SLM-based methods for 3D control and imaging in the brain
Recording neuronal activity throughout the brain with high temporal and spatial resolution may be a critical step in understanding how the brain works. Task-based approaches allow intelligent trade-offs between resolution, speed, and signal. I will describe projective two-photon imaging methods that leverage the spatiotemperal sparseness of neural activity and use holographic multiplexing and statistical source separation to create capable platforms for high performance imaging with single cell resolution. Similar holographic platforms can also be used to activate ensembles of neurons with single cell precision, and I will describe recent efforts to improve targeting and control in awake behaving animals.
Date: 19 June 2019, 12:00 (Wednesday, 8th week, Trinity 2019)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Small Lecture Theatre
Speaker: Darcy Peterka (Columbia University)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organiser: Dr Adam Packer (University of Oxford)
Organiser contact email address: adam.packer@dpag.ox.ac.uk
Host: Dr Adam Packer (University of Oxford)
Part of: Neuroscience Theme Guest Speakers (DPAG)
Booking required?: Not required
Audience: Members of the University only
Editor: Talitha Smith