;VALUE=DATE-TIME:20210311T150000Z UID:https://talks.ox.ac.uk/talks/id/76cede91-4c61-4dda-b09a-865ec25985f9/ DESCRIPTION:\nSpeakers:\nDr Wanling Song (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/76cede91-4c61-4dda-b09a-865ec25985f9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Modulation of A2a Receptor Oligomerisation by Conformatio nal State and PIP2 Interactions Revealed by MD Simulations and Markov Mode ls - Dr Wanling Song (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Conformational transition and substrate binding of the bile acid t ransporter ASBTnm - Fiona Naughton (Arizona State University) DTSTART;VALUE=DATE-TIME:20210304T140000Z DTEND;VALUE=DATE-TIME:20210304T150000Z UID:https://talks.ox.ac.uk/talks/id/c13f7351-fefc-49ea-a9c6-e4d6374c86bd/ DESCRIPTION:\nSpeakers:\nFiona Naughton (Arizona State University) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c13f7351-fefc-49ea-a9c6-e4d6374c86bd/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Conformational transition and substrate binding of the bi le acid transporter ASBTnm - Fiona Naughton (Arizona State University) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Exploring binding properties of the "lipid-anchors": FYVE and C2 - how to reveal binding strength and orientation by multi-scale MD. - Andre as Larsen (University of Oxford) DTSTART;VALUE=DATE-TIME:20210211T140000Z DTEND;VALUE=DATE-TIME:20210211T150000Z UID:https://talks.ox.ac.uk/talks/id/8fbec2d4-39d7-4b8d-bc44-9cb4d40a3562/ DESCRIPTION:\nSpeakers:\nAndreas Larsen (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8fbec2d4-39d7-4b8d-bc44-9cb4d40a3562/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Exploring binding properties of the "lipid-anchors": FYVE and C2 - how to reveal binding strength and orientation by multi-scale MD . - Andreas Larsen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Immersive tools for interactive exploration and manipulation of pr otein-protein interactions - Marc Baaden (French National Centre for Scien tific Research) DTSTART;VALUE=DATE-TIME:20210204T140000Z DTEND;VALUE=DATE-TIME:20210204T150000Z UID:https://talks.ox.ac.uk/talks/id/efd808a0-181c-498f-9adb-02c3e48db9a7/ DESCRIPTION:\nSpeakers:\nMarc Baaden (French National Centre for Scientifi c Research) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/efd808a0-181c-498f-9adb-02c3e48db9a7/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Immersive tools for interactive exploration and manipulat ion of protein-protein interactions - Marc Baaden (French National Centre for Scientific Research) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards a PHIP inhibitor: crystallographic fragment screening and early computational elaboration. - Harold Grosjean (University of Oxford) DTSTART;VALUE=DATE-TIME:20210128T140000Z DTEND;VALUE=DATE-TIME:20210128T150000Z UID:https://talks.ox.ac.uk/talks/id/7fdd742a-2cfc-4067-a738-224a0ccf496d/ DESCRIPTION:\nSpeakers:\nHarold Grosjean (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/81191734541?pwd=TUVsRm 9NVTEvQVRaRGUwb2IvTUFiZz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7fdd742a-2cfc-4067-a738-224a0ccf496d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards a PHIP inhibitor: crystallographic fragment scree ning and early computational elaboration. - Harold Grosjean (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Dynamics of allosteric modulation in NMDA receptors: from molecule s to neurons - Mina Moniri (University of Oxford) DTSTART;VALUE=DATE-TIME:20210121T140000Z DTEND;VALUE=DATE-TIME:20210121T150000Z UID:https://talks.ox.ac.uk/talks/id/999c1e6e-ee7e-43d6-b7b1-c1ec4e66f1db/ DESCRIPTION:\nSpeakers:\nMina Moniri (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/81191734541?pwd=TUVsRm 9NVTEvQVRaRGUwb2IvTUFiZz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/999c1e6e-ee7e-43d6-b7b1-c1ec4e66f1db/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Dynamics of allosteric modulation in NMDA receptors: from molecules to neurons - Mina Moniri (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Understanding conformational ensembles and allostery with biomolec ular simulations - Annie Westerlund (KTH Royal Institute of Technology) DTSTART;VALUE=DATE-TIME:20210114T140000Z DTEND;VALUE=DATE-TIME:20210114T150000Z UID:https://talks.ox.ac.uk/talks/id/9a2cc901-5d22-4f94-8a36-23406ecaf158/ DESCRIPTION:\nSpeakers:\nAnnie Westerlund (KTH Royal Institute of Technolo gy) LOCATION:Held over zoom\, https://us02web.zoom.us/j/81191734541?pwd=TUVsRm 9NVTEvQVRaRGUwb2IvTUFiZz09 contact Robin Corey for more details TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9a2cc901-5d22-4f94-8a36-23406ecaf158/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Understanding conformational ensembles and allostery with biomolecular simulations - Annie Westerlund (KTH Royal Institute of Techn ology) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards coupling structure with function for acid-sensing ion chan nels: initial explorations using the computational microscope - Dr Maria M usgaard (University of Ottowa) DTSTART;VALUE=DATE-TIME:20201203T140000Z DTEND;VALUE=DATE-TIME:20201203T150000Z UID:https://talks.ox.ac.uk/talks/id/15e61c3e-82bb-4742-8cbd-d6d78d3eb4ef/ DESCRIPTION:\nSpeakers:\nDr Maria Musgaard (University of Ottowa) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/15e61c3e-82bb-4742-8cbd-d6d78d3eb4ef/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards coupling structure with function for acid-sensing ion channels: initial explorations using the computational microscope - D r Maria Musgaard (University of Ottowa) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular determinants of cardiolipin signalling in mitochondria - Dr Sarah Rouse (Imperial College London) DTSTART;VALUE=DATE-TIME:20201210T140000Z DTEND;VALUE=DATE-TIME:20201210T150000Z UID:https://talks.ox.ac.uk/talks/id/fcd04c09-445e-4dc1-a54d-6c3673c3d574/ DESCRIPTION:\nSpeakers:\nDr Sarah Rouse (Imperial College London) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fcd04c09-445e-4dc1-a54d-6c3673c3d574/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular determinants of cardiolipin signalling in mitoc hondria - Dr Sarah Rouse (Imperial College London) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Development and Application of Computational Biochemistry - Prof P hil Biggin (University of Oxford) DTSTART;VALUE=DATE-TIME:20201126T140000Z DTEND;VALUE=DATE-TIME:20201126T150000Z UID:https://talks.ox.ac.uk/talks/id/06679325-d535-4a28-aaf6-b6976793fa83/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/06679325-d535-4a28-aaf6-b6976793fa83/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Development and Application of Computational Biochemistry - Prof Phil Biggin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational study of dynamics and catalysis of self-assembled me tallocages. - Dr Tomasz Piskorz (University of Oxford) DTSTART;VALUE=DATE-TIME:20201112T140000Z DTEND;VALUE=DATE-TIME:20201112T150000Z UID:https://talks.ox.ac.uk/talks/id/ccb64cfb-7d88-4adc-820b-4e1def27f001/ DESCRIPTION:\nSpeakers:\nDr Tomasz Piskorz (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ccb64cfb-7d88-4adc-820b-4e1def27f001/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational study of dynamics and catalysis of self-ass embled metallocages. - Dr Tomasz Piskorz (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:cancelled: SBCB seminar - Mina Moniri (University of Oxford) DTSTART;VALUE=DATE-TIME:20201105T140000Z DTEND;VALUE=DATE-TIME:20201105T150000Z UID:https://talks.ox.ac.uk/talks/id/a1024dfb-41f9-41f5-8591-bf8c32c301b2/ DESCRIPTION:\nSpeakers:\nMina Moniri (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a1024dfb-41f9-41f5-8591-bf8c32c301b2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:cancelled: SBCB seminar - Mina Moniri (University of Oxfo rd) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Charlie Cook (University of Oxford) DTSTART;VALUE=DATE-TIME:20201029T140000Z DTEND;VALUE=DATE-TIME:20201029T150000Z UID:https://talks.ox.ac.uk/talks/id/98ef739a-c349-495a-a83e-90002eb940af/ DESCRIPTION:\nSpeakers:\nCharlie Cook (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/98ef739a-c349-495a-a83e-90002eb940af/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Charlie Cook (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computing free energy changes upon protein mutation for protein de sign\, drug resistance\, and mechanism elucidation - Dr Matteo Aldeghi (Ve ctor Institute and University of Toronto) DTSTART;VALUE=DATE-TIME:20201022T140000 DTEND;VALUE=DATE-TIME:20201022T150000 UID:https://talks.ox.ac.uk/talks/id/8f3bec09-5210-4fe6-8f70-de3211999ade/ DESCRIPTION:\nSpeakers:\nDr Matteo Aldeghi (Vector Institute and Universit y of Toronto) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8f3bec09-5210-4fe6-8f70-de3211999ade/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computing free energy changes upon protein mutation for p rotein design\, drug resistance\, and mechanism elucidation - Dr Matteo Al deghi (Vector Institute and University of Toronto) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular dynamics simulations of the SERCA mutant E340A - Maxwell Geurts (University of Oxford) DTSTART;VALUE=DATE-TIME:20201008T140000 DTEND;VALUE=DATE-TIME:20201008T150000 UID:https://talks.ox.ac.uk/talks/id/cf25f3da-6b5b-41b0-b756-d39d6e2837c7/ DESCRIPTION:\nSpeakers:\nMaxwell Geurts (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/cf25f3da-6b5b-41b0-b756-d39d6e2837c7/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular dynamics simulations of the SERCA mutant E340A - Maxwell Geurts (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Influence of Hydrophobicity on Anion Selectivity in Nanopores - Li nda Phan (University of Oxford) DTSTART;VALUE=DATE-TIME:20201015T140000 DTEND;VALUE=DATE-TIME:20201015T150000 UID:https://talks.ox.ac.uk/talks/id/5fd6c319-e110-4bd3-95d8-30e3d9a032db/ DESCRIPTION:\nSpeakers:\nLinda Phan (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5fd6c319-e110-4bd3-95d8-30e3d9a032db/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Influence of Hydrophobicity on Anion Selectivity in Nanop ores - Linda Phan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Professor Mark Sansom (Department of Biochemistry) DTSTART;VALUE=DATE-TIME:20201119T140000Z DTEND;VALUE=DATE-TIME:20201119T150000Z UID:https://talks.ox.ac.uk/talks/id/de12baa0-4e78-4c7a-a2e8-9bc178737dcf/ DESCRIPTION:\nSpeakers:\nProfessor Mark Sansom (Department of Biochemistry ) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/de12baa0-4e78-4c7a-a2e8-9bc178737dcf/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Professor Mark Sansom (Department of Bioch emistry) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:From atomic-resolution ensembles of disordered proteins to simulat ions of tau biomolecular condensates - Dr Lukas Stelzl (Max Planck Institu te of Biophysics) DTSTART;VALUE=DATE-TIME:20200924T140000 DTEND;VALUE=DATE-TIME:20200924T150000 UID:https://talks.ox.ac.uk/talks/id/f7b19745-150d-4a05-a20d-97c7f20c0d40/ DESCRIPTION:\nSpeakers:\nDr Lukas Stelzl (Max Planck Institute of Biophysi cs) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f7b19745-150d-4a05-a20d-97c7f20c0d40/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:From atomic-resolution ensembles of disordered proteins t o simulations of tau biomolecular condensates - Dr Lukas Stelzl (Max Planc k Institute of Biophysics) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Suleyman Cinaroglu (University of Oxford) DTSTART;VALUE=DATE-TIME:20200625T140000 DTEND;VALUE=DATE-TIME:20200625T150000 UID:https://talks.ox.ac.uk/talks/id/c0568956-6d00-4520-95be-051ce375cfd1/ DESCRIPTION:\nSpeakers:\nSuleyman Cinaroglu (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c0568956-6d00-4520-95be-051ce375cfd1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Suleyman Cinaroglu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Zhiyi Wu (University of Oxford) DTSTART;VALUE=DATE-TIME:20200618T140000 DTEND;VALUE=DATE-TIME:20200618T150000 UID:https://talks.ox.ac.uk/talks/id/4c968bfe-1682-44d7-8059-3abd33042a8b/ DESCRIPTION:\nSpeakers:\nZhiyi Wu (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4c968bfe-1682-44d7-8059-3abd33042a8b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Zhiyi Wu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Tanadet Pipatpolkai (University of Oxford) DTSTART;VALUE=DATE-TIME:20200611T140000 DTEND;VALUE=DATE-TIME:20200611T150000 UID:https://talks.ox.ac.uk/talks/id/b569fe4d-7c1f-4611-a692-9c7de664b0cc/ DESCRIPTION:\nSpeakers:\nTanadet Pipatpolkai (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b569fe4d-7c1f-4611-a692-9c7de664b0cc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Tanadet Pipatpolkai (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Professor Syma Khalid (University of Southampton) DTSTART;VALUE=DATE-TIME:20200528T140000 DTEND;VALUE=DATE-TIME:20200528T150000 UID:https://talks.ox.ac.uk/talks/id/5a057a5c-6d0b-4fea-a745-c2a70171c6c2/ DESCRIPTION:\nSpeakers:\nProfessor Syma Khalid (University of Southampton) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5a057a5c-6d0b-4fea-a745-c2a70171c6c2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Professor Syma Khalid (University of South ampton) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Michael Horrell (University of Oxford) DTSTART;VALUE=DATE-TIME:20200521T140000 DTEND;VALUE=DATE-TIME:20200521T150000 UID:https://talks.ox.ac.uk/talks/id/ca3272b1-a983-4a57-91da-472fd978626c/ DESCRIPTION:\nSpeakers:\nMichael Horrell (University of Oxford) LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ca3272b1-a983-4a57-91da-472fd978626c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Michael Horrell (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II talks DTSTART;VALUE=DATE-TIME:20200514T140000 DTEND;VALUE=DATE-TIME:20200514T150000 UID:https://talks.ox.ac.uk/talks/id/2a709658-84f5-413a-adbb-7260151eb66a/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Venue to be announced TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2a709658-84f5-413a-adbb-7260151eb66a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II talks DTSTART;VALUE=DATE-TIME:20200507T140000 DTEND;VALUE=DATE-TIME:20200507T150000 UID:https://talks.ox.ac.uk/talks/id/029883a6-537f-4843-84a5-ef92f6c13c95/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:To be held virtually\, contact host for information TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/029883a6-537f-4843-84a5-ef92f6c13c95/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II talks DTSTART;VALUE=DATE-TIME:20200430T140000 DTEND;VALUE=DATE-TIME:20200430T150000 UID:https://talks.ox.ac.uk/talks/id/254df1a0-f64d-44b3-81fc-bd51689b41e9/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:To be held virtually\, contact host for information TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/254df1a0-f64d-44b3-81fc-bd51689b41e9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB Wellcome Rotation Student talks - Suzanne Letham (University of Oxford)\, Bora Guloglu (University of Oxford) DTSTART;VALUE=DATE-TIME:20200312T140000Z DTEND;VALUE=DATE-TIME:20200312T150000Z UID:https://talks.ox.ac.uk/talks/id/17bc590c-08c1-4180-8442-3fdf32903b2d/ DESCRIPTION:\nSpeakers:\nSuzanne Letham (University of Oxford)\, Bora Gulo glu (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/17bc590c-08c1-4180-8442-3fdf32903b2d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB Wellcome Rotation Student talks - Suzanne Letham (Un iversity of Oxford)\, Bora Guloglu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Could Patched1 function as a cholesterol transporter? - Bertie Ans ell (University of Oxford) DTSTART;VALUE=DATE-TIME:20200305T140000Z DTEND;VALUE=DATE-TIME:20200305T150000Z UID:https://talks.ox.ac.uk/talks/id/53596a3b-45c2-47d1-8317-0b9e34c44143/ DESCRIPTION:\nSpeakers:\nBertie Ansell (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/53596a3b-45c2-47d1-8317-0b9e34c44143/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Could Patched1 function as a cholesterol transporter? - B ertie Ansell (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Predicting Fluoroquinolone Resistance in Mycobacterium tuberculosi s using Alchemical Free Energy Methods - Alice Brankin (Nuffield Departmen t of Medicine\, John Radcliffe Hospital) DTSTART;VALUE=DATE-TIME:20200227T140000Z DTEND;VALUE=DATE-TIME:20200227T150000Z UID:https://talks.ox.ac.uk/talks/id/675be04e-515d-4e0c-ac6b-6b7daecd1adb/ DESCRIPTION:\nSpeakers:\nAlice Brankin (Nuffield Department of Medicine\, John Radcliffe Hospital) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/675be04e-515d-4e0c-ac6b-6b7daecd1adb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Predicting Fluoroquinolone Resistance in Mycobacterium tu berculosis using Alchemical Free Energy Methods - Alice Brankin (Nuffield Department of Medicine\, John Radcliffe Hospital) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Daniel Quetschlich (University of Oxford) DTSTART;VALUE=DATE-TIME:20200130T140000Z DTEND;VALUE=DATE-TIME:20200130T150000Z UID:https://talks.ox.ac.uk/talks/id/e5b2f5c3-c1a9-4059-968f-ff43e93463a8/ DESCRIPTION:\nSpeakers:\nDaniel Quetschlich (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e5b2f5c3-c1a9-4059-968f-ff43e93463a8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Daniel Quetschlich (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part I: GPCR oligomerization: our canonical paradigm of GPCR signa lling may require an evolution. Part II: PyLipID: a versatile analysis to olkit for protein-lipid interactions - Dr Wanling Song (University of Oxfo rd) DTSTART;VALUE=DATE-TIME:20191128T140000Z DTEND;VALUE=DATE-TIME:20191128T150000Z UID:https://talks.ox.ac.uk/talks/id/d538f28d-4ffb-417e-8a67-819ae729de1d/ DESCRIPTION:\nSpeakers:\nDr Wanling Song (University of Oxford) LOCATION:Le Gros Clarke TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d538f28d-4ffb-417e-8a67-819ae729de1d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part I: GPCR oligomerization: our canonical paradigm of G PCR signalling may require an evolution. Part II: PyLipID: a versatile an alysis toolkit for protein-lipid interactions - Dr Wanling Song (Universit y of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Learning from Nature through Computation: From Fundamental Chemist ry to Biological Systems - Fernanda Duarte Gonzalez (University of Oxford) DTSTART;VALUE=DATE-TIME:20200123T140000Z DTEND;VALUE=DATE-TIME:20200123T150000Z UID:https://talks.ox.ac.uk/talks/id/5e2f1ce4-a7be-4ec2-b076-827d73329bf1/ DESCRIPTION:\nSpeakers:\nFernanda Duarte Gonzalez (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5e2f1ce4-a7be-4ec2-b076-827d73329bf1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Learning from Nature through Computation: From Fundamenta l Chemistry to Biological Systems - Fernanda Duarte Gonzalez (University o f Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Structural insights into a mechanosensitive ion channel in carnivo rous plants - Alex Tsui (University of Oxford) DTSTART;VALUE=DATE-TIME:20200116T140000Z DTEND;VALUE=DATE-TIME:20200116T150000Z UID:https://talks.ox.ac.uk/talks/id/25bd14fc-e7db-4164-b759-a2d5a11f6ddc/ DESCRIPTION:\nSpeakers:\nAlex Tsui (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/25bd14fc-e7db-4164-b759-a2d5a11f6ddc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Structural insights into a mechanosensitive ion channel i n carnivorous plants - Alex Tsui (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Free energy simulations of micromolar binders - Dr Irfan Alibay (U niversity of Oxford) DTSTART;VALUE=DATE-TIME:20191212T140000Z DTEND;VALUE=DATE-TIME:20191212T150000Z UID:https://talks.ox.ac.uk/talks/id/fc7e9ffa-0771-406c-bda8-52b5ac800806/ DESCRIPTION:\nSpeakers:\nDr Irfan Alibay (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fc7e9ffa-0771-406c-bda8-52b5ac800806/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Free energy simulations of micromolar binders - Dr Irfan Alibay (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Self-Assembled Floating Supported Membranes - A New Tool for in vi tro Studies on Accurate Model Membranes - Laura John (University of Oxford ) DTSTART;VALUE=DATE-TIME:20191121T140000Z DTEND;VALUE=DATE-TIME:20191121T150000Z UID:https://talks.ox.ac.uk/talks/id/78a64334-33ef-4519-8937-8110c0e958dd/ DESCRIPTION:\nSpeakers:\nLaura John (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (main seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/78a64334-33ef-4519-8937-8110c0e958dd/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Self-Assembled Floating Supported Membranes - A New Tool for in vitro Studies on Accurate Model Membranes - Laura John (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Deep Learning Scoring Function for Flexible Molecular Docking - Ro cco Meli (University of Oxford) DTSTART;VALUE=DATE-TIME:20191114T140000Z DTEND;VALUE=DATE-TIME:20191114T150000Z UID:https://talks.ox.ac.uk/talks/id/4987a849-21c4-44f2-afcf-246149c21af4/ DESCRIPTION:\nSpeakers:\nRocco Meli (University of Oxford) LOCATION:Le Gros Clark Building\, off South Parks Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4987a849-21c4-44f2-afcf-246149c21af4/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Deep Learning Scoring Function for Flexible Molecular Doc king - Rocco Meli (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Investigating LPS insertion in the OM: using molecular dynamics si mulations to complement MS data - Josh Sauer (University of Oxford) DTSTART;VALUE=DATE-TIME:20191107T140000Z DTEND;VALUE=DATE-TIME:20191107T150000Z UID:https://talks.ox.ac.uk/talks/id/f3505e94-900b-4948-8106-21857d14bae4/ DESCRIPTION:\nSpeakers:\nJosh Sauer (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f3505e94-900b-4948-8106-21857d14bae4/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Investigating LPS insertion in the OM: using molecular dy namics simulations to complement MS data - Josh Sauer (University of Oxfor d) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Dissecting the Three-Protein Brain of a Bacterium: E. coli's Chemo sensory Array - Distinguished Professor John S. Parkinson (University of U tah) DTSTART;VALUE=DATE-TIME:20191007T140000 DTEND;VALUE=DATE-TIME:20191007T150000 UID:https://talks.ox.ac.uk/talks/id/186672e6-4851-430c-8630-703b63ee07da/ DESCRIPTION:Motile E. coli cells monitor and track spatial gradients of nu trients in their environment. Their sensing/signaling macinery consists o f transmembrane chemoreceptors networked into a supramolecular signaling a rray by two cytoplasmic protein partners. Concerted genetic\, computation al and structural approaches are revealing the structural and functional o perating principles of this remarkable “brain”.\nSpeakers:\nDistinguis hed Professor John S. Parkinson (University of Utah) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/186672e6-4851-430c-8630-703b63ee07da/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Dissecting the Three-Protein Brain of a Bacterium: E. col i's Chemosensory Array - Distinguished Professor John S. Parkinson (Univer sity of Utah) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Biophysical studies of the pLGIC 9' Leucine gate & determinants of stoichiometric assembly at the adult muscle nAChR - Max Epstein (Universi ty of Oxford) DTSTART;VALUE=DATE-TIME:20191024T140000 DTEND;VALUE=DATE-TIME:20191024T150000 UID:https://talks.ox.ac.uk/talks/id/020b4e6f-d475-45a3-a794-caeb7daad525/ DESCRIPTION:\nSpeakers:\nMax Epstein (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/020b4e6f-d475-45a3-a794-caeb7daad525/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Biophysical studies of the pLGIC 9' Leucine gate & determ inants of stoichiometric assembly at the adult muscle nAChR - Max Epstein (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Professor Mark Sansom (Department of Biochemistry) DTSTART;VALUE=DATE-TIME:20191017T140000 DTEND;VALUE=DATE-TIME:20191017T150000 UID:https://talks.ox.ac.uk/talks/id/a101bab6-c4b2-44b2-a97b-7287a5dc9c9b/ DESCRIPTION:\nSpeakers:\nProfessor Mark Sansom (Department of Biochemistry ) LOCATION:Dorothy Crowfoot Hodgkin Building (main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a101bab6-c4b2-44b2-a97b-7287a5dc9c9b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Professor Mark Sansom (Department of Bioch emistry) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Insights into membrane proteins and drug actions from simulations - Prof Phil Biggin (University of Oxford) DTSTART;VALUE=DATE-TIME:20191010T140000 DTEND;VALUE=DATE-TIME:20191010T150000 UID:https://talks.ox.ac.uk/talks/id/28b5df32-60d6-49b4-9728-d74ac7dd5240/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/28b5df32-60d6-49b4-9728-d74ac7dd5240/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Insights into membrane proteins and drug actions from sim ulations - Prof Phil Biggin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Transmembrane signalling in the E. coli Serine receptor - Keith Ca ssidy (University of Oxford) DTSTART;VALUE=DATE-TIME:20191003T140000 DTEND;VALUE=DATE-TIME:20191003T150000 UID:https://talks.ox.ac.uk/talks/id/d58b0bfa-4146-44de-8bb8-fe7bc3049efc/ DESCRIPTION:\nSpeakers:\nKeith Cassidy (University of Oxford) LOCATION:Le Gros Clark Building\, off South Parks Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d58b0bfa-4146-44de-8bb8-fe7bc3049efc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Transmembrane signalling in the E. coli Serine receptor - Keith Cassidy (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Investigations of protein-lipid interactions in the P-Type ATPase family - Maxwell Geurts (University of Oxford) DTSTART;VALUE=DATE-TIME:20190919T140000 DTEND;VALUE=DATE-TIME:20190919T150000 UID:https://talks.ox.ac.uk/talks/id/0f56f686-7016-4472-b16e-ff9c6925ff0c/ DESCRIPTION:\nSpeakers:\nMaxwell Geurts (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/0f56f686-7016-4472-b16e-ff9c6925ff0c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Investigations of protein-lipid interactions in the P-Typ e ATPase family - Maxwell Geurts (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:How to learn from inconsistencies: integrating molecular simulatio ns with experimental data - Andreas Larsen (University of Oxford) DTSTART;VALUE=DATE-TIME:20190912T140000 DTEND;VALUE=DATE-TIME:20190912T150000 UID:https://talks.ox.ac.uk/talks/id/f74e6a17-2bdb-4a35-94f7-c7d307c6ef26/ DESCRIPTION:\nSpeakers:\nAndreas Larsen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f74e6a17-2bdb-4a35-94f7-c7d307c6ef26/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:How to learn from inconsistencies: integrating molecular simulations with experimental data - Andreas Larsen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Effect of MprF-modified lipids on the adbsorbtion of Antimicrobial Pepties to the Membrane Surface - Patrick Simcock (University of Oxford) DTSTART;VALUE=DATE-TIME:20190718T140000 DTEND;VALUE=DATE-TIME:20190718T150000 UID:https://talks.ox.ac.uk/talks/id/915f4618-e665-4f98-9da3-18e10e507699/ DESCRIPTION:\nSpeakers:\nPatrick Simcock (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/915f4618-e665-4f98-9da3-18e10e507699/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Effect of MprF-modified lipids on the adbsorbtion of Anti microbial Pepties to the Membrane Surface - Patrick Simcock (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:An Unusual Hydrogen-Bond in the KDEL Receptor - Zhiyi Wu (Universi ty of Oxford) DTSTART;VALUE=DATE-TIME:20190711T140000 DTEND;VALUE=DATE-TIME:20190711T150000 UID:https://talks.ox.ac.uk/talks/id/22ba8686-9721-4fba-a18c-0ae836ebc624/ DESCRIPTION:\nSpeakers:\nZhiyi Wu (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/22ba8686-9721-4fba-a18c-0ae836ebc624/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:An Unusual Hydrogen-Bond in the KDEL Receptor - Zhiyi Wu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards coarse-grained simulations of membrane-membrane interfaces - Victor Everett (University of Oxford) DTSTART;VALUE=DATE-TIME:20190627T140000 DTEND;VALUE=DATE-TIME:20190627T150000 UID:https://talks.ox.ac.uk/talks/id/373193af-6c71-4013-831f-175b32d1acea/ DESCRIPTION:\nSpeakers:\nVictor Everett (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/373193af-6c71-4013-831f-175b32d1acea/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards coarse-grained simulations of membrane-membrane i nterfaces - Victor Everett (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Annotating ion channel pores: structures\, hydrophobicity\, and th e threshold for permeation - Shanlin Rao (University of Oxford) DTSTART;VALUE=DATE-TIME:20190613T140000 DTEND;VALUE=DATE-TIME:20190613T150000 UID:https://talks.ox.ac.uk/talks/id/c57e4520-8386-4fc6-bd86-93797d2b7ccd/ DESCRIPTION:\nSpeakers:\nShanlin Rao (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c57e4520-8386-4fc6-bd86-93797d2b7ccd/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Annotating ion channel pores: structures\, hydrophobicity \, and the threshold for permeation - Shanlin Rao (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:From computational to clinical : The story of PIP2 and neonatal di abetes - Tanadet Pipatpolkai (University of Oxford) DTSTART;VALUE=DATE-TIME:20190606T140000 DTEND;VALUE=DATE-TIME:20190606T150000 UID:https://talks.ox.ac.uk/talks/id/4066c771-e0ec-4cbb-9de9-4fabf1093728/ DESCRIPTION:\nSpeakers:\nTanadet Pipatpolkai (University of Oxford) LOCATION:Main Seminar Room TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4066c771-e0ec-4cbb-9de9-4fabf1093728/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:From computational to clinical : The story of PIP2 and ne onatal diabetes - Tanadet Pipatpolkai (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Developing a pipeline for coarse grained simulations of nanodiscs - Michael Horrell (University of Oxford) DTSTART;VALUE=DATE-TIME:20190530T140000 DTEND;VALUE=DATE-TIME:20190530T150000 UID:https://talks.ox.ac.uk/talks/id/add74626-70fb-4166-8d61-4b020e6e470a/ DESCRIPTION:\nSpeakers:\nMichael Horrell (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy)\, off South Parks Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/add74626-70fb-4166-8d61-4b020e6e470a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Developing a pipeline for coarse grained simulations of n anodiscs - Michael Horrell (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Modelling the action of Mycobacterium tuberculosis on macrophage membrane: one mycobacterial lipid at a time - Matthieu Chavent (Institute of Pharmacology and Structural Biology\, Toulouse) DTSTART;VALUE=DATE-TIME:20190523T140000 DTEND;VALUE=DATE-TIME:20190523T150000 UID:https://talks.ox.ac.uk/talks/id/642e731e-efdf-432c-897c-b93227774183/ DESCRIPTION:\nSpeakers:\nMatthieu Chavent (Institute of Pharmacology and S tructural Biology\, Toulouse) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/642e731e-efdf-432c-897c-b93227774183/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Modelling the action of Mycobacterium tuberculosis on ma crophage membrane: one mycobacterial lipid at a time - Matthieu Chavent (I nstitute of Pharmacology and Structural Biology\, Toulouse) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Analytical and computational tools to determine the solution struc ture of protein complexes by small-angle X-ray and neutron scattering - An dreas Larsen (University of Copenhagen) DTSTART;VALUE=DATE-TIME:20190516T140000 DTEND;VALUE=DATE-TIME:20190516T150000 UID:https://talks.ox.ac.uk/talks/id/a8982c23-6503-4cb8-8d25-3e4d0bc69805/ DESCRIPTION:\nSpeakers:\nAndreas Larsen (University of Copenhagen) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a8982c23-6503-4cb8-8d25-3e4d0bc69805/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Analytical and computational tools to determine the