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SUMMARY:Regulation of RyR2 in the heart and brain - Professor Peter Jones 
 (University of Otago)
DTSTART;VALUE=DATE-TIME:20250707T110000
DTEND;VALUE=DATE-TIME:20250707T120000
UID:https://talks.ox.ac.uk/talks/id/1d55d369-5e7f-4bbf-aa08-bc2052082f13/
DESCRIPTION:Type-2 ryanodine receptor (RyR2) mediated calcium release cont
 rols the contraction of cardiac myocytes and the excitability of neurons. 
 Consequently\, inappropriate activation of RyR2 leads to disease\, such as
  arrhythmias and Alzheimer's disease. Prof Jones will describe his publish
 ed and unpublished research examining the pathophysiological regulation of
  RyR2 in the heart and brain. This spans from single protein super-resolut
 ion microscopy\, through real time calcium imaging\, to in vivo analysis i
 n animal models\, and characterisation in human tissue. He will also prese
 nt data on how targeting RyR2 might offer new treatments for arrhythmias a
 nd Alzheimer’s disease. \n\nSPEAKER BIOGRAPHY\n\nPete Jones is a Profess
 or in the Department of Physiology at the University of Otago (NZ) and co-
 director of the University of Otago HeartOtago Research Theme. He obtained
  his PhD from the University of Leeds (UK) in 2004 and then went on to pos
 tdoctoral training in Calgary (Canada). He took up his current position in
  2010. His principal research focuses on intracellular calcium in cardiac 
 myocytes and neurons. His research is funded by the Health Research Counci
 l of New Zealand\, Royal Society Marsden fund\, the Heart Foundation of NZ
  and New Zealand Neurological Foundation.\nSpeakers:\nProfessor Peter Jone
 s (University of Otago)
LOCATION:Sherrington Library (Sherrington Building)\, off Parks Road OX1 3
 PT
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/1d55d369-5e7f-4bbf-aa08-bc2052082f13/
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DESCRIPTION:Talk:Regulation of RyR2 in the heart and brain - Professor Pet
 er Jones (University of Otago)
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