Oxford Events, the new replacement for OxTalks, will launch on 16th March. The two-week OxTalks freeze period starts on Monday 2nd March. During this time, there will be no facility to publish or edit events. The existing OxTalks site will remain available to view during this period. Once Oxford Events launches, you will need a Halo login to submit events. Full details are available on the Staff Gateway.
Neisseria meningitidis is a major cause of meningitis and sepsis worldwide. Why some individuals are more susceptible than others to meningococcal disease is not fully understood but individuals with defects in the terminal complement pathway are at higher risk of developing meningococcal disease. Genome wide association studies have identified polymorphisms in factor H and factor H related protein-3, which are linked with susceptibility to meningococcal disease. Here we propose a mechanism whereby competition between these two proteins for a single molecule on the bacterial surface, governed by the relative serum levels of both proteins can influence host susceptibility to meningococcal disease.
