Silicon Biosystems Seminar: DEPArray™ Digital Sorting to Resolve Heterogeneity on Low Input and Low Cellularity FFPE Tumors and Circulating Tumor Cells
DEPArray™ is the only sorting technology capable of isolating, through a semiconductor controlled microfluidic chip, 100% pure single or pooled cells. Single Circulating Tumor Cells can be isolated from enriched blood, pools of pure Tumor, EMT, TILs and Stromal cells can be isolated from disaggregated FFPE tissue blocks, as well as live cells can be isolated from fresh tumor tissue.

NGS Results show how interpretation of underlying genetic alterations becomes far clearer on samples transformed into collections of pure or single cells, not only improving the detection of Somatic Mutations, but enabling highly informative Copy Number Aberration analysis on the pure cell populations.

During the seminar we will present the principles of operation of the technology, testing and validation of the accuracy of the method with NGS panels and Whole Exome Sequencing, applications in the area of single CTC genetic analysis and FFPE tumor tissues.
Date: 17 November 2016, 12:00 (Thursday, 6th week, Michaelmas 2016)
Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details: Seminar Rooms A & B
Speaker: Raimo Tanzi (Silicon Biosystems)
Organising department: Wellcome Trust Centre for Human Genetics
Organisers: Ana-Maria Lovrich (University of Oxford), Susan Wilson (University of Oxford, Wellcome Trust Centre for Human Genetics)
Organiser contact email address:
Host: Dr Christine Blancher (University of Oxford)
Booking required?: Recommended
Booking url:
Audience: Public
Editor: Ana-Maria Lovrich