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SUMMARY:Programming and reprogramming brain cancer stem cells - Dr Steve P
 ollard (Edinburgh University)
DTSTART;VALUE=DATE-TIME:20170117T100000Z
DTEND;VALUE=DATE-TIME:20170117T110000Z
UID:https://talks.ox.ac.uk/talks/id/1ec5c05c-9fe0-4667-b2ea-1b18f5f2c051/
DESCRIPTION:Neural stem cells produce the neurons and glial cells that mak
 e up our nervous system. They can be expanded continuously in the laborato
 ry\, thereby providing an unlimited source of human cells for disease mode
 lling and regenerative medicine.\nCells that have molecular hallmarks of n
 eural stem cells drive human brain cancers\, such as glioblastoma. A full 
 understanding of the molecular and cellular events that control neural ste
 m cell fate may therefore reveal new therapeutic strategies to treat this 
 devastating disease.\nWe are exploiting the latest experimental tools of m
 olecular and cellular biology to address the following questions: How do n
 eural stem cells make the decision to make more copies of themselves (self
 -renew)\, or become specialised (differentiate)? Why do brain tumour stem 
 cells display unconstrained self-renewal? Are those genes and pathways tha
 t initiate and maintain neural stem cell identity useful therapeutic targe
 ts for glioblastoma? Can we identify new drugs that can specifically block
  self-renewal of brain tumour stem cells?\n\nSpeakers:\nDr Steve Pollard (
 Edinburgh University)
LOCATION:NDM Building (Basement seminar room)\, Headington OX3 7FZ
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/1ec5c05c-9fe0-4667-b2ea-1b18f5f2c051/
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DESCRIPTION:Talk:Programming and reprogramming brain cancer stem cells - D
 r Steve Pollard (Edinburgh University)
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