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SUMMARY:Engineering and Safeguarding Synthetic Genomes - Prof Patrick Cai 
 (University of Manchester)
DTSTART;VALUE=DATE-TIME:20260306T140000Z
DTEND;VALUE=DATE-TIME:20260306T150000Z
UID:https://talks.ox.ac.uk/talks/id/f5f91058-c9f0-4d81-b649-3de136b431af/
DESCRIPTION:Over the last 12 years\, my lab has been building synthetic ye
 ast chromosomes from scratch. These synthetic genomes are engineered to al
 low genome-wide directed evolution with a system call SCRaMbLE (Synthetic 
 Chromosome Recombination and Modification by LoxP-Mediated Evolution). SCR
 aMbLE allows the synthetic cells to process the information (e.g. environm
 ental stress) differently from their wildtype counterparts\, and also enab
 les them to re-configure the genomes to cope with the environments. I will
  present our latest progress in design\, synthesis and transplant syntheti
 c chromosomes and its applications. Finally\, I will also discuss the prog
 ress of developing biocontainment strategies for synthetic genomes.\nSpeak
 ers:\nProf Patrick Cai (University of Manchester)
LOCATION:Medical Sciences Teaching Centre (Lecture Theatre)\, off South Pa
 rks Road OX1 3PL
TZID:Europe/London
URL:https://talks.ox.ac.uk/talks/id/f5f91058-c9f0-4d81-b649-3de136b431af/
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DESCRIPTION:Talk:Engineering and Safeguarding Synthetic Genomes - Prof Pat
 rick Cai (University of Manchester)
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