Coping with mechanical stress: tissue dynamics in development and repair
During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how differential growth rates can generate precise folds in tissues. We will also discuss how tissues respond to mechanical perturbations, such as stretching or wounding, by altering their actomyosin contractile structures, to change tissue dynamics, and thus preserve tissue shape and patterning. We combine genetics, biophysics and computational modelling to study these processes.
Date:
27 May 2022, 14:00 (Friday, 5th week, Trinity 2022)
Venue:
Mathematical Institute, Woodstock Road OX2 6GG
Venue Details:
L6
Speaker:
Prof Yanlan Mao (UCL)
Organising department:
Mathematical Institute
Organiser:
Sara Jolliffe (University of Oxford)
Organiser contact email address:
sara.jolliffe@maths.ox.ac.uk
Host:
Dr Ruth Baker (University of Oxford)
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Sara Jolliffe
