Targeting Micrometastases for the Treatment of Ovarian Cancer

Unlike many other solid tumours, ovarian cancer seldom spreads outside the abdominal cavity. The most common cause of death is malnutrition secondary to intestinal obstruction because of abdominal metastasis. Understanding the key mechanisms involved in driving abdominal metastases is important for the development of novel strategies to prevent metastasis. In this talk, Dr. Ahmed will present his group’s recent work on enhancing chemotherapy response and preventing ovarian cancer metastasis as well as his ongoing work on monitoring the evolution of micrometastasis on a genome-wide scale.