solut ion structure of protein complexes by small-angle X-ray and neutron scatte ring - Andreas Larsen (University of Copenhagen) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Effects of lipid complexity in biological membranes: from the nano to the mesoscale - Dr Anna Duncan (University of Oxford) DTSTART;VALUE=DATE-TIME:20190509T140000 DTEND;VALUE=DATE-TIME:20190509T150000 UID:https://talks.ox.ac.uk/talks/id/68c81194-0981-48f8-b5ba-b02fb6ee1bf2/ DESCRIPTION:\nSpeakers:\nDr Anna Duncan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/68c81194-0981-48f8-b5ba-b02fb6ee1bf2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Effects of lipid complexity in biological membranes: from the nano to the mesoscale - Dr Anna Duncan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Cholesterol orientation-dependant modulation of Patched1 extracell ular domain conformation. - Bertie Ansell (University of Oxford) DTSTART;VALUE=DATE-TIME:20190502T140000 DTEND;VALUE=DATE-TIME:20190502T150000 UID:https://talks.ox.ac.uk/talks/id/d09cdfcf-1458-4c47-8946-538abad93f14/ DESCRIPTION:\nSpeakers:\nBertie Ansell (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d09cdfcf-1458-4c47-8946-538abad93f14/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Cholesterol orientation-dependant modulation of Patched1 extracellular domain conformation. - Bertie Ansell (University of Oxfor d) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Jodie Collingridge (University of Oxford)\, Mina Mo niri (University of Oxford) DTSTART;VALUE=DATE-TIME:20190425T140000 DTEND;VALUE=DATE-TIME:20190425T150000 UID:https://talks.ox.ac.uk/talks/id/9ca7e52e-18ef-4cd0-a6a2-a3e8d1b8f459/ DESCRIPTION:\nSpeakers:\nJodie Collingridge (University of Oxford)\, Mina Moniri (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9ca7e52e-18ef-4cd0-a6a2-a3e8d1b8f459/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Jodie Collingridge (University of Oxford)\ , Mina Moniri (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Insights into Membrane Protein-Lipid Interactions from Free Energy Calculations - Dr Robin Corey (University of Oxford) DTSTART;VALUE=DATE-TIME:20190411T140000 DTEND;VALUE=DATE-TIME:20190411T150000 UID:https://talks.ox.ac.uk/talks/id/45155fb8-a3bb-4137-a74b-2993de8b1c9a/ DESCRIPTION:\nSpeakers:\nDr Robin Corey (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/45155fb8-a3bb-4137-a74b-2993de8b1c9a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Insights into Membrane Protein-Lipid Interactions from Fr ee Energy Calculations - Dr Robin Corey (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Assessment of a crystallographic fragment screen using unbiased mo lecular dynamics simulations - Harold Grosjean (University of Oxford) DTSTART;VALUE=DATE-TIME:20190404T140000 DTEND;VALUE=DATE-TIME:20190404T150000 UID:https://talks.ox.ac.uk/talks/id/9bc8bbca-d922-4414-9f5e-c6c7022a52f3/ DESCRIPTION:\nSpeakers:\nHarold Grosjean (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9bc8bbca-d922-4414-9f5e-c6c7022a52f3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Assessment of a crystallographic fragment screen using un biased molecular dynamics simulations - Harold Grosjean (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular Dynamics of a Bacterial S-layer - Dimitrios Kolokouris ( University of Oxford) DTSTART;VALUE=DATE-TIME:20190328T140000Z DTEND;VALUE=DATE-TIME:20190328T150000Z UID:https://talks.ox.ac.uk/talks/id/5fcd8a3e-2999-40b1-8c44-afa4d347bfb5/ DESCRIPTION:\nSpeakers:\nDimitrios Kolokouris (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5fcd8a3e-2999-40b1-8c44-afa4d347bfb5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular Dynamics of a Bacterial S-layer - Dimitrios Kol okouris (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB ACS practice talks - Dr Wanling Song (University of Oxford)\, Dr Charlotte Lynch (University of Oxford) DTSTART;VALUE=DATE-TIME:20190321T140000Z DTEND;VALUE=DATE-TIME:20190321T150000Z UID:https://talks.ox.ac.uk/talks/id/ddab93e9-9637-424d-aaca-117e151088b2/ DESCRIPTION:\nSpeakers:\nDr Wanling Song (University of Oxford)\, Dr Charl otte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ddab93e9-9637-424d-aaca-117e151088b2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB ACS practice talks - Dr Wanling Song (University of Oxford)\, Dr Charlotte Lynch (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II practice talks DTSTART;VALUE=DATE-TIME:20190314T140000Z DTEND;VALUE=DATE-TIME:20190314T150000Z UID:https://talks.ox.ac.uk/talks/id/d12d7596-b279-405d-9013-15877fdc797a/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d12d7596-b279-405d-9013-15877fdc797a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II practice talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB part II practice talks DTSTART;VALUE=DATE-TIME:20190228T140000Z DTEND;VALUE=DATE-TIME:20190228T150000Z UID:https://talks.ox.ac.uk/talks/id/48c436c6-6f12-473f-ac5a-0112631d6738/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/48c436c6-6f12-473f-ac5a-0112631d6738/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB part II practice talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Max Epstein (University of Oxford)\, Dr Anna Duncan (University of Oxford) DTSTART;VALUE=DATE-TIME:20190221T140000Z DTEND;VALUE=DATE-TIME:20190221T150000Z UID:https://talks.ox.ac.uk/talks/id/9b3a7ff1-1c94-4a7d-8fca-a12858180e85/ DESCRIPTION:\nSpeakers:\nMax Epstein (University of Oxford)\, Dr Anna Dunc an (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9b3a7ff1-1c94-4a7d-8fca-a12858180e85/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Max Epstein (University of Oxford)\, Dr An na Duncan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Elizabeth Jefferys (University of Oxford) DTSTART;VALUE=DATE-TIME:20190214T140000Z DTEND;VALUE=DATE-TIME:20190214T150000Z UID:https://talks.ox.ac.uk/talks/id/ea352224-c33c-4207-8738-cffe096958fe/ DESCRIPTION:\nStatus: This talk has been cancelled\n\nSpeakers:\nElizabeth Jefferys (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ea352224-c33c-4207-8738-cffe096958fe/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Elizabeth Jefferys (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Influenza A/M2 clustering causes curvature: an insight to the unde rlying interactions - Iris Kalenderoglou (University of Oxford) DTSTART;VALUE=DATE-TIME:20190207T140000Z DTEND;VALUE=DATE-TIME:20190207T150000Z UID:https://talks.ox.ac.uk/talks/id/925b2cb6-dbf3-44d3-b2cd-8cd0d38fe97e/ DESCRIPTION:\nSpeakers:\nIris Kalenderoglou (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/925b2cb6-dbf3-44d3-b2cd-8cd0d38fe97e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Influenza A/M2 clustering causes curvature: an insight to the underlying interactions - Iris Kalenderoglou (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Owen Vickery (University of Oxford) DTSTART;VALUE=DATE-TIME:20190131T140000Z DTEND;VALUE=DATE-TIME:20190131T150000Z UID:https://talks.ox.ac.uk/talks/id/8250c253-d452-433b-be83-cbfeba7e7709/ DESCRIPTION:\nSpeakers:\nOwen Vickery (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8250c253-d452-433b-be83-cbfeba7e7709/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Owen Vickery (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Structural and computational insights into mechanisms of Apicomple xan perforin-like proteins - Sophie Williams (University of Oxford) DTSTART;VALUE=DATE-TIME:20190124T140000Z DTEND;VALUE=DATE-TIME:20190124T150000Z UID:https://talks.ox.ac.uk/talks/id/128616c7-095b-4f4d-a897-04e77e8d63b2/ DESCRIPTION:\nSpeakers:\nSophie Williams (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/128616c7-095b-4f4d-a897-04e77e8d63b2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Structural and computational insights into mechanisms of Apicomplexan perforin-like proteins - Sophie Williams (University of Oxfor d) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational and native MS studies of β-barrel outer membrane pr otein and LPS biogenesis pathways: emerging structural targets for novel a ntibiotics - Josh Sauer (University of Oxford) DTSTART;VALUE=DATE-TIME:20190117T140000Z DTEND;VALUE=DATE-TIME:20190117T150000Z UID:https://talks.ox.ac.uk/talks/id/7b458449-7a75-4f51-8d4d-34a7ff28546f/ DESCRIPTION:\nSpeakers:\nJosh Sauer (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7b458449-7a75-4f51-8d4d-34a7ff28546f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational and native MS studies of β-barrel outer me mbrane protein and LPS biogenesis pathways: emerging structural targets fo r novel antibiotics - Josh Sauer (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Lipid interactions and ion permeation of a ciliary membrane TRP ch annel\, Polycystin-2 - Qinrui Wang (University of Oxford) DTSTART;VALUE=DATE-TIME:20181206T140000Z DTEND;VALUE=DATE-TIME:20181206T150000Z UID:https://talks.ox.ac.uk/talks/id/02bfc930-1702-437f-9a75-6131df7ba7e3/ DESCRIPTION:\nSpeakers:\nQinrui Wang (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/02bfc930-1702-437f-9a75-6131df7ba7e3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Lipid interactions and ion permeation of a ciliary membra ne TRP channel\, Polycystin-2 - Qinrui Wang (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:GPCR-lipid interactions revealed by MD simulations in in vivo-mime tic membranes - Dr Wanling Song (University of Oxford) DTSTART;VALUE=DATE-TIME:20181129T140000Z DTEND;VALUE=DATE-TIME:20181129T150000Z UID:https://talks.ox.ac.uk/talks/id/71704107-c512-4085-ac89-40cda9c1ecb0/ DESCRIPTION:\nSpeakers:\nDr Wanling Song (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/71704107-c512-4085-ac89-40cda9c1ecb0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:GPCR-lipid interactions revealed by MD simulations in in vivo-mimetic membranes - Dr Wanling Song (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Determining the mechanism behind cholesterol-dependent GPCR signal ing: Simulation and experiment DTSTART;VALUE=DATE-TIME:20181219T150000Z DTEND;VALUE=DATE-TIME:20181219T160000Z UID:https://talks.ox.ac.uk/talks/id/cd1cd2c1-dd5b-424e-aff4-e88e8b355f7e/ DESCRIPTION: LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/cd1cd2c1-dd5b-424e-aff4-e88e8b355f7e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Determining the mechanism behind cholesterol-dependent GP CR signaling: Simulation and experiment TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Adventures in the modelling of bacterial chemosensory arrays - Kei th Cassidy (University of Oxford) DTSTART;VALUE=DATE-TIME:20181213T140000Z DTEND;VALUE=DATE-TIME:20181213T150000Z UID:https://talks.ox.ac.uk/talks/id/d62e3f77-94c7-4299-b178-069357ced74e/ DESCRIPTION:\nSpeakers:\nKeith Cassidy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d62e3f77-94c7-4299-b178-069357ced74e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Adventures in the modelling of bacterial chemosensory arr ays - Keith Cassidy (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Chasing the dragon - Naushad Velgy (University of Oxford) DTSTART;VALUE=DATE-TIME:20181122T140000Z DTEND;VALUE=DATE-TIME:20181122T150000Z UID:https://talks.ox.ac.uk/talks/id/f1f1da7a-39a2-4386-bd6f-70a537c55214/ DESCRIPTION:\nSpeakers:\nNaushad Velgy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f1f1da7a-39a2-4386-bd6f-70a537c55214/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Chasing the dragon - Naushad Velgy (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards Dynamic Pharmacophore Models Through the Use of Coarse Gra ined Molecular Dynamic Simulations - Nick Michelarakis DTSTART;VALUE=DATE-TIME:20181115T140000Z DTEND;VALUE=DATE-TIME:20181115T150000Z UID:https://talks.ox.ac.uk/talks/id/ed9566b5-07de-428f-94ef-979f9e50ce46/ DESCRIPTION:\nSpeakers:\nNick Michelarakis LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ed9566b5-07de-428f-94ef-979f9e50ce46/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards Dynamic Pharmacophore Models Through the Use of C oarse Grained Molecular Dynamic Simulations - Nick Michelarakis TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Hunting the open state of the glycine receptor - Marc Daemgen (Uni versity of Oxford) DTSTART;VALUE=DATE-TIME:20181108T140000Z DTEND;VALUE=DATE-TIME:20181108T150000Z UID:https://talks.ox.ac.uk/talks/id/3697764f-8a7f-4e05-bf15-e74f6b7e9a0b/ DESCRIPTION:\nSpeakers:\nMarc Daemgen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3697764f-8a7f-4e05-bf15-e74f6b7e9a0b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Hunting the open state of the glycine receptor - Marc Dae mgen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Biogenesis Processes within the Bacterial Cell Envelope - Dr Phill ip Stansfeld (University of Oxford) DTSTART;VALUE=DATE-TIME:20181025T140000 DTEND;VALUE=DATE-TIME:20181025T150000 UID:https://talks.ox.ac.uk/talks/id/cf66682a-4150-4f39-9961-436e00e6be75/ DESCRIPTION:\nSpeakers:\nDr Phillip Stansfeld (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/cf66682a-4150-4f39-9961-436e00e6be75/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Biogenesis Processes within the Bacterial Cell Envelope - Dr Phillip Stansfeld (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Simulations of channels\, transporters and drugs - Prof Phil Biggi n (University of Oxford) DTSTART;VALUE=DATE-TIME:20181018T140000 DTEND;VALUE=DATE-TIME:20181018T150000 UID:https://talks.ox.ac.uk/talks/id/adce4383-ab48-4b04-9811-26ad28de3d1a/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/adce4383-ab48-4b04-9811-26ad28de3d1a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Simulations of channels\, transporters and drugs - Prof P hil Biggin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Proteins\, lipids\, water: an overview of research in sansomgroup - Professor Mark Sansom (Department of Biochemistry) DTSTART;VALUE=DATE-TIME:20181011T140000 DTEND;VALUE=DATE-TIME:20181011T150000 UID:https://talks.ox.ac.uk/talks/id/6aaa007c-83dd-4cf0-b115-afcb1aecabbb/ DESCRIPTION:\nSpeakers:\nProfessor Mark Sansom (Department of Biochemistry ) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6aaa007c-83dd-4cf0-b115-afcb1aecabbb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Proteins\, lipids\, water: an overview of research in san somgroup - Professor Mark Sansom (Department of Biochemistry) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular determinants of non-oxime bispyridinium activity at adul t muscle nAChR - Max Epstein (University of Oxford) DTSTART;VALUE=DATE-TIME:20181004T140000 DTEND;VALUE=DATE-TIME:20181004T150000 UID:https://talks.ox.ac.uk/talks/id/1471105a-f773-48dd-8a8b-1fec7bb1112f/ DESCRIPTION:\nSpeakers:\nMax Epstein (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1471105a-f773-48dd-8a8b-1fec7bb1112f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular determinants of non-oxime bispyridinium activit y at adult muscle nAChR - Max Epstein (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards Investigating the Role of the Membrane Environment on the Structure and Function of a Bacterial Potassium Channel - Daniel Quetschli ch (University of Oxford) DTSTART;VALUE=DATE-TIME:20180927T140000 DTEND;VALUE=DATE-TIME:20180927T150000 UID:https://talks.ox.ac.uk/talks/id/7bbb99c9-8b08-4097-a4d9-a97ab2345d69/ DESCRIPTION:\nSpeakers:\nDaniel Quetschlich (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7bbb99c9-8b08-4097-a4d9-a97ab2345d69/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards Investigating the Role of the Membrane Environmen t on the Structure and Function of a Bacterial Potassium Channel - Daniel Quetschlich (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular Dynamics to aid medicinal chemistry: a case study on bro modomains - Joseph Bluck (University of Oxford) DTSTART;VALUE=DATE-TIME:20180920T140000 DTEND;VALUE=DATE-TIME:20180920T150000 UID:https://talks.ox.ac.uk/talks/id/831eaed8-d048-44f4-9935-a7f34239f160/ DESCRIPTION:\nSpeakers:\nJoseph Bluck (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/831eaed8-d048-44f4-9935-a7f34239f160/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular Dynamics to aid medicinal chemistry: a case stu dy on bromodomains - Joseph Bluck (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Multiscale molecular dynamics simulation to explore voltage-gated sodium channel oligomerisation - William Glass (University of Oxford) DTSTART;VALUE=DATE-TIME:20180913T140000 DTEND;VALUE=DATE-TIME:20180913T150000 UID:https://talks.ox.ac.uk/talks/id/e9425cdb-c38d-429d-a65b-0114d755482d/ DESCRIPTION:\nSpeakers:\nWilliam Glass (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e9425cdb-c38d-429d-a65b-0114d755482d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Multiscale molecular dynamics simulation to explore volta ge-gated sodium channel oligomerisation - William Glass (University of Oxf ord) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Membrane Recognition by a Multidomain Protein: A Molecular Simulat ion Study of PTEN and its Constituent Domains - Laura John (University of Oxford) DTSTART;VALUE=DATE-TIME:20180906T140000 DTEND;VALUE=DATE-TIME:20180906T150000 UID:https://talks.ox.ac.uk/talks/id/232b7445-d6e3-4910-a66b-ef47feed14e6/ DESCRIPTION:\nSpeakers:\nLaura John (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/232b7445-d6e3-4910-a66b-ef47feed14e6/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Membrane Recognition by a Multidomain Protein: A Molecula r Simulation Study of PTEN and its Constituent Domains - Laura John (Unive rsity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Re-engineering SAS-6: from spirals to rings - Jodie Ford (Universi ty of Oxford) DTSTART;VALUE=DATE-TIME:20180726T140000 DTEND;VALUE=DATE-TIME:20180726T150000 UID:https://talks.ox.ac.uk/talks/id/8b27229e-2218-4e22-9190-894e12c26b41/ DESCRIPTION:\nSpeakers:\nJodie Ford (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8b27229e-2218-4e22-9190-894e12c26b41/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Re-engineering SAS-6: from spirals to rings - Jodie Ford (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Study of cyclic peptide nanotubes in a membrane environment via Mo lecular Dynamics Simulations - Martin Calvelo (University of Santiago de C ompostela) DTSTART;VALUE=DATE-TIME:20180719T140000 DTEND;VALUE=DATE-TIME:20180719T150000 UID:https://talks.ox.ac.uk/talks/id/38acf9a5-0054-4fd4-a669-97bd59dc340e/ DESCRIPTION:\nSpeakers:\nMartin Calvelo (University of Santiago de Compost ela) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/38acf9a5-0054-4fd4-a669-97bd59dc340e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Study of cyclic peptide nanotubes in a membrane environme nt via Molecular Dynamics Simulations - Martin Calvelo (University of Sant iago de Compostela) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:What Would Water Do? - Hydrophobic Gating of Ion Channels Studied through Atomistic and Polarisable Molecular Dynamics - Gianni Klesse (Univ ersity of Oxford) DTSTART;VALUE=DATE-TIME:20180705T140000 DTEND;VALUE=DATE-TIME:20180705T150000 UID:https://talks.ox.ac.uk/talks/id/eead2ccc-fc8d-4b4d-8897-a081752849c2/ DESCRIPTION:\nSpeakers:\nGianni Klesse (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/eead2ccc-fc8d-4b4d-8897-a081752849c2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:What Would Water Do? - Hydrophobic Gating of Ion Channels Studied through Atomistic and Polarisable Molecular Dynamics - Gianni Kle sse (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Integrating SAXS\, NMR and MD simulations - towards an improved un derstanding of biophysical systems - Tone Bengtsen (University of Oxford) DTSTART;VALUE=DATE-TIME:20180628T140000 DTEND;VALUE=DATE-TIME:20180628T150000 UID:https://talks.ox.ac.uk/talks/id/8b8c88ca-f7ce-4e1b-a8fa-79fb0cb3542b/ DESCRIPTION:\nSpeakers:\nTone Bengtsen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8b8c88ca-f7ce-4e1b-a8fa-79fb0cb3542b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Integrating SAXS\, NMR and MD simulations - towards an im proved understanding of biophysical systems - Tone Bengtsen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Hydrophobic gating in ion channels: A molecular dynamics investiga tion - Shanlin Rao (University of Oxford) DTSTART;VALUE=DATE-TIME:20180517T160000 DTEND;VALUE=DATE-TIME:20180517T170000 UID:https://talks.ox.ac.uk/talks/id/465ca817-cb38-48ba-8cfe-7bfba95bd460/ DESCRIPTION:\nSpeakers:\nShanlin Rao (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/465ca817-cb38-48ba-8cfe-7bfba95bd460/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Hydrophobic gating in ion channels: A molecular dynamics investigation - Shanlin Rao (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Exploring Dynamic Transitions in an Arginine Transporter - Zhiyi W u (University of Oxford) DTSTART;VALUE=DATE-TIME:20180614T140000 DTEND;VALUE=DATE-TIME:20180614T150000 UID:https://talks.ox.ac.uk/talks/id/809b2030-9eef-4e3f-942c-6ee8cfa1b820/ DESCRIPTION:\nSpeakers:\nZhiyi Wu (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/809b2030-9eef-4e3f-942c-6ee8cfa1b820/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Exploring Dynamic Transitions in an Arginine Transporter - Zhiyi Wu (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular dynamics study of biomembrane interactions with biologic ally active polymers - Dr Afroditi-Maria Zaki ( University of Oxford) DTSTART;VALUE=DATE-TIME:20180607T140000 DTEND;VALUE=DATE-TIME:20180607T150000 UID:https://talks.ox.ac.uk/talks/id/6e51e1e0-fc52-4c70-a1c6-aacfa961a699/ DESCRIPTION:\nSpeakers:\nDr Afroditi-Maria Zaki ( University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6e51e1e0-fc52-4c70-a1c6-aacfa961a699/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular dynamics study of biomembrane interactions with biologically active polymers - Dr Afroditi-Maria Zaki ( University of Oxf ord) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Tom Dixon DTSTART;VALUE=DATE-TIME:20180531T140000 DTEND;VALUE=DATE-TIME:20180531T150000 UID:https://talks.ox.ac.uk/talks/id/3e8e1c27-54aa-4e9e-9e98-bd8b5661d101/ DESCRIPTION:\nSpeakers:\nTom Dixon LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3e8e1c27-54aa-4e9e-9e98-bd8b5661d101/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Tom Dixon TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Proton Control of the KDEL Receptor - cancelled - Zhiyi Wu (Univer sity of Oxford) DTSTART;VALUE=DATE-TIME:20210701T140000 DTEND;VALUE=DATE-TIME:20210701T150000 UID:https://talks.ox.ac.uk/talks/id/40a0dad7-d796-4f21-9d37-42bebeea5adc/ DESCRIPTION:\nSpeakers:\nZhiyi Wu (University of Oxford) LOCATION:Held over zoom\, https://us02web.zoom.us/j/87941734423?pwd=bXNiMH U2MnBVVVlSRVBTVlBvMkVydz09 contact Robin Corey for more details - note thi s seminar is now cancelled TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/40a0dad7-d796-4f21-9d37-42bebeea5adc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Proton Control of the KDEL Receptor - cancelled - Zhiyi W u (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:In Touch with Mechanically Activated Piezo Channels via Molecular Dynamics - Che Chun Tsui (University of Oxford) DTSTART;VALUE=DATE-TIME:20180524T140000 DTEND;VALUE=DATE-TIME:20180524T150000 UID:https://talks.ox.ac.uk/talks/id/a6a57c2f-380d-4ccf-8587-31c75a772e30/ DESCRIPTION:\nSpeakers:\nChe Chun Tsui (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a6a57c2f-380d-4ccf-8587-31c75a772e30/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:In Touch with Mechanically Activated Piezo Channels via M olecular Dynamics - Che Chun Tsui (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Mechanosensitive and intracellular pH sensitive of TREK channel - Viwan Jarerattanachat (University of Oxford) DTSTART;VALUE=DATE-TIME:20180503T140000 DTEND;VALUE=DATE-TIME:20180503T150000 UID:https://talks.ox.ac.uk/talks/id/795c1c22-f17a-40e8-855e-6d22e74fc21f/ DESCRIPTION:\nSpeakers:\nViwan Jarerattanachat (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/795c1c22-f17a-40e8-855e-6d22e74fc21f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Mechanosensitive and intracellular pH sensitive of TREK c hannel - Viwan Jarerattanachat (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Calculating NMR Parameters Using Density Functional Theory - Dr Ch arlotte Lynch (University of Oxford) DTSTART;VALUE=DATE-TIME:20180412T140000 DTEND;VALUE=DATE-TIME:20180412T150000 UID:https://talks.ox.ac.uk/talks/id/d38f5552-2055-48fc-9b9e-47e54b6de9fe/ DESCRIPTION:\nSpeakers:\nDr Charlotte Lynch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d38f5552-2055-48fc-9b9e-47e54b6de9fe/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Calculating NMR Parameters Using Density Functional Theor y - Dr Charlotte Lynch (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Using molecular dynamics to add value to cryo-EM structures - Mich ael Horrell (University of Oxford) DTSTART;VALUE=DATE-TIME:20180510T140000 DTEND;VALUE=DATE-TIME:20180510T150000 UID:https://talks.ox.ac.uk/talks/id/1f15685c-89ad-4d90-ad0e-43935cf74a0c/ DESCRIPTION:\nSpeakers:\nMichael Horrell (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1f15685c-89ad-4d90-ad0e-43935cf74a0c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Using molecular dynamics to add value to cryo-EM structur es - Michael Horrell (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Probing conformational landscapes using swarm-enhanced sampling mo lecular dynamics - Dr Irfan Alibay (University of Oxford) DTSTART;VALUE=DATE-TIME:20180405T140000 DTEND;VALUE=DATE-TIME:20180405T150000 UID:https://talks.ox.ac.uk/talks/id/4ed05e91-2b42-4483-a7df-cc52d2381800/ DESCRIPTION:\nSpeakers:\nDr Irfan Alibay (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/4ed05e91-2b42-4483-a7df-cc52d2381800/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Probing conformational landscapes using swarm-enhanced sa mpling molecular dynamics - Dr Irfan Alibay (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II student presentations - Amy Clarke (University of Oxford)\ , Tilly Ansell (University of Oxford)\, Tom Dyer (University of Oxford) DTSTART;VALUE=DATE-TIME:20180315T140000Z DTEND;VALUE=DATE-TIME:20180315T150000Z UID:https://talks.ox.ac.uk/talks/id/f91741aa-0a9e-4f7a-bec4-9a070322ddf9/ DESCRIPTION:\nSpeakers:\nAmy Clarke (University of Oxford)\, Tilly Ansell (University of Oxford)\, Tom Dyer (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f91741aa-0a9e-4f7a-bec4-9a070322ddf9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II student presentations - Amy Clarke (University of Oxford)\, Tilly Ansell (University of Oxford)\, Tom Dyer (University of O xford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Practice talks for Biophysical Society Annual meeting DTSTART;VALUE=DATE-TIME:20180208T140000Z DTEND;VALUE=DATE-TIME:20180208T150000Z UID:https://talks.ox.ac.uk/talks/id/15a917fa-3eba-4396-aff8-8c6632a0e985/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/15a917fa-3eba-4396-aff8-8c6632a0e985/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Practice talks for Biophysical Society Annual meeting TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Pre-protein secretion throught the bacterial Sec translocon - Dr R obin Corey (University of Oxford) DTSTART;VALUE=DATE-TIME:20180322T140000Z DTEND;VALUE=DATE-TIME:20180322T150000Z UID:https://talks.ox.ac.uk/talks/id/2e5f2cf8-ffd3-44aa-a2a2-c6065bff9232/ DESCRIPTION:\nSpeakers:\nDr Robin Corey (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2e5f2cf8-ffd3-44aa-a2a2-c6065bff9232/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Pre-protein secretion throught the bacterial Sec transloc on - Dr Robin Corey (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II student presentations - Amy Kidd (University of Oxford)\, Benjamin Mynors-Wallis (University of Oxford)\, Karan Bali (University of Oxford) DTSTART;VALUE=DATE-TIME:20180308T140000Z DTEND;VALUE=DATE-TIME:20180308T150000Z UID:https://talks.ox.ac.uk/talks/id/533f8526-ceb8-4363-bcfe-11edaa0dcdba/ DESCRIPTION:\nSpeakers:\nAmy Kidd (University of Oxford)\, Benjamin Mynors -Wallis (University of Oxford)\, Karan Bali (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/533f8526-ceb8-4363-bcfe-11edaa0dcdba/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II student presentations - Amy Kidd (University of O xford)\, Benjamin Mynors-Wallis (University of Oxford)\, Karan Bali (Unive rsity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Investigations of the molecular mechanisms driving adenine nucleot ide interactions with the cardiac ryanodine receptor - Chris Lindsay (Univ ersity of Oxford) DTSTART;VALUE=DATE-TIME:20180301T140000Z DTEND;VALUE=DATE-TIME:20180301T150000Z UID:https://talks.ox.ac.uk/talks/id/8803a131-57b1-4abc-b20b-a7002e5d8c10/ DESCRIPTION:\nSpeakers:\nChris Lindsay (University of Oxford) LOCATION:Sherrington Building (Small lecture theatre)\, off Parks Road OX1 3PT TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8803a131-57b1-4abc-b20b-a7002e5d8c10/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Investigations of the molecular mechanisms driving adenin e nucleotide interactions with the cardiac ryanodine receptor - Chris Lind say (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The interplay of sodium and voltage in the regulation of G-protein coupled receptors - Dr Owen Vickery (University of Oxford) DTSTART;VALUE=DATE-TIME:20180201T140000Z DTEND;VALUE=DATE-TIME:20180201T150000Z UID:https://talks.ox.ac.uk/talks/id/f34d8e76-5c3d-4f90-95b2-1e026a33f368/ DESCRIPTION:\nSpeakers:\nDr Owen Vickery (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f34d8e76-5c3d-4f90-95b2-1e026a33f368/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The interplay of sodium and voltage in the regulation of G-protein coupled receptors - Dr Owen Vickery (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:How does Ytterbium Chloride interact with DMPC bilayers? A computa tional study - Dr Miguel A Gonzalez (Universidad Complutense de Madrid) DTSTART;VALUE=DATE-TIME:20180125T140000Z DTEND;VALUE=DATE-TIME:20180125T150000Z UID:https://talks.ox.ac.uk/talks/id/c0f1d49a-9a2f-4394-b793-2ded6e897fa8/ DESCRIPTION:\nSpeakers:\nDr Miguel A Gonzalez (Universidad Complutense de Madrid) LOCATION:Medical Sciences Teaching Centre (Lecture Theatre)\, off South Pa rks Road OX1 3PL TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c0f1d49a-9a2f-4394-b793-2ded6e897fa8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:How does Ytterbium Chloride interact with DMPC bilayers? A computational study - Dr Miguel A Gonzalez (Universidad Complutense de M adrid) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Dynamic organisation of cell membranes from nanoscale to mesoscale - Dr Anna Duncan (University of Oxford) DTSTART;VALUE=DATE-TIME:20171207T140000Z DTEND;VALUE=DATE-TIME:20171207T150000Z UID:https://talks.ox.ac.uk/talks/id/6505f360-beb6-465b-ae1a-1084fc4fe76e/ DESCRIPTION:\nSpeakers:\nDr Anna Duncan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6505f360-beb6-465b-ae1a-1084fc4fe76e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Dynamic organisation of cell membranes from nanoscale to mesoscale - Dr Anna Duncan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The allosteric modulation of lipid on GPCR revealed by MD simulati ons using in vivo-mimetic membranes - Dr Wanling Song (University of Oxfor d) DTSTART;VALUE=DATE-TIME:20171130T140000Z DTEND;VALUE=DATE-TIME:20171130T150000Z UID:https://talks.ox.ac.uk/talks/id/41082c55-65cd-40ea-9c3f-fcfeca1f5cdb/ DESCRIPTION:\nSpeakers:\nDr Wanling Song (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/41082c55-65cd-40ea-9c3f-fcfeca1f5cdb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The allosteric modulation of lipid on GPCR revealed by MD simulations using in vivo-mimetic membranes - Dr Wanling Song (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computing the Bacterial Brain: Molecular