“Manipulating epigenetic regulators to enable immune checkpoint blockade”

Dr Yang Shi is a Professor of Cell Biology at Harvard Medical School and a noted leader in the field of histone demethylases. He discovered and characterized LSD1, the first histone demethylase to be identified, and has made key contributions to the understanding of epigenetic modifications, gene regulation and diseases such as X-linked mental retardation and cancer. He was elected to the American Academy of Arts and Sciences in 2016.