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SUMMARY:Modulating Hemoglobin Affinity to Optimize Oxygen Delivery: A New 
 Paradigm in Critical Care? - Ian Welsby (Duke University School of Medicin
 e)
DTSTART;VALUE=DATE-TIME:20240606T150000
DTEND;VALUE=DATE-TIME:20240606T160000
UID:https://talks.ox.ac.uk/talks/id/b677583a-c606-4acc-b409-4a1e2b8b8b37/
DESCRIPTION:SPEAKER BIOGRAPHY\n\nI practice in a busy cardiothoracic and t
 ransplant center in the OR and ICU and Chair the Transfusion Committee at 
 the affiliated Durham VA Hospital. My research is focused on my interest i
 n thrombosis\, bleeding\, transfusion and anticoagulation\, which is close
 ly related to an extended commitment to understanding perioperative coagul
 ation\, coagulopathy\, anticoagulation\, transfusion and associated advers
 e outcomes.\nIn terms of grant support\, as the Duke site PI for the Rare 
 Thrombotic Diseases Clinical Research Network (NIH U54 HL77878\; PI Dr T O
 rtel)\, patients were enrolled for this prospective\, observational cohort
  study that evaluated the anti-heparin/platelet factor 4 antibodies\, that
  commonly develop after cardiac surgery\, as an independent risk factor fo
 r early and late thromboembolic complications. \nAvoiding transfusion is d
 esirable but\, if necessary\, transfusing the optimal product is essential
 . I completed funding to study Point of Care RBC Washing to Prevent Transf
 usion-Related Pulmonary Complications (NIH R01HL121232-01\; Mayo Clinic an
 d overall PI Dr DJ Kor\, co-PIO/Duke PI Dr IJ Welsby) and have been the Du
 ke PI for RECIPI a BARDA funded multicenter study of pathogen reduced red 
 blood cells in cardiac surgery.\nOn-going interests include manipulating t
 he oxygen affinity of hemoglobin to optimize oxygen delivery and the use o
 f clotting factor concentrates to reverse perioperative coagulopathy.\nSpe
 akers:\nIan Welsby (Duke University School of Medicine)
LOCATION:Sherrington Library (Sherrington Building)\, off Parks Road OX1 3
 PT
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/b677583a-c606-4acc-b409-4a1e2b8b8b37/
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DESCRIPTION:Talk:Modulating Hemoglobin Affinity to Optimize Oxygen Deliver
 y: A New Paradigm in Critical Care? - Ian Welsby (Duke University School o
 f Medicine)
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