dynamics simulations of c hemosensory arrays. - Dr Keith Cassidy (University of Illinois at Urbana-C hampaign) DTSTART;VALUE=DATE-TIME:20171120T100000Z DTEND;VALUE=DATE-TIME:20171120T110000Z UID:https://talks.ox.ac.uk/talks/id/263079d9-abe1-4339-af36-c6fb3bd74d95/ DESCRIPTION:\nSpeakers:\nDr Keith Cassidy (University of Illinois at Urban a-Champaign) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/263079d9-abe1-4339-af36-c6fb3bd74d95/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computing the Bacterial Brain: Molecular dynamics simulat ions of chemosensory arrays. - Dr Keith Cassidy (University of Illinois at Urbana-Champaign) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Simulations of the Glycine Receptor: protein-ligand and protein-li pid interactions - Marc Daemgen (University of Oxford) DTSTART;VALUE=DATE-TIME:20171116T140000Z DTEND;VALUE=DATE-TIME:20171116T150000Z UID:https://talks.ox.ac.uk/talks/id/6a336c45-1f79-41ca-b984-604e74215102/ DESCRIPTION:\nSpeakers:\nMarc Daemgen (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/6a336c45-1f79-41ca-b984-604e74215102/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Simulations of the Glycine Receptor: protein-ligand and p rotein-lipid interactions - Marc Daemgen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:How to Rank a Set of Homology Models and Work in Progress on How t o Accelerate Simulations of Ligand-Induced Conformational Changes - Dr Ole Juul Andersen (University of Oxford) DTSTART;VALUE=DATE-TIME:20171109T140000Z DTEND;VALUE=DATE-TIME:20171109T150000Z UID:https://talks.ox.ac.uk/talks/id/336af50a-0748-4817-8674-33592eb65d10/ DESCRIPTION:\nSpeakers:\nDr Ole Juul Andersen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/336af50a-0748-4817-8674-33592eb65d10/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:How to Rank a Set of Homology Models and Work in Progress on How to Accelerate Simulations of Ligand-Induced Conformational Changes - Dr Ole Juul Andersen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational Biochemistry of Biogenesis\, Assembly & Transport at the Membrane - Dr Phillip Stansfeld (University of Oxford) DTSTART;VALUE=DATE-TIME:20171102T140000Z DTEND;VALUE=DATE-TIME:20171102T150000Z UID:https://talks.ox.ac.uk/talks/id/5c560bbe-23a9-4c3a-af8e-a3aa40d37748/ DESCRIPTION:\nSpeakers:\nDr Phillip Stansfeld (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5c560bbe-23a9-4c3a-af8e-a3aa40d37748/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational Biochemistry of Biogenesis\, Assembly & Tra nsport at the Membrane - Dr Phillip Stansfeld (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Are simulations predictive? Some recent case studies on iGluRs an d Bromodomains - Prof Phil Biggin (University of Oxford) DTSTART;VALUE=DATE-TIME:20171019T140000 DTEND;VALUE=DATE-TIME:20171019T150000 UID:https://talks.ox.ac.uk/talks/id/8ab56cdb-870f-427c-a7bc-164e999d8a9a/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8ab56cdb-870f-427c-a7bc-164e999d8a9a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Are simulations predictive? Some recent case studies on iGluRs and Bromodomains - Prof Phil Biggin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:A PIP2 Binding Site on a Human TRP Channel: Simulation Studies of PKD2 - Qinrui Wang (University of Oxford) DTSTART;VALUE=DATE-TIME:20170928T140000 DTEND;VALUE=DATE-TIME:20170928T150000 UID:https://talks.ox.ac.uk/talks/id/c8fcbf9a-7bef-4c39-9d9e-4dd20b35805b/ DESCRIPTION:\nSpeakers:\nQinrui Wang (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c8fcbf9a-7bef-4c39-9d9e-4dd20b35805b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:A PIP2 Binding Site on a Human TRP Channel: Simulation S tudies of PKD2 - Qinrui Wang (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Linking proton sensors and channel motions in acid-sensing ion cha nnels - Dr Maria Musgaard (University of Oxford) DTSTART;VALUE=DATE-TIME:20171123T140000Z DTEND;VALUE=DATE-TIME:20171123T150000Z UID:https://talks.ox.ac.uk/talks/id/38a7d3b8-f684-4b14-acde-1cfc0f4773c0/ DESCRIPTION:\nSpeakers:\nDr Maria Musgaard (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/38a7d3b8-f684-4b14-acde-1cfc0f4773c0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Linking proton sensors and channel motions in acid-sensin g ion channels - Dr Maria Musgaard (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards multiscale modelling of virus-cell interactions at the mem brane - Elizabeth Jefferys (University of Oxford) DTSTART;VALUE=DATE-TIME:20171026T140000 DTEND;VALUE=DATE-TIME:20171026T150000 UID:https://talks.ox.ac.uk/talks/id/913816c5-6324-4b37-a98e-0bbe443dba95/ DESCRIPTION:\nSpeakers:\nElizabeth Jefferys (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/913816c5-6324-4b37-a98e-0bbe443dba95/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards multiscale modelling of virus-cell interactions a t the membrane - Elizabeth Jefferys (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Oil and Water: simulations of membranes\, lipids\, channels etc. - Professor Mark Sansom (Department of Biochemistry) DTSTART;VALUE=DATE-TIME:20171012T140000 DTEND;VALUE=DATE-TIME:20171012T150000 UID:https://talks.ox.ac.uk/talks/id/2e11fcf0-4d88-4b0f-a714-cbf2ca8842d0/ DESCRIPTION:\nSpeakers:\nProfessor Mark Sansom (Department of Biochemistry ) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2e11fcf0-4d88-4b0f-a714-cbf2ca8842d0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Oil and Water: simulations of membranes\, lipids\, channe ls etc. - Professor Mark Sansom (Department of Biochemistry) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Characterising Drug Binding to the Cardiomyocyte K+ Ion Channel\, hERG (Kv11.1) - Matt Raybould (University of Oxford) DTSTART;VALUE=DATE-TIME:20171005T140000 DTEND;VALUE=DATE-TIME:20171005T150000 UID:https://talks.ox.ac.uk/talks/id/bc0bbee6-d09e-4b31-899a-962c365fe6b3/ DESCRIPTION:\nSpeakers:\nMatt Raybould (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/bc0bbee6-d09e-4b31-899a-962c365fe6b3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Characterising Drug Binding to the Cardiomyocyte K+ Ion C hannel\, hERG (Kv11.1) - Matt Raybould (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Modelling bacterial lipoproteins - George Bates (University of Oxf ord) DTSTART;VALUE=DATE-TIME:20170921T140000 DTEND;VALUE=DATE-TIME:20170921T150000 UID:https://talks.ox.ac.uk/talks/id/fe23896b-cd7f-409d-874a-94221754b061/ DESCRIPTION:\nSpeakers:\nGeorge Bates (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fe23896b-cd7f-409d-874a-94221754b061/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Modelling bacterial lipoproteins - George Bates (Universi ty of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Building a pore: Apicomplexan pore forming proteins and their inte ractions with membranes - Sophie Williams (University of Oxford) DTSTART;VALUE=DATE-TIME:20170824T140000 DTEND;VALUE=DATE-TIME:20170824T150000 UID:https://talks.ox.ac.uk/talks/id/0e23ee64-520a-4dcd-b8c2-1b3f3031d2b9/ DESCRIPTION:\nSpeakers:\nSophie Williams (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/0e23ee64-520a-4dcd-b8c2-1b3f3031d2b9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Building a pore: Apicomplexan pore forming proteins and t heir interactions with membranes - Sophie Williams (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Functional Annotation of Ion Channel Structures by Molecular Dynam ics Simulation - Gianni Klesse (University of Oxford) DTSTART;VALUE=DATE-TIME:20170803T140000 DTEND;VALUE=DATE-TIME:20170803T150000 UID:https://talks.ox.ac.uk/talks/id/63a9a8c9-6858-4eee-8e84-085218557769/ DESCRIPTION:\nSpeakers:\nGianni Klesse (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/63a9a8c9-6858-4eee-8e84-085218557769/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Functional Annotation of Ion Channel Structures by Molecu lar Dynamics Simulation - Gianni Klesse (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:A multi-pronged approach to targeting GPR40 for diabetes - Dr Jenn ifer Johnston (Merck\, USA) DTSTART;VALUE=DATE-TIME:20170907T140000 DTEND;VALUE=DATE-TIME:20170907T150000 UID:https://talks.ox.ac.uk/talks/id/00926b23-9d44-4edf-801a-95c392c8f042/ DESCRIPTION:Here we chart the quest to agonize GPR40 (FFAR1)\, the G prote in-coupled medium to long chain free fatty acid receptor\, as a possible m echanism for the treatment of Type II Diabetes Mellitus. Clinical studies indicate that partial agonists of GPR40\, e.g. MK-8666\, enhance glucose-d ependent insulin secretion. A single crystal structure of GPR40 with MK-86 66 shone a spotlight on partial agonism\, and rationalized the SAR around MK-8666.\n\nExploring the multiple activation mechanisms of GPR40 led to t he discovery of a second class of compounds\, AgoPAMs. Pre-clinical studie s indicate that AgoPAMs can behave both as full agonists of GPR40 and allo steric modulators of partial agonists\, and can provide additional efficac y through gut-driven incretin secretion. Using only the crystal structure of the partial agonist-bound receptor for guidance for this new class of c ompounds proved to be misleading\, and it was apparent that we needed new insights. A second crystal structure with both an AgoPAM and a partial ag onist bound shone new light on the project\, providing key mechanistic and SAR understandings that could guide both compound and pre-clinical study design.\n\nIn summary\, structure enablement for GPR40 has provided gradu al illumination of the pathway to the clinic for GPR40 agonists and has hi ghlighted some general lessons for structure-based drug design on GPCRs al ong the way\, most notably: that we should not be surprised when diverse l igand profiles are matched by diverse binding sites\, and that extensive m utagenesis and more than one crystal structure are essential for a clearer understanding of these ubiquitous and vital receptors.\nSpeakers:\nDr Jen nifer Johnston (Merck\, USA) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/00926b23-9d44-4edf-801a-95c392c8f042/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:A multi-pronged approach to targeting GPR40 for diabetes - Dr Jennifer Johnston (Merck\, USA) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Determining the mechanism of action of bispyridinium compounds for the treatment of nerve agent exposure - Max Epstein (University of Oxford ) DTSTART;VALUE=DATE-TIME:20170720T140000 DTEND;VALUE=DATE-TIME:20170720T150000 UID:https://talks.ox.ac.uk/talks/id/b10dddbb-1373-45a6-981b-da77b0e9c5da/ DESCRIPTION:\nSpeakers:\nMax Epstein (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/b10dddbb-1373-45a6-981b-da77b0e9c5da/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Determining the mechanism of action of bispyridinium comp ounds for the treatment of nerve agent exposure - Max Epstein (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:DNA nanotubes and their interaction with membranes: Insights throu gh multiscale molecular dynamics simulations - Dr Vishal Maingi (Universit y of Oxford) DTSTART;VALUE=DATE-TIME:20170615T140000 DTEND;VALUE=DATE-TIME:20170615T150000 UID:https://talks.ox.ac.uk/talks/id/8ed94ce1-f652-45b6-9de3-715665331b45/ DESCRIPTION:\nSpeakers:\nDr Vishal Maingi (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8ed94ce1-f652-45b6-9de3-715665331b45/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:DNA nanotubes and their interaction with membranes: Insig hts through multiscale molecular dynamics simulations - Dr Vishal Maingi ( University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB Seminar - Daniel Quetschlich (University of Oxford)\, Georgia Oakley (University of Oxford) DTSTART;VALUE=DATE-TIME:20170706T140000 DTEND;VALUE=DATE-TIME:20170706T150000 UID:https://talks.ox.ac.uk/talks/id/1f500404-3b95-496e-8539-eda85944f983/ DESCRIPTION:\nSpeakers:\nDaniel Quetschlich (University of Oxford)\, Georg ia Oakley (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1f500404-3b95-496e-8539-eda85944f983/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB Seminar - Daniel Quetschlich (University of Oxford)\ , Georgia Oakley (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Closed\, open\, or 'maybe open': Annotating ion channel structures by molecular simulation - Shanlin Rao (University of Oxford) DTSTART;VALUE=DATE-TIME:20170629T140000 DTEND;VALUE=DATE-TIME:20170629T150000 UID:https://talks.ox.ac.uk/talks/id/e536ddc7-bbab-4123-a3b5-890359a3a145/ DESCRIPTION:\nSpeakers:\nShanlin Rao (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e536ddc7-bbab-4123-a3b5-890359a3a145/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Closed\, open\, or 'maybe open': Annotating ion channel s tructures by molecular simulation - Shanlin Rao (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Using contact maps to drive GPCR conformation - Naushad Velgy (Uni versity of Oxford) DTSTART;VALUE=DATE-TIME:20170622T140000 DTEND;VALUE=DATE-TIME:20170622T150000 UID:https://talks.ox.ac.uk/talks/id/597eb236-5150-4735-8031-344ad3b8e1ba/ DESCRIPTION:\nSpeakers:\nNaushad Velgy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/597eb236-5150-4735-8031-344ad3b8e1ba/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Using contact maps to drive GPCR conformation - Naushad V elgy (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Multiscale Simulations of Membrane Recognition by Lipid Kinases - Sarah-Beth Amos (University of Oxford) DTSTART;VALUE=DATE-TIME:20170608T140000 DTEND;VALUE=DATE-TIME:20170608T150000 UID:https://talks.ox.ac.uk/talks/id/d64037a6-b00b-4353-81cc-d69825184704/ DESCRIPTION:\nSpeakers:\nSarah-Beth Amos (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d64037a6-b00b-4353-81cc-d69825184704/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Multiscale Simulations of Membrane Recognition by Lipid K inases - Sarah-Beth Amos (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Protein engineering of SAS-6: from spirals to cartwheels - Jodie F ord (University of Oxford) DTSTART;VALUE=DATE-TIME:20170601T140000 DTEND;VALUE=DATE-TIME:20170601T150000 UID:https://talks.ox.ac.uk/talks/id/f93a2d1e-bf3a-463a-bf8d-846a773da6da/ DESCRIPTION:\nSpeakers:\nJodie Ford (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f93a2d1e-bf3a-463a-bf8d-846a773da6da/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Protein engineering of SAS-6: from spirals to cartwheels - Jodie Ford (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Dynamic organisation of crowded and complex cell membranes - Dr An na Duncan (University of Oxford) DTSTART;VALUE=DATE-TIME:20170525T140000 DTEND;VALUE=DATE-TIME:20170525T150000 UID:https://talks.ox.ac.uk/talks/id/a02103a4-7686-4bda-9649-6946d2bf5e68/ DESCRIPTION:\nSpeakers:\nDr Anna Duncan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a02103a4-7686-4bda-9649-6946d2bf5e68/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Dynamic organisation of crowded and complex cell membrane s - Dr Anna Duncan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Nonspecific porins: the passive regulators on Gram-negative bacter ia outer-membranes - Dr Wanling Song (University of Oxford) DTSTART;VALUE=DATE-TIME:20170518T140000 DTEND;VALUE=DATE-TIME:20170518T150000 UID:https://talks.ox.ac.uk/talks/id/f64cd21a-b96a-4849-b169-840096cb9521/ DESCRIPTION:\nSpeakers:\nDr Wanling Song (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f64cd21a-b96a-4849-b169-840096cb9521/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Nonspecific porins: the passive regulators on Gram-negati ve bacteria outer-membranes - Dr Wanling Song (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Towards Dynamic Pharmacophore Models Through the Use of CG-MD Simu lations. Are We Nearly There Yet? - Nicholas Michelarakis (University of O xford) DTSTART;VALUE=DATE-TIME:20170511T140000 DTEND;VALUE=DATE-TIME:20170511T150000 UID:https://talks.ox.ac.uk/talks/id/fa4f74af-5c55-4f1f-b832-6b092d128b5c/ DESCRIPTION:\nSpeakers:\nNicholas