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SUMMARY:Cross-talk between cell mechanics\, cell shape and cell fate - Pro
 fessor Ewa Paluch (University of Cambridge)
DTSTART;VALUE=DATE-TIME:20250724T160000
DTEND;VALUE=DATE-TIME:20250724T170000
UID:https://talks.ox.ac.uk/talks/id/be31e478-1930-41f9-9f6f-86a3ab764450/
DESCRIPTION:A precise control of cell morphology is key for cell physiolog
 y\, and cell shape deregulation is at the heart of many pathological disor
 ders. Furthermore\, transitions in cellular fate and state are often assoc
 iated with changes in cell shape\, and strong evidence points to the exist
 ence of feedbacks between mechanics\, morphology and fate decisions. Cell 
 morphology is intrinsically controlled by mechanical forces acting on the 
 cell surface\, to understand shape it is thus essential to investigate the
  regulation of cellular mechanics. I will discuss how cellular mechanical 
 properties drive cellular shape changes\, and the cross-talk between mecha
 nics and state in cellular transitions.\n\nSPEAKER BIOGRAPHY\n\nEwa Paluch
  graduated in Physics from the Ecole Normale Supérieure in Lyon in 2001 a
 nd did a PhD in Biophysics at the Curie Institute in Paris between 2001 to
  2005. She started her research group in 2006 at the Max Planck Institute 
 of Molecular Cell Biology and Genetics in Dresden\, as a joint appointment
  with the International Institute of Molecular and Cell Biology in Warsaw.
  In 2013\, she was appointed Professor of Cell Biophysics at the MRC LMCB\
 , University College London. From 2014 to 2018\, she also headed the new U
 CL Institute for the Physics of Living Systems\, which promotes collaborat
 ions between physicists and biologists at UCL. In 2018 she was elected Cha
 ir of Anatomy at the University of Cambridge. Ewa is the 19th Professor of
  Anatomy at Cambridge\, and the first woman to hold this Chair in its 300-
 year history. She has received a number of awards\, including the Hooke Me
 dal from the British Society for Cell Biology in 2017\, EMBO membership in
  2018\, the Blavatnik Award for Young Scientists in the UK in 2019\, and t
 he DGZ Carl Zeiss Lecture Award in 2022. In 2024\, she was featured as one
  of “50 Scientists that inspire” for the 50th Anniversary of Cell Pres
 s.\n\nEwa leads a cross-disciplinary lab combining molecular and cell biol
 ogy\, biophysics\, quantitative imaging and modelling to investigate the f
 undamental principles underlying cellular morphogenesis. The lab’s resea
 rch directions span cell surface mechanics regulation\, the control of cel
 l shape during cell division and migration\, and the cross-talk between ce
 ll mechanics\, cell shape and cell fate during cellular transitions.\n\n\n
 Lab website:\nhttps://paluchlab.uk\n\n\nSpeakers:\nProfessor Ewa Paluch (U
 niversity of Cambridge)
LOCATION:Sherrington Library (Sherrington Building)\, off Parks Road OX1 3
 PT
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/be31e478-1930-41f9-9f6f-86a3ab764450/
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DESCRIPTION:Talk:Cross-talk between cell mechanics\, cell shape and cell f
 ate - Professor Ewa Paluch (University of Cambridge)
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