Aspergillus infection and inflammation in Cystic Fibrosis
There is no virtual option for this seminar.
Cystic fibrosis (CF)is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and is the most common inherited life-limiting disease in North European people. Next to epithelial cells, CFTR expression has been demonstrated in cells of the innate and adaptive immune system and has shown to be critical for normal function. Approximately 60% of CF patients are infected with Aspergillus fumigatus, and its presence has been associated with accelerated lung function decline. Our work is focussing on the interaction between A. fumigatus and CF epithelial and immune cells with an aim to prevent lung damage caused by A. fumigatus in the airways.
Date: 25 September 2023, 12:00 (Monday, -1st week, Michaelmas 2023)
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: Lecture Theatre
Speaker: Prof Adilia Warris (University of Exeter)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers: Doris Chan (Kennedy Institute of Rheumatology), Jo Silva (NDORMS)
Organiser contact email address:
Host: Dr Jethro Johnson (The Kennedy Institute of Rheumatology)
Part of: Kennedy Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Doris Chan