Michelarakis (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fa4f74af-5c55-4f1f-b832-6b092d128b5c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Towards Dynamic Pharmacophore Models Through the Use of C G-MD Simulations. Are We Nearly There Yet? - Nicholas Michelarakis (Univer sity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Combining functional and computational approaches to describe the GluK2/GluK5 heterotetramer gating mechanism - Dr Teresa Paramo Prieto (Uni versity of Oxford) DTSTART;VALUE=DATE-TIME:20170504T140000 DTEND;VALUE=DATE-TIME:20170504T150000 UID:https://talks.ox.ac.uk/talks/id/27e45849-7d04-4ea3-93df-675c83707975/ DESCRIPTION:\nSpeakers:\nDr Teresa Paramo Prieto (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/27e45849-7d04-4ea3-93df-675c83707975/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Combining functional and computational approaches to desc ribe the GluK2/GluK5 heterotetramer gating mechanism - Dr Teresa Paramo Pr ieto (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Anomalous Diffusion in Artificial Lipid Bilayers - Dr Matthew Chee tham (King's College London) DTSTART;VALUE=DATE-TIME:20170427T140000 DTEND;VALUE=DATE-TIME:20170427T150000 UID:https://talks.ox.ac.uk/talks/id/62beb407-9386-4750-a681-ec2a61a449a6/ DESCRIPTION:\nSpeakers:\nDr Matthew Cheetham (King's College London) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/62beb407-9386-4750-a681-ec2a61a449a6/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Anomalous Diffusion in Artificial Lipid Bilayers - Dr Mat thew Cheetham (King's College London) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:"Molecular dynamics investigation of prolipoprotein Diacylglyceryl Transferase (Lgt)" and "Hydrogen bonds and water bridges: How does PepTho m stabilise Valacyclovir in its binding pose" - Zhiyi Wu (University of Ox ford)\, Mabel Wong (University of Oxford) DTSTART;VALUE=DATE-TIME:20170406T140000 DTEND;VALUE=DATE-TIME:20170406T150000 UID:https://talks.ox.ac.uk/talks/id/9f1da329-ff1f-47a3-a289-7e07842dcc02/ DESCRIPTION:\nSpeakers:\nZhiyi Wu (University of Oxford)\, Mabel Wong (Uni versity of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9f1da329-ff1f-47a3-a289-7e07842dcc02/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:"Molecular dynamics investigation of prolipoprotein Diacy lglyceryl Transferase (Lgt)" and "Hydrogen bonds and water bridges: How do es PepThom stabilise Valacyclovir in its binding pose" - Zhiyi Wu (Univers ity of Oxford)\, Mabel Wong (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:On the lesser known uses of umbrellas: investigating interactions of PH domains with membranes through umbrella sampling - Fiona Naughton (U niversity of Oxford) DTSTART;VALUE=DATE-TIME:20170330T140000 DTEND;VALUE=DATE-TIME:20170330T150000 UID:https://talks.ox.ac.uk/talks/id/fd18b910-faaa-4e63-a58a-fd6289f6f082/ DESCRIPTION:\nSpeakers:\nFiona Naughton (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/fd18b910-faaa-4e63-a58a-fd6289f6f082/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:On the lesser known uses of umbrellas: investigating inte ractions of PH domains with membranes through umbrella sampling - Fiona Na ughton (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:A new web interface for the MemProtMD database - Tom Newport (Univ ersity of Oxford) DTSTART;VALUE=DATE-TIME:20170323T140000Z DTEND;VALUE=DATE-TIME:20170323T150000Z UID:https://talks.ox.ac.uk/talks/id/787bbb4c-cf8f-443a-8a88-6c725b642d8a/ DESCRIPTION:\nSpeakers:\nTom Newport (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/787bbb4c-cf8f-443a-8a88-6c725b642d8a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:A new web interface for the MemProtMD database - Tom Newp ort (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Mechanosensation: from MscL to TREK-2 - Viwan Jarerattanachat (Uni versity of Oxford) DTSTART;VALUE=DATE-TIME:20170309T140000Z DTEND;VALUE=DATE-TIME:20170309T150000Z UID:https://talks.ox.ac.uk/talks/id/7d03407c-7d5b-4d61-9b39-426935232f5d/ DESCRIPTION:\nSpeakers:\nViwan Jarerattanachat (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7d03407c-7d5b-4d61-9b39-426935232f5d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Mechanosensation: from MscL to TREK-2 - Viwan Jarerattana chat (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:P-glycoprotein interactions with drugs and lipids - Dr Laura Domic evica (University of Oxford) DTSTART;VALUE=DATE-TIME:20170302T140000Z DTEND;VALUE=DATE-TIME:20170302T150000Z UID:https://talks.ox.ac.uk/talks/id/85c34536-1f64-4281-a842-8862b0007e9c/ DESCRIPTION:\nSpeakers:\nDr Laura Domicevica (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/85c34536-1f64-4281-a842-8862b0007e9c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:P-glycoprotein interactions with drugs and lipids - Dr La ura Domicevica (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Part II talks DTSTART;VALUE=DATE-TIME:20170223T140000Z DTEND;VALUE=DATE-TIME:20170223T150000Z UID:https://talks.ox.ac.uk/talks/id/da4bcaff-b1bc-4587-9098-ad1d397fad6f/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/da4bcaff-b1bc-4587-9098-ad1d397fad6f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Part II talks TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Talks for Biophysics - Fiona Naughton (University o f Oxford)\, Dr Anna Duncan (University of Oxford) DTSTART;VALUE=DATE-TIME:20170202T140000Z DTEND;VALUE=DATE-TIME:20170202T150000Z UID:https://talks.ox.ac.uk/talks/id/d44deab7-5b91-42ab-a6c6-855e48f9dc38/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d44deab7-5b91-42ab-a6c6-855e48f9dc38/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Talks for Biophysics - Fiona Naughton (Uni versity of Oxford)\, Dr Anna Duncan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular Dynamics Studies of the GABAA Ion Channel Receptor - Dr Ole Juul Andersen (University of Oxford) DTSTART;VALUE=DATE-TIME:20170126T140000Z DTEND;VALUE=DATE-TIME:20170126T150000Z UID:https://talks.ox.ac.uk/talks/id/3c1481d9-2c89-4eb9-a13f-7146f286ecc2/ DESCRIPTION:\nSpeakers:\nDr Ole Juul Andersen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3c1481d9-2c89-4eb9-a13f-7146f286ecc2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular Dynamics Studies of the GABAA Ion Channel Recep tor - Dr Ole Juul Andersen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Confirm or deny: converged association energies for membrane helix -helix dimers - Jan Domanski (University of Oxford) DTSTART;VALUE=DATE-TIME:20170119T140000Z DTEND;VALUE=DATE-TIME:20170119T150000Z UID:https://talks.ox.ac.uk/talks/id/546a5944-ab75-4e9d-9a14-4b83b3193b7d/ DESCRIPTION:\nSpeakers:\nJan Domanski (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/546a5944-ab75-4e9d-9a14-4b83b3193b7d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Confirm or deny: converged association energies for membr ane helix-helix dimers - Jan Domanski (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Deregulation of Osmoregulatory Machinery Controls Cellular Transfo rmation in Cancer and Disease - Dr David Shorthouse (MRC Cancer Unit\, Uni versity of Cambridge) DTSTART;VALUE=DATE-TIME:20161027T140000 DTEND;VALUE=DATE-TIME:20161027T150000 UID:https://talks.ox.ac.uk/talks/id/40c3f055-ad84-40e9-a57e-b9021844a54f/ DESCRIPTION:\nSpeakers:\nDr David Shorthouse (MRC Cancer Unit\, University of Cambridge) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/40c3f055-ad84-40e9-a57e-b9021844a54f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Deregulation of Osmoregulatory Machinery Controls Cellula r Transformation in Cancer and Disease - Dr David Shorthouse (MRC Cancer U nit\, University of Cambridge) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Multiscale simulations of peripheral membrane proteins: unravellin g the details of how PIP kinases recognise and bind to their lipid substra tes - Sarah-Beth Amos (University of Oxford) DTSTART;VALUE=DATE-TIME:20160915T140000 DTEND;VALUE=DATE-TIME:20160915T150000 UID:https://talks.ox.ac.uk/talks/id/2a61e080-a1b9-431a-adae-f7fa3373f6be/ DESCRIPTION:\nSpeakers:\nSarah-Beth Amos (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2a61e080-a1b9-431a-adae-f7fa3373f6be/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Multiscale simulations of peripheral membrane proteins: u nravelling the details of how PIP kinases recognise and bind to their lipi d substrates - Sarah-Beth Amos (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:MD Simulations of the Glycine Receptor - Marc Daemgen (University of Oxford) DTSTART;VALUE=DATE-TIME:20161124T140000Z DTEND;VALUE=DATE-TIME:20161124T150000Z UID:https://talks.ox.ac.uk/talks/id/7bbe919a-944e-44bd-ae51-a1a8e485ef0d/ DESCRIPTION:\nSpeakers:\nMarc Daemgen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7bbe919a-944e-44bd-ae51-a1a8e485ef0d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:MD Simulations of the Glycine Receptor - Marc Daemgen (Un iversity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:From the nano to the mesoscale: filling the gap between computatio ns and experiments - Dr Matthieu Chavent (University of Oxford) DTSTART;VALUE=DATE-TIME:20161117T140000Z DTEND;VALUE=DATE-TIME:20161117T150000Z UID:https://talks.ox.ac.uk/talks/id/1e61ac2f-5502-435c-8bf5-d5a6136a286b/ DESCRIPTION:\nSpeakers:\nDr Matthieu Chavent (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1e61ac2f-5502-435c-8bf5-d5a6136a286b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:From the nano to the mesoscale: filling the gap between c omputations and experiments - Dr Matthieu Chavent (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Characterising lipid-protein interactions through computational mo delling - George Hedger (University of Oxford) DTSTART;VALUE=DATE-TIME:20161110T140000Z DTEND;VALUE=DATE-TIME:20161110T150000Z UID:https://talks.ox.ac.uk/talks/id/e4d30bc9-facb-4230-947c-17a72c639937/ DESCRIPTION:\nSpeakers:\nGeorge Hedger (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/e4d30bc9-facb-4230-947c-17a72c639937/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Characterising lipid-protein interactions through computa tional modelling - George Hedger (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Bridging the gap: Explaining and guiding experiments on ligand-gat ed ion channels using computational modelling - Dr Maria Musgaard (Univers ity of Oxford) DTSTART;VALUE=DATE-TIME:20161103T140000Z DTEND;VALUE=DATE-TIME:20161103T150000Z UID:https://talks.ox.ac.uk/talks/id/85230af7-8b58-421d-b0fb-1149d6a73e1b/ DESCRIPTION:\nSpeakers:\nDr Maria Musgaard (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/85230af7-8b58-421d-b0fb-1149d6a73e1b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Bridging the gap: Explaining and guiding experiments on l igand-gated ion channels using computational modelling - Dr Maria Musgaard (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Modelling and Dynamics of Molecular Processes at the Membrane - Dr Phillip Stansfeld (University of Oxford) DTSTART;VALUE=DATE-TIME:20161208T140000Z DTEND;VALUE=DATE-TIME:20161208T150000Z UID:https://talks.ox.ac.uk/talks/id/17a36147-3cc0-4852-9727-8494ba26f256/ DESCRIPTION:\nSpeakers:\nDr Phillip Stansfeld (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/17a36147-3cc0-4852-9727-8494ba26f256/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Modelling and Dynamics of Molecular Processes at the Memb rane - Dr Phillip Stansfeld (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Five years of computational virology - Dr Tyler Reddy (University of Oxford) DTSTART;VALUE=DATE-TIME:20161020T140000 DTEND;VALUE=DATE-TIME:20161020T150000 UID:https://talks.ox.ac.uk/talks/id/d9d9084e-7657-4ffa-a68c-d1bee23d5e78/ DESCRIPTION:\nSpeakers:\nDr Tyler Reddy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d9d9084e-7657-4ffa-a68c-d1bee23d5e78/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Five years of computational virology - Dr Tyler Reddy (Un iversity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Membrane protein interactions with lipids\; cell surface receptors \; ion channels\; & nanopores: an overview of membrane simulation studies - Professor Mark Sansom (Department of Biochemistry) DTSTART;VALUE=DATE-TIME:20161013T140000 DTEND;VALUE=DATE-TIME:20161013T150000 UID:https://talks.ox.ac.uk/talks/id/3422584a-32ec-44ed-b4e5-7ff9c78cb6ef/ DESCRIPTION:\nSpeakers:\nProfessor Mark Sansom (Department of Biochemistry ) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3422584a-32ec-44ed-b4e5-7ff9c78cb6ef/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Membrane protein interactions with lipids\; cell surface receptors\; ion channels\; & nanopores: an overview of membrane simulation studies - Professor Mark Sansom (Department of Biochemistry) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:How simulation can complement experiments - Prof Phil Biggin (Univ ersity of Oxford) DTSTART;VALUE=DATE-TIME:20161006T140000 DTEND;VALUE=DATE-TIME:20161006T150000 UID:https://talks.ox.ac.uk/talks/id/d6c0dd15-731f-4bcc-8161-9235ba2834a1/ DESCRIPTION:\nSpeakers:\nProf Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d6c0dd15-731f-4bcc-8161-9235ba2834a1/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:How simulation can complement experiments - Prof Phil Big gin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Gianni Klesse (University of Oxford)\, Joseph Bluck (University of Oxford)\, Bartosz Bartmanski (University of Oxford) DTSTART;VALUE=DATE-TIME:20160929T140000 DTEND;VALUE=DATE-TIME:20160929T150000 UID:https://talks.ox.ac.uk/talks/id/c713b18e-1a86-4f8a-aca2-e6d338aa0f53/ DESCRIPTION:\nSpeakers:\n Various Speakers LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c713b18e-1a86-4f8a-aca2-e6d338aa0f53/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Gianni Klesse (University of Oxford)\, Jos eph Bluck (University of Oxford)\, Bartosz Bartmanski (University of Oxfor d) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Opioids in their pocket - Naushad Velgy (University of Oxford) DTSTART;VALUE=DATE-TIME:20160922T140000 DTEND;VALUE=DATE-TIME:20160922T150000 UID:https://talks.ox.ac.uk/talks/id/aa8c8933-a701-43d8-9fea-794167e8dfd5/ DESCRIPTION:\nSpeakers:\nNaushad Velgy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/aa8c8933-a701-43d8-9fea-794167e8dfd5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Opioids in their pocket - Naushad Velgy (University of Ox ford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Homology Modelling and Molecular Dynamics Simulation of a ClC-5 `G ating' Mutation - Linus Conrad (University of Oxford) DTSTART;VALUE=DATE-TIME:20160908T140000 DTEND;VALUE=DATE-TIME:20160908T150000 UID:https://talks.ox.ac.uk/talks/id/48ef0d0c-db34-43d6-ab4e-90c581fbbf41/ DESCRIPTION:\nSpeakers:\nLinus Conrad (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/48ef0d0c-db34-43d6-ab4e-90c581fbbf41/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Homology Modelling and Molecular Dynamics Simulation of a ClC-5 `Gating' Mutation - Linus Conrad (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Unravelling the inhibitory mechanism of alpha-1 antitrypsin using accelerated molecular dynamics - Dr Ole Juul Andersen (University of Oxfor d) DTSTART;VALUE=DATE-TIME:20160901T140000 DTEND;VALUE=DATE-TIME:20160901T150000 UID:https://talks.ox.ac.uk/talks/id/d2eeeeb4-78f9-4691-86b0-f7ab84d9e1a7/ DESCRIPTION:\nSpeakers:\nDr Ole Juul Andersen (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d2eeeeb4-78f9-4691-86b0-f7ab84d9e1a7/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Unravelling the inhibitory mechanism of alpha-1 antitryps in using accelerated molecular dynamics - Dr Ole Juul Andersen (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Physical chemistry in biological membranes: resolving the chemical details of cell signaling - Dr Adam W Smith (University of Akron\, Ohio\, USA) DTSTART;VALUE=DATE-TIME:20160726T140000 DTEND;VALUE=DATE-TIME:20160726T150000 UID:https://talks.ox.ac.uk/talks/id/42ada761-20a6-4b19-8dbd-40cb739bf11e/ DESCRIPTION:The chemical interactions that drive biological function opera te in a complex environment. This is especially true of the plasma membran e\, where cells present an array of chemical receptors that transmit envir onmental cues inside the cell. The spatial and temporal arrangement of the se receptors from the nanometer to micrometer length scale is critical to function\, but the chemical forces driving this organization are not well understood. Membrane protein dimerization\, for example\, is a key regulat or of many receptor pathways\, but its role in others is still controversi al or completely unknown. Assembly of receptor complexes upon ligand stimu lation is central to many signaling pathways\, but the activation mechanis ms are still poorly understood. Finally\, lipid-protein interactions play many structural and regulatory roles in receptor activation\, but they are difficult to study in functioning membranes. I will describe two recent p rojects in my group. In one project we investigate membrane protein intera ctions in live cells using PIE-FCCS and related methods. These efforts hav e led to several key insights into the organization and activation mechani sm of receptors like plexins\, growth factor receptors\, and visual photor eceptors. The second project is to resolve the details of lipid-protein co upling in model membranes to build a more complete picture of the chemical landscape that governs cell communication.