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*CANCELLED* The Role of DOCK8 in B cell Immune Function
Status: This talk is in preparation - details may change
Status: This talk has been cancelled
This talk has been cancelled. Apologies for any inconvenience,
The DOCK8 Immunodeficiency Syndrome is characterised by a failure to generate long-term T cell dependent protective immunity, associated with absent affinity maturation. Our findings suggest that the absence of DOCK8 causesdefects downstream of the B cell receptor, which result in a failure of B-T cross-talk when antigen is limiting. These effects are associated with reduced B cell survival, which is amplified in the germinal centre.
Date:
16 March 2020, 12:00
Venue:
Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details:
Bernard Sunley Lecture Theatre
Speaker:
Professor Richard Cornall (University of Oxford)
Organising department:
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers:
Jennifer Pope (Kennedy Institute of Rheumatology),
Professor Irina Udalova (Kennedy Institute of Rheumatology)
Organiser contact email address:
jennifer.pope@kennedy.ox.ac.uk
Host:
Professor Fiona Powrie (Kennedy Institute of Rheumatlogy)
Part of:
Kennedy Institute Seminars
Booking required?:
Not required
Audience:
Public
Editor:
Jennifer Pope
