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SUMMARY:From lizards to humans: early embryogenesis in the light of evolut
 ion - Dr Antonia Weberling (University of Oxford)
DTSTART;VALUE=DATE-TIME:20260217T130000Z
DTEND;VALUE=DATE-TIME:20260217T140000Z
UID:https://talks.ox.ac.uk/talks/id/45faf0bf-ed5f-40e3-95ae-d809c7d2de3f/
DESCRIPTION:Abstract: Pre-gastrulation embryogenesis\, encompassing the i
 nitial lineage segregations\, acquisition and consecutive loss of naïve p
 luripotency\, anterior-posterior patterning\, and the initiation of gastru
 lation via primitive streak formation\, has been studied in much detail in
  mouse\, human\, and non-human primate embryos. However\, our knowledge of
  the evolution of these processes across amniotes\, especially reptiles\, 
 remains limited. Commonly\, all reptiles are thought to follow chicken dev
 elopment\, which is characterised by a two-dimensional flat disc at peri-g
 astrulation stages while mammalian embryogenesis is characterised by highl
 y diverse 3-dimensional pre- and peri-gastrulation morphogenesis. These di
 fferential modes of embryogenesis may result in differential signalling re
 quirements for embryonic patterning. Showcasing two lizard species\, the b
 rown anole and the veiled chameleon\, I will describe pre-gastrulation dev
 elopment of non-avian reptiles revealing a massive variability of embryoni
 c modes within reptiles. The variability in morphogenesis is mirrored in d
 ifferential activation of signalling pathways exhibiting divergence in pre
 viously thought canonical patterning processes.\n\nBio: Dr Weberling (BSc 
 & MSc Biochemistry\, Freie Universität Berlin\, Germany) was awarded a Ph
 D Fellowship of the Marie Skłodowska-Curie Actions Horizon 2020 Internati
 onal Training Network ImageInLife to complete her PhD at the University of
  Cambridge\, UK\, focussing on mouse and human embryogenesis at peri- and 
 early post-implantation stages.\nFollowing her PhD\, Dr Weberling was awar
 ded a postdoctoral research fellowship at All Souls College\, Oxford\, to 
 build up her independent research. She focusses on understanding early emb
 ryogenesis of non- or emerging model organisms of the amniote phylum. Gain
 ing knowledge of  embryogenesis in the different families across the amni
 ote phylogenetic tree will enable to carry out cross-species comparative s
 tudies to understand the degree of conservation of key developmental proce
 sses. For this\, she established a global network of collaborators to acce
 ss representative species of different amniote families. Besides her resea
 rch\, Dr Weberling is a writer and an artist. Her paintings and fine print
 s have featured in a number of exhibitions in Germany and Canada and her p
 oetry has been published in numerous anthologies. Her first novel was publ
 ished in October 2025 in Germany.\nSpeakers:\nDr Antonia Weberling (Univer
 sity of Oxford)
LOCATION:This event is hybrid
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/45faf0bf-ed5f-40e3-95ae-d809c7d2de3f/
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DESCRIPTION:Talk:From lizards to humans: early embryogenesis in the light 
 of evolution - Dr Antonia Weberling (University of Oxford)
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