\nSpeakers:\nDr Adam W Smith (U niversity of Akron\, Ohio\, USA) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/42ada761-20a6-4b19-8dbd-40cb739bf11e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Physical chemistry in biological membranes: resolving the chemical details of cell signaling - Dr Adam W Smith (University of Akron \, Ohio\, USA) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Anomalous fluctuating diffusivity of a peripheral membrane protein on a lipid membrane surface - Dr Eiji Yamamoto (Keio University) DTSTART;VALUE=DATE-TIME:20160721T140000 DTEND;VALUE=DATE-TIME:20160721T150000 UID:https://talks.ox.ac.uk/talks/id/480ca98d-3156-4a1d-9fcb-98517bd37a80/ DESCRIPTION:\nSpeakers:\nDr Eiji Yamamoto (Keio University) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/480ca98d-3156-4a1d-9fcb-98517bd37a80/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Anomalous fluctuating diffusivity of a peripheral membran e protein on a lipid membrane surface - Dr Eiji Yamamoto (Keio University) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Interactions of membrane proteins with lipids: Insights from multi -scale molecular dynamics simulations - Dr Antreas Kalli (University of Ox ford) DTSTART;VALUE=DATE-TIME:20160728T140000 DTEND;VALUE=DATE-TIME:20160728T150000 UID:https://talks.ox.ac.uk/talks/id/264126a9-0b5c-4589-8b35-da9cc0bc248b/ DESCRIPTION:\nSpeakers:\nDr Antreas Kalli (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/264126a9-0b5c-4589-8b35-da9cc0bc248b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Interactions of membrane proteins with lipids: Insights f rom multi-scale molecular dynamics simulations - Dr Antreas Kalli (Univers ity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Ligand hydration and binding conformations - Akshay Sridhar (Unive rsity of Oxford) DTSTART;VALUE=DATE-TIME:20160714T140000 DTEND;VALUE=DATE-TIME:20160714T150000 UID:https://talks.ox.ac.uk/talks/id/a254ae87-de40-44de-be8f-9ac6759c2f28/ DESCRIPTION:\nSpeakers:\nAkshay Sridhar (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/a254ae87-de40-44de-be8f-9ac6759c2f28/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Ligand hydration and binding conformations - Akshay Sridh ar (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Back to breaking SAS-6 dimerisation and loopy interactions - work in progress - Julia Busch (University of Oxford) DTSTART;VALUE=DATE-TIME:20160707T140000 DTEND;VALUE=DATE-TIME:20160707T150000 UID:https://talks.ox.ac.uk/talks/id/cb793244-e699-4ae9-9770-5aeb49b4eead/ DESCRIPTION:\nSpeakers:\nJulia Busch (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/cb793244-e699-4ae9-9770-5aeb49b4eead/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Back to breaking SAS-6 dimerisation and loopy interaction s - work in progress - Julia Busch (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:SBCB seminar - Qinrui Wang (University of Oxford)\, Susan Leung (U niversity of Oxford) DTSTART;VALUE=DATE-TIME:20160630T140000 DTEND;VALUE=DATE-TIME:20160630T150000 UID:https://talks.ox.ac.uk/talks/id/f220b3ba-5d2c-423a-9e5b-23ef0b1e1136/ DESCRIPTION:\nSpeakers:\nQinrui Wang (University of Oxford)\, Susan Leung (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/f220b3ba-5d2c-423a-9e5b-23ef0b1e1136/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:SBCB seminar - Qinrui Wang (University of Oxford)\, Susan Leung (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20150528T140000 DTEND;VALUE=DATE-TIME:20150528T150000 UID:https://talks.ox.ac.uk/talks/id/9fd2f9d6-e677-4a9f-83d8-463e35737ff9/ DESCRIPTION:\nSpeakers:\nDr. Antreas Kalli (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9fd2f9d6-e677-4a9f-83d8-463e35737ff9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Potassium channel structure-function and dynamics: tales from comp utational necromancy. - Dr Prafulla Aryal (University of Oxford) DTSTART;VALUE=DATE-TIME:20160317T140000Z DTEND;VALUE=DATE-TIME:20160317T150000Z UID:https://talks.ox.ac.uk/talks/id/1321c95b-79d5-4e7c-909e-152c4180d718/ DESCRIPTION:\nSpeakers:\nDr Prafulla Aryal (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/1321c95b-79d5-4e7c-909e-152c4180d718/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Potassium channel structure-function and dynamics: tales from computational necromancy. - Dr Prafulla Aryal (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Membrane Simulations: from nanopores to viruses with several stops en route - Professor Mark Sansom (Department of Biochemistry) DTSTART;VALUE=DATE-TIME:20151015T140000 DTEND;VALUE=DATE-TIME:20151015T150000 UID:https://talks.ox.ac.uk/talks/id/7341669c-a0f0-409d-80b9-a083d08536d5/ DESCRIPTION:\nSpeakers:\nProfessor Mark Sansom (Department of Biochemistry ) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7341669c-a0f0-409d-80b9-a083d08536d5/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Membrane Simulations: from nanopores to viruses with seve ral stops en route - Professor Mark Sansom (Department of Biochemistry) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:From eukaryotic receptors to bacterial porins: modeling complex me mbrane systems - Dr Matthieu Chavent (University of Oxford) DTSTART;VALUE=DATE-TIME:20160121T140000Z DTEND;VALUE=DATE-TIME:20160121T150000Z UID:https://talks.ox.ac.uk/talks/id/9cdf1945-9d0e-4de8-8367-6b85299cc686/ DESCRIPTION:\nSpeakers:\nDr Matthieu Chavent (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9cdf1945-9d0e-4de8-8367-6b85299cc686/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:From eukaryotic receptors to bacterial porins: modeling c omplex membrane systems - Dr Matthieu Chavent (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The intrinsically disordered Plasmodium falciparum proteins PfEMP1 and KAHRP interactions with host erythrocyte spectrin - Erin Cutts (Unive rsity of Oxford) DTSTART;VALUE=DATE-TIME:20160128T153000Z DTEND;VALUE=DATE-TIME:20160128T163000Z UID:https://talks.ox.ac.uk/talks/id/872c4f51-a093-4794-ada1-d0080f3d63c0/ DESCRIPTION:\nSpeakers:\nErin Cutts (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/872c4f51-a093-4794-ada1-d0080f3d63c0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The intrinsically disordered Plasmodium falciparum protei ns PfEMP1 and KAHRP interactions with host erythrocyte spectrin - Erin Cut ts (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY: Predicting ligand selectivity and water stability with free energ y calculations - Matteo Aldeghi (University of Oxford) DTSTART;VALUE=DATE-TIME:20160204T153000Z DTEND;VALUE=DATE-TIME:20160204T163000Z UID:https://talks.ox.ac.uk/talks/id/232f6261-fd7e-487e-86ea-f8785aa2d893/ DESCRIPTION:\nSpeakers:\nMatteo Aldeghi (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/232f6261-fd7e-487e-86ea-f8785aa2d893/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk: Predicting ligand selectivity and water stability with f ree energy calculations - Matteo Aldeghi (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Characterising lipid-protein interactions through computational mo delling - George Hedger (University of Oxford) DTSTART;VALUE=DATE-TIME:20151210T140000Z DTEND;VALUE=DATE-TIME:20151210T150000Z UID:https://talks.ox.ac.uk/talks/id/ca179b36-8152-474f-882c-10ea2e2315ce/ DESCRIPTION:\nSpeakers:\nGeorge Hedger (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ca179b36-8152-474f-882c-10ea2e2315ce/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Characterising lipid-protein interactions through computa tional modelling - George Hedger (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Fitting and Assessment of Atomic Models in 3D Electron Microscopy Maps of Macromolecular Assemblies - Dr Maya Topf (TBA) DTSTART;VALUE=DATE-TIME:20150312T140000Z DTEND;VALUE=DATE-TIME:20150312T150000Z UID:https://talks.ox.ac.uk/talks/id/9c90c6af-6504-41ed-a7ca-ff42eb14773d/ DESCRIPTION:\nSpeakers:\nDr Maya Topf (TBA) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9c90c6af-6504-41ed-a7ca-ff42eb14773d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Fitting and Assessment of Atomic Models in 3D Electron Mi croscopy Maps of Macromolecular Assemblies - Dr Maya Topf (TBA) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational Studies of Bacterial Membrane Proteins - Dr Phillip Stansfeld (University of Oxford) DTSTART;VALUE=DATE-TIME:20151105T140000Z DTEND;VALUE=DATE-TIME:20151105T150000Z UID:https://talks.ox.ac.uk/talks/id/ffd5fe12-fece-410f-b55c-8d1e5e6278c8/ DESCRIPTION:\nSpeakers:\nDr Phillip Stansfeld (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ffd5fe12-fece-410f-b55c-8d1e5e6278c8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational Studies of Bacterial Membrane Proteins - Dr Phillip Stansfeld (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Computational Biochemistry for Drug Design - Assoc Prof Phil Biggi n (University of Oxford) DTSTART;VALUE=DATE-TIME:20151022T140000 DTEND;VALUE=DATE-TIME:20151022T150000 UID:https://talks.ox.ac.uk/talks/id/2ca7e0a3-3dab-41f8-ac2a-503b772963af/ DESCRIPTION:\nSpeakers:\nAssoc Prof Phil Biggin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2ca7e0a3-3dab-41f8-ac2a-503b772963af/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Computational Biochemistry for Drug Design - Assoc Prof P hil Biggin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Do proteins and cholesterol alter the stiffness of membranes? - Dr Philip Fowler (University of Oxford) DTSTART;VALUE=DATE-TIME:20151112T140000Z DTEND;VALUE=DATE-TIME:20151112T150000Z UID:https://talks.ox.ac.uk/talks/id/31e160ed-9bc4-4f26-9b80-2eca88dccc75/ DESCRIPTION:\nSpeakers:\nDr Philip Fowler (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/31e160ed-9bc4-4f26-9b80-2eca88dccc75/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Do proteins and cholesterol alter the stiffness of membra nes? - Dr Philip Fowler (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Elucidating a Potential Mechanism for the Dok7/MuSK/Membrane Compl ex - Amanda Buyan (University of Oxford) DTSTART;VALUE=DATE-TIME:20151119T140000Z DTEND;VALUE=DATE-TIME:20151119T150000Z UID:https://talks.ox.ac.uk/talks/id/423d87cf-8768-44a7-adee-1d8b90af67e2/ DESCRIPTION:\nSpeakers:\nAmanda Buyan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/423d87cf-8768-44a7-adee-1d8b90af67e2/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Elucidating a Potential Mechanism for the Dok7/MuSK/Membr ane Complex - Amanda Buyan (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Interaction of the human Band 3 anion exchanger protein with lipid s: Insights from molecular dynamics simulations - Dr Antreas Kalli (Univer sity of Oxford) DTSTART;VALUE=DATE-TIME:20151126T140000Z DTEND;VALUE=DATE-TIME:20151126T150000Z UID:https://talks.ox.ac.uk/talks/id/79b99912-8d2d-4d3a-929a-5808e32d06d3/ DESCRIPTION:\nSpeakers:\nDr Antreas Kalli (University of Oxford) LOCATION:Le Gros Clark Building (Lecture Theatre)\, off South Parks Road O X1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/79b99912-8d2d-4d3a-929a-5808e32d06d3/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Interaction of the human Band 3 anion exchanger protein w ith lipids: Insights from molecular dynamics simulations - Dr Antreas Kall i (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Simulating biological membranes and leaving academia - Dr Jean Hel ie (University of Oxford) DTSTART;VALUE=DATE-TIME:20151203T140000Z DTEND;VALUE=DATE-TIME:20151203T150000Z UID:https://talks.ox.ac.uk/talks/id/bab367d7-9058-4788-9bb5-619c2055561b/ DESCRIPTION:\nSpeakers:\nDr Jean Helie (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/bab367d7-9058-4788-9bb5-619c2055561b/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Simulating biological membranes and leaving academia - Dr Jean Helie (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular Dynamics Simulations of the TREK-2 Channel in a Lipid Bi layer - Viwan Jarerattanachat (University of Oxford) DTSTART;VALUE=DATE-TIME:20150806T140000 DTEND;VALUE=DATE-TIME:20150806T150000 UID:https://talks.ox.ac.uk/talks/id/c858232e-1b6c-4b6d-b233-bd9dc3f1b75e/ DESCRIPTION:\nSpeakers:\nViwan Jarerattanachat (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c858232e-1b6c-4b6d-b233-bd9dc3f1b75e/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular Dynamics Simulations of the TREK-2 Channel in a Lipid Bilayer - Viwan Jarerattanachat (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Rational GPCR Drug Design? - Dr Zara Sands (UCB BioPharma) DTSTART;VALUE=DATE-TIME:20150911T103000 DTEND;VALUE=DATE-TIME:20150911T113000 UID:https://talks.ox.ac.uk/talks/id/bbddbdc8-538c-4b75-ae38-bd9fb22603fb/ DESCRIPTION:\nSpeakers:\nDr Zara Sands (UCB BioPharma) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/bbddbdc8-538c-4b75-ae38-bd9fb22603fb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Rational GPCR Drug Design? - Dr Zara Sands (UCB BioPharma ) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Disgreement in structural evidence for glutamate receptor desensit isation motions? - Dr Maria Musgaard (University of Oxford) DTSTART;VALUE=DATE-TIME:20151001T140000 DTEND;VALUE=DATE-TIME:20151001T150000 UID:https://talks.ox.ac.uk/talks/id/faa25878-7e94-468f-a67d-59e7ed05fcfc/ DESCRIPTION:\nSpeakers:\nDr Maria Musgaard (University of Oxford) LOCATION:Le Gros Clark Building (Lecture Theatre)\, off South Parks Road O X1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/faa25878-7e94-468f-a67d-59e7ed05fcfc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Disgreement in structural evidence for glutamate receptor desensitisation motions? - Dr Maria Musgaard (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular dynamics studies of lipase-surface interactions - Natali e Willems (University of Oxford) DTSTART;VALUE=DATE-TIME:20151008T140000 DTEND;VALUE=DATE-TIME:20151008T150000 UID:https://talks.ox.ac.uk/talks/id/300a9477-ac3a-4c7f-8072-1e6cd88a11ac/ DESCRIPTION:\nSpeakers:\nNatalie Willems (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/300a9477-ac3a-4c7f-8072-1e6cd88a11ac/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular dynamics studies of lipase-surface interactions - Natalie Willems (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Proton Oligopeptide Transporters: Insights from Computer Modelling - Firdaus Samsudin (University of Oxford) DTSTART;VALUE=DATE-TIME:20150402T140000 DTEND;VALUE=DATE-TIME:20150402T150000 UID:https://talks.ox.ac.uk/talks/id/5f6d6ee8-f9e1-4641-83d0-7d6d34aba858/ DESCRIPTION:\nSpeakers:\nFirdaus Samsudin (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/5f6d6ee8-f9e1-4641-83d0-7d6d34aba858/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Proton Oligopeptide Transporters: Insights from Computer Modelling - Firdaus Samsudin (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Title TBC DTSTART;VALUE=DATE-TIME:20150305T140000Z DTEND;VALUE=DATE-TIME:20150305T150000Z UID:https://talks.ox.ac.uk/talks/id/603f61d9-9688-4869-adfb-fd4e8120cc3c/ DESCRIPTION:\nSpeakers:\nBen Morris (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/603f61d9-9688-4869-adfb-fd4e8120cc3c/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Title TBC TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Characterising Lipid-Protein Interactions through Computational Mo delling - George Hedger (University of Oxford) DTSTART;VALUE=DATE-TIME:20150326T140000Z DTEND;VALUE=DATE-TIME:20150326T150000Z UID:https://talks.ox.ac.uk/talks/id/385f94a5-58d1-4141-b00e-6e95d07a366d/ DESCRIPTION:\nSpeakers:\nGeorge Hedger (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/385f94a5-58d1-4141-b00e-6e95d07a366d/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Characterising Lipid-Protein Interactions through Computa tional Modelling - George Hedger (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Interaction of peripheral proteins with phosphatidylinositol lipid s - Fiona Naughton (University of Oxford) DTSTART;VALUE=DATE-TIME:20150716T140000 DTEND;VALUE=DATE-TIME:20150716T150000 UID:https://talks.ox.ac.uk/talks/id/2508c30b-fc89-476f-9b40-2f19fb656419/ DESCRIPTION:\nSpeakers:\nFiona Naughton (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2508c30b-fc89-476f-9b40-2f19fb656419/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Interaction of peripheral proteins with phosphatidylinosi tol lipids - Fiona Naughton (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The porous nature of DNA-origami nanotubes revealed by atomistic s imulations - Vishal Maingi DTSTART;VALUE=DATE-TIME:20150618T140000 DTEND;VALUE=DATE-TIME:20150618T150000 UID:https://talks.ox.ac.uk/talks/id/7256b5d5-55f7-4365-b4a2-4589f29bc52a/ DESCRIPTION:\nSpeakers:\nVishal Maingi LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/7256b5d5-55f7-4365-b4a2-4589f29bc52a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The porous nature of DNA-origami nanotubes revealed by at omistic simulations - Vishal Maingi TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Studying the architecture of the Fibroblast Growth Factor Receptor signalling complex - Santiago Manrique Zuniga DTSTART;VALUE=DATE-TIME:20150625T140000 DTEND;VALUE=DATE-TIME:20150625T150000 UID:https://talks.ox.ac.uk/talks/id/71e3da9a-6054-4c12-a868-72639113e4b6/ DESCRIPTION:\nSpeakers:\nSantiago Manrique Zuniga LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/71e3da9a-6054-4c12-a868-72639113e4b6/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Studying the architecture of the Fibroblast Growth Factor Receptor signalling complex - Santiago Manrique Zuniga TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:The fragment molecular orbital method for quantum-mechanical calcu lations of proteins and other large molecular systems - Dr Dmitri Federov (NRI\, National Institute of Advanced Industrial Science and Technology (A IST)\, Japan) DTSTART;VALUE=DATE-TIME:20150724T140000 DTEND;VALUE=DATE-TIME:20150724T150000 UID:https://talks.ox.ac.uk/talks/id/c704d1ae-3cd3-4c80-b016-7d6b50f71893/ DESCRIPTION:\nSpeakers:\nDr Dmitri Federov (NRI\, National Institute of Ad vanced Industrial Science and Technology (AIST)\, Japan) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/c704d1ae-3cd3-4c80-b016-7d6b50f71893/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:The fragment molecular orbital method for quantum-mechani cal calculations of proteins and other large molecular systems - Dr Dmitri Federov (NRI\, National Institute of Advanced Industrial Science and Tech nology (AIST)\, Japan) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Dynamic Pharmacophore Models from Coarse Grain MD Simulations - Ni cholas Michelarakis (University of Oxford) DTSTART;VALUE=DATE-TIME:20150730T140000 DTEND;VALUE=DATE-TIME:20150730T150000 UID:https://talks.ox.ac.uk/talks/id/ef6593a1-18c4-4b61-8903-468c81c53017/ DESCRIPTION:\nSpeakers:\nNicholas Michelarakis (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/ef6593a1-18c4-4b61-8903-468c81c53017/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Dynamic Pharmacophore Models from Coarse Grain MD Simulat ions - Nicholas Michelarakis (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Ligand Hydration and their Role in Binding Conformation - Akshay Sridhar (University of Oxford) DTSTART;VALUE=DATE-TIME:20150813T140000 DTEND;VALUE=DATE-TIME:20150813T150000 UID:https://talks.ox.ac.uk/talks/id/12c726ef-7d27-491d-bbb1-24dfc2de88d6/ DESCRIPTION:\nSpeakers:\nAkshay Sridhar (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/12c726ef-7d27-491d-bbb1-24dfc2de88d6/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Ligand Hydration and their Role in Binding Conformation - Akshay Sridhar (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Veni\, Vidi\, Voronoi: Attacking Viruses with Spherical Voronoi Di agrams - Dr Tyler Reddy (University of Oxford) DTSTART;VALUE=DATE-TIME:20150903T140000 DTEND;VALUE=DATE-TIME:20150903T150000 UID:https://talks.ox.ac.uk/talks/id/08235bcf-ee34-4d6a-866b-3817376d3ecc/ DESCRIPTION:\nSpeakers:\nDr Tyler Reddy (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/08235bcf-ee34-4d6a-866b-3817376d3ecc/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Veni\, Vidi\, Voronoi: Attacking Viruses with Spherical V oronoi Diagrams - Dr Tyler Reddy (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:High Throughput Simulation and Analysis of Intrinsic Membrane Prot eins - Tom Newport (University of Oxford) DTSTART;VALUE=DATE-TIME:20150820T140000 DTEND;VALUE=DATE-TIME:20150820T150000 UID:https://talks.ox.ac.uk/talks/id/d2513c62-4e36-4ca3-b39d-0d11c630503f/ DESCRIPTION:\nSpeakers:\nTom Newport (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/d2513c62-4e36-4ca3-b39d-0d11c630503f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:High Throughput Simulation and Analysis of Intrinsic Memb rane Proteins - Tom Newport (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Biasing of the Human delta-type Opioid Receptor\, Ligand Binding i n a Heteromeric GABA-A Receptor - Helen Langley (UCL)\, Naushad Velgy (Uni versity of Oxford) DTSTART;VALUE=DATE-TIME:20150917T140000 DTEND;VALUE=DATE-TIME:20150917T150000 UID:https://talks.ox.ac.uk/talks/id/97b7da2c-a3fa-4967-9c79-0e9ecc25b084/ DESCRIPTION:\nSpeakers:\nHelen Langley (UCL)\, Naushad Velgy (University o f Oxford) LOCATION:Le Gros Clark Building (Lecture Theatre)\, off South Parks Road O X1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/97b7da2c-a3fa-4967-9c79-0e9ecc25b084/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Biasing of the Human delta-type Opioid Receptor\, Ligand Binding in a Heteromeric GABA-A Receptor - Helen Langley (UCL)\, Naushad V elgy (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Molecular Dynamics Simulations of type A GABA receptors\; Bacteria l membrane lipoprotein modifications and transfer: A molecular dynamics ta le of the (lipid) tails - Shanlin Rao (University of Oxford)\, Chrissie Yo on (University of Oxford) DTSTART;VALUE=DATE-TIME:20160211T153000Z DTEND;VALUE=DATE-TIME:20160211T163000Z UID:https://talks.ox.ac.uk/talks/id/46dedf1d-426a-4b08-bd2b-e1dd18578d9f/ DESCRIPTION:\nSpeakers:\nShanlin Rao (University of Oxford)\, Chrissie Yoo n (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/46dedf1d-426a-4b08-bd2b-e1dd18578d9f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Molecular Dynamics Simulations of type A GABA receptors\; Bacterial membrane lipoprotein modifications and transfer: A molecular dy namics tale of the (lipid) tails - Shanlin Rao (University of Oxford)\, Ch rissie Yoon (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY: Protein druggability: the JEDI approach - Dr Remi Cuchillo (Univ ersity of Oxford) DTSTART;VALUE=DATE-TIME:20150924T140000 DTEND;VALUE=DATE-TIME:20150924T150000 UID:https://talks.ox.ac.uk/talks/id/941cc7d7-3554-4d14-8f1e-977d474b9a4a/ DESCRIPTION:\nSpeakers:\nDr Remi Cuchillo (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Meeting Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/941cc7d7-3554-4d14-8f1e-977d474b9a4a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk: Protein druggability: the JEDI approach - Dr Remi Cuchi llo (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Protein clustering and lipid complexity: using molecular dynamics simulations to study biological membranes - Dr Anna Duncan (University of Oxford) DTSTART;VALUE=DATE-TIME:20160407T140000 DTEND;VALUE=DATE-TIME:20160407T150000 UID:https://talks.ox.ac.uk/talks/id/8d34a399-f4f8-4077-8df0-270f53917fc8/ DESCRIPTION:\nSpeakers:\nDr Anna Duncan (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8d34a399-f4f8-4077-8df0-270f53917fc8/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Protein clustering and lipid complexity: using molecular dynamics simulations to study biological membranes - Dr Anna Duncan (Unive rsity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Targeting the Hedgehog Pathway in disease: a structural biology ap proach - Lea Sefer (University of Oxford) DTSTART;VALUE=DATE-TIME:20160421T140000 DTEND;VALUE=DATE-TIME:20160421T150000 UID:https://talks.ox.ac.uk/talks/id/0d586198-5f55-495e-850f-e853927c84b9/ DESCRIPTION:\nSpeakers:\nLea Sefer (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/0d586198-5f55-495e-850f-e853927c84b9/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Targeting the Hedgehog Pathway in disease: a structural b iology approach - Lea Sefer (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Direct comparison of lipid bilayer structures between simulations and experiments - Dr Samuli Ollila (Aalto University\, Finland) DTSTART;VALUE=DATE-TIME:20160414T140000 DTEND;VALUE=DATE-TIME:20160414T150000 UID:https://talks.ox.ac.uk/talks/id/edc03afc-6471-4ecc-995f-10cb4d076dbb/ DESCRIPTION:\nSpeakers:\nDr Samuli Ollila (Aalto University\, Finland) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/edc03afc-6471-4ecc-995f-10cb4d076dbb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Direct comparison of lipid bilayer structures between sim ulations and experiments - Dr Samuli Ollila (Aalto University\, Finland) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Through the atomistic looking glass: Interactions between proteins and other macromolecules - Laura Domicevica (University of Oxford) DTSTART;VALUE=DATE-TIME:20160519T140000 DTEND;VALUE=DATE-TIME:20160519T150000 UID:https://talks.ox.ac.uk/talks/id/080df774-db45-4b9d-ad8b-0b5306e3fbcb/ DESCRIPTION:\nSpeakers:\nLaura Domicevica (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/080df774-db45-4b9d-ad8b-0b5306e3fbcb/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Through the atomistic looking glass: Interactions between proteins and other macromolecules - Laura Domicevica (University of Oxfor d) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:DNA nanotube-membrane interactions at coarse-grain and atomic reso lutions: a molecular dynamics simulation tour - Vishal Maingi (University of Oxford) DTSTART;VALUE=DATE-TIME:20160505T140000 DTEND;VALUE=DATE-TIME:20160505T150000 UID:https://talks.ox.ac.uk/talks/id/3f3ba4c6-8742-4e38-95bc-8269c978a12f/ DESCRIPTION:\nSpeakers:\nVishal Maingi (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/3f3ba4c6-8742-4e38-95bc-8269c978a12f/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:DNA nanotube-membrane interactions at coarse-grain and at omic resolutions: a molecular dynamics simulation tour - Vishal Maingi (Un iversity of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:From Biological Self-Assembly to Novel Peptide Nanostructures with Unique Mechanical\, Optical\, Piezoelectric and Semiconductive Properties - Prof. Ehud Gazit (Tel Aviv University\, Israel) DTSTART;VALUE=DATE-TIME:20160512T140000 DTEND;VALUE=DATE-TIME:20160512T150000 UID:https://talks.ox.ac.uk/talks/id/2c5fd8a3-3b98-4576-b4d2-a9c42209c960/ DESCRIPTION:\nSpeakers:\nProf. Ehud Gazit (Tel Aviv University\, Israel) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2c5fd8a3-3b98-4576-b4d2-a9c42209c960/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:From Biological Self-Assembly to Novel Peptide Nanostruct ures with Unique Mechanical\, Optical\, Piezoelectric and Semiconductive P roperties - Prof. Ehud Gazit (Tel Aviv University\, Israel) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:PH\, PIPs and parasols: Investigating peripheral protein-membrane interactions using Umbrella Sampling - Fiona Naughton (University of Oxfor d) DTSTART;VALUE=DATE-TIME:20160527T130000 DTEND;VALUE=DATE-TIME:20160527T140000 UID:https://talks.ox.ac.uk/talks/id/8046e38f-d438-4e5c-80e0-09f193d47ba4/ DESCRIPTION:\nSpeakers:\nFiona Naughton (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/8046e38f-d438-4e5c-80e0-09f193d47ba4/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:PH\, PIPs and parasols: Investigating peripheral protein- membrane interactions using Umbrella Sampling - Fiona Naughton (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Toward dynamic pharmacophore models by coarse-grained molecular dy namics simulations - Nicholas Michelarakis (University of Oxford) DTSTART;VALUE=DATE-TIME:20160602T140000 DTEND;VALUE=DATE-TIME:20160602T150000 UID:https://talks.ox.ac.uk/talks/id/2669eaf9-8948-4200-84d0-51bfa4b2520a/ DESCRIPTION:\nSpeakers:\nNicholas Michelarakis (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/2669eaf9-8948-4200-84d0-51bfa4b2520a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Toward dynamic pharmacophore models by coarse-grained mol ecular dynamics simulations - Nicholas Michelarakis (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:TREK-2 in lipid bilayers : the multiscale-simulation insight - Viw an Jarerattanachat (University of Oxford) DTSTART;VALUE=DATE-TIME:20160609T140000 DTEND;VALUE=DATE-TIME:20160609T150000 UID:https://talks.ox.ac.uk/talks/id/478de7ca-a0de-4b06-bd69-d390f579b229/ DESCRIPTION:\nSpeakers:\nViwan Jarerattanachat (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/478de7ca-a0de-4b06-bd69-d390f579b229/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:TREK-2 in lipid bilayers : the multiscale-simulation insi ght - Viwan Jarerattanachat (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Bringing membrane proteins to life with MemProtMD - Tom Newport (U niversity of Oxford) DTSTART;VALUE=DATE-TIME:20160616T140000 DTEND;VALUE=DATE-TIME:20160616T150000 UID:https://talks.ox.ac.uk/talks/id/9495035f-d63c-4cc6-bec2-c489dec54a1a/ DESCRIPTION:\nSpeakers:\nTom Newport (University of Oxford) LOCATION:Le Gros Clark Building (Anatomy Lecture Theatre)\, off South Park s Road OX1 3QX TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/9495035f-d63c-4cc6-bec2-c489dec54a1a/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Bringing membrane proteins to life with MemProtMD - Tom N ewport (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT BEGIN:VEVENT SUMMARY:Sampling challenges in membrane protein-lipid and protein-protein binding - Jan Domanski (University of Oxford) DTSTART;VALUE=DATE-TIME:20160623T140000 DTEND;VALUE=DATE-TIME:20160623T150000 UID:https://talks.ox.ac.uk/talks/id/0967d17a-e97a-4ca7-a4a9-ad13508686d0/ DESCRIPTION:\nSpeakers:\nJan Domanski (University of Oxford) LOCATION:Dorothy Crowfoot Hodgkin Building (Main Seminar Room)\, off South Parks Road OX1 3QU TZID:Europe/London URL:https://talks.ox.ac.uk/talks/id/0967d17a-e97a-4ca7-a4a9-ad13508686d0/ BEGIN:VALARM ACTION:display DESCRIPTION:Talk:Sampling challenges in membrane protein-lipid and protein -protein binding - Jan Domanski (University of Oxford) TRIGGER:-PT1H END:VALARM END:VEVENT END:VCALENDAR