On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
Beta2 glycoprotein I (β2GPI) is an abundant plasma protein composed of 5 domains. The C-terminal disulphide bond is susceptible to cleavage by oxidoreductases. Certain biological functions of β2GPI depend on the redox form of the molecule. Nitric oxide metabolism has been shown to be disrupted in APS patients. We found that nitration of β2GPI occurs in-vivo and in-vitro in patients with APS and SLE and the nitrated form of the molecule alters its biological function. A novel assay was developed to quantify nitrated β2GPI levels. These were raised in patients with autoimmune disease compared to healthy and clinical event controls.
