Multiple roads to the heart and head muscles
Our research focuses on understanding mammalian organ development, with a focus on the development of the heart and head muscles, by studying mouse gastrulation. We identify multipotent progenitors expressing Mesp1 during this phase, which contribute to both muscle types. Investigating their migration, we’ve found distinct signaling landscapes and identified essential effectors influencing progenitor migration. Additionally, we’re using gastruloids, an in vitro model mimicking gastrulation, to study cardiac and skeletal muscle development, highlighting their potential for investigating congenital diseases affecting cell lineages.
Date: 12 April 2024, 15:00 (Friday, -1st week, Trinity 2024)
Venue: IMS-Tetsuya Nakamura Building, Roosevelt