Manj’s research seeks to improve our understanding of genomic diversity and the development of and susceptibility to complex diseases by integrating population genetics, epidemiology and genomic wide technologies. His research is focused on low and middle income countries and particularly those in Africa and South-East Asia. He led the development and delivery of the African Genome Variation Project – a major resource that provides insights into population genome diversity in Africa and is engaged in a programme of work to study ancient DNA and indigenous populations groups. He established and co-directs the African Partnership for Chronic Disease Research (APCDR), an international network of scientists committed to strengthening research capacity and undertaking chronic disease research in Africa. Alongside this he is the co-director of the Ugandan Medical Informatics Centre (UMIC) an integrated data centre providing computational resources to African institutions across the region.