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'Deciphering the dialog between gut epithelial cells and mononuclear phagocytes' by Dr Ana-Maria Lennon-Dumenil
This seminar is open to members of the University of Oxford only. Please register with your University of Oxford email to ensure a successful registration. Registration is at: https://medsci.zoom.us/meeting/register/tJ0tcempqj0uEtFyn0bUrtwZhP8hpdDEW5Lt
Within tissues, dendritic cells constitute a complex cell population composed of distinct subsets that can exhibit different activation states and functions. How tissue-specific cues orchestrate dendritic cell diversification remains elusive. In the first part of my seminar, I will discuss unpublished results showing that, by reaching distinct sub-tissular niches within the gut, dendritic cells can exist as immature and mature cells, revealing a novel mechanism of dendritic cell functional diversification. In the second part of my seminar, I will present data highlighting the essential role of macrophages in protecting colonic epithelial cells from being poisoned by fungi toxins. I will discuss the implications of these findings on colon inflammation and cancer.
Date:
15 November 2021, 12:00
Venue:
Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details:
This seminar is open to members of the University of Oxford only. Please register with your University of Oxford email to ensure a successful registration. Registration is at: https://medsci.zoom.us/meeting/register/tJ0tcempqj0uEtFyn0bUrtwZhP8hpdDEW5Lt
Speaker:
Dr Ana-Maria Lennon-Dumenil (Curie Institute)
Organising department:
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers:
Dr Jelena Bezbradica (The Kennedy Institute of Rheumatology),
Jennifer Pope (Kennedy Institute of Rheumatology),
Professor Irina Udalova (Kennedy Institute of Rheumatology)
Organiser contact email address:
reception@kennedy.ox.ac.uk
Host:
Dr Audrey Gerard (The Kennedy Institute of Rheumatology)
Part of:
Kennedy Institute Seminars
Booking required?:
Required
Booking url:
https://medsci.zoom.us/meeting/register/tJ0tcempqj0uEtFyn0bUrtwZhP8hpdDEW5Lt
Audience:
Members of the University only
Editors:
Jennifer Pope,
Ellen Mobbs
