The genetics of reproductive behaviour and relationship amongst 36 reproductive traits

For our next talk, in the BDI/CHG (gen)omics Seminar series, we will be hearing from Prof Melinda Mills, Professor of Demography & Population Health, Director Demographic Science Unit, NDPH, University of Oxford. We’re delighted to host Prof Mills in what promises to be a great talk!

Date: Tuesday 14 May
Time: 9:30 am – 10:30 am
Talk title: The genetics of reproductive behaviour and relationship amongst 36 reproductive traits
Location: Big Data Institute Seminar Room 1

Abstract: Substantial shifts in reproduction and reproductive behaviour have taken place in the last decades in many industrialized countries including earlier age at menarche, advanced age at childbearing, rising childlessness and a lower number of children. As reproduction shifts to later ages, genetic factors may become increasingly important. This talk describes the main findings of recent GWASs of reproductive behaviour (age at first birth, number of children), and their relationship to health and externalising traits. It then links these to a review of 36 reproductive traits of both men and women, examining reproductive behavior, reproductive lifespan and aging, infertility and hormonal concentration. Using the GWAS Catalog as a basis, from 116 relevant studies 2009-2023, we isolate 29 genes that harbour association signals for four or more reproductive traits.

Melinda Mills, MBE, Directs the Leverhulme Centre for Demographic Science and Demographic Science Unit at NDPH, University of Oxford and Nuffield College. She currently also holds a related ERC Advanced Grant, UKRI grant on intergenerational transmission and EU horizon grant linking geospatial indicators to individual level data.
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All members of the University are welcome to join, please let reception at BDI know you’re here for the seminar and sign-in. We hope you can join us!

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As a reminder, the (gen)omics seminar series runs every other Tuesday morning and is intended to increase interaction between individuals working in genomics across Oxford. We encourage in-person attendance where possible. There is time for discussion over, tea, coffee and pastries after the talks.

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