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SUMMARY:ADP-ribosylation signalling in regulation of genome stability - Dr
  Ivan Ahel (Sir William Dunn School of Pathology\, University of Oxford)
DTSTART;VALUE=DATE-TIME:20170227T130000Z
DTEND;VALUE=DATE-TIME:20170227T140000Z
UID:https://talks.ox.ac.uk/talks/id/a2993e70-8a66-49b0-9265-363a2ef62311/
DESCRIPTION:Dr Ahel's lab employs a combination of structural studies\, ce
 ll biology\, and animal models to study cellular responses to DNA damage. 
 In particular\, their area of focus is on regulation of proteins involved 
 in DNA repair and genome stability by ADP-ribosylation\, a post-translatio
 nal protein modification catalyzed by a family of enzymes called poly(ADP-
 ribose) polymerases (PARPs). PARPs have been linked to a number of cellula
 r pathways including DNA repair\, modulation of chromatin structure\, apop
 tosis\, and transcription\nSpeakers:\nDr Ivan Ahel (Sir William Dunn Schoo
 l of Pathology\, University of Oxford)
LOCATION:Dorothy Crowfoot Hodgkin Building (Main seminar room)\, off South
  Parks Road OX1 3QU
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/a2993e70-8a66-49b0-9265-363a2ef62311/
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DESCRIPTION:Talk:ADP-ribosylation signalling in regulation of genome stabi
 lity - Dr Ivan Ahel (Sir William Dunn School of Pathology\, University of 
 Oxford)
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