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SUMMARY:Ebola virus: Outbreaks\, immunity\, persistence and spillover - Pr
 ofessor Miles Carroll (University of Oxford)
DTSTART;VALUE=DATE-TIME:20260309T133000Z
DTEND;VALUE=DATE-TIME:20260309T143000Z
UID:https://talks.ox.ac.uk/talks/id/32787722-ca54-4859-86b0-5e8d23abaa73/
DESCRIPTION:The 2013-2016 Ebola virus (EBOV) epidemic in West Africa furth
 er highlighted the need to understand the processes of zoonotic spillover 
 events of filoviruses and other high consequence emerging viruses. Further
 more\, the reports of subsequent outbreaks of Zaire and Bombali Ebola viru
 ses in addition to Marburg virus\, in the region\, suggests numerous known
  and unknown emerging viruses have been circulating in animal reservoirs b
 efore the initial spillover event of EBOV in 2013. The evidence of EBOV vi
 rus persistence in the testes of male survivors provides additional threat
 s of sexual transmission associated outbreaks. We have been studying EBOV 
 disease survivors and wildlife hunters in the forested region of Guinea si
 nce 2015. The forest\, which straddle the borders with Liberia and Sierra 
 Leonne\, has extensive biodiversity and is home to an array of bat species
  as well as other small mammals previously identified as reservoirs for em
 erging viruses. \n\nI will discuss our work on molecular and sero-epidemio
 logy that provided evidence of prior spillover of emerging viruses in the 
 region as well as long term virus persistence in male survivors and the pu
 blic health implications of future outbreaks from the “human reservoir
 ”. \n\nProfessor Miles Carroll is Professor of Emerging Viruses and lead
 s the High Consequence Emerging Viruses research group at the Pandemic Sci
 ences Institute\, University of Oxford. Previously Professor Carroll was H
 ead of Research at the National Infections Service at Public Health Englan
 d\, Porton Down from 2008–2022. His current research portfolio includes:
  naturally acquired immunity to EBOV and other high consequence pathogens\
 , understanding the host response to infection\, high consequence emerging
  disease vaccines and diagnostics\, and the application of molecular epide
 miology to outbreaks. He is also involved in ongoing infectious disease re
 search in West Africa which supports capacity building for the region. Pro
 fessor Carroll serves on a variety of Scientific Advisory Boards including
  the UK Animal and Plant Health Agency\, Defence Science and Technology La
 boratories\, UK Vaccines Network and the WHO R&D Road Map for Priority Pat
 hogens. He has been awarded numerous honorary awards in recognition of his
  research contributions to the field of infectious diseases. . https://www
 .chg.ox.ac.uk/people/miles-carroll \n\nSpeakers:\nProfessor Miles Carroll 
 (University of Oxford)
LOCATION:Seminar rooms 7 & 8 in the Life and Mind Building\, Lower Ground 
 Floor South Parks Road\, OX1 3EL
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/32787722-ca54-4859-86b0-5e8d23abaa73/
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DESCRIPTION:Talk:Ebola virus: Outbreaks\, immunity\, persistence and spill
 over - Professor Miles Carroll (University of Oxford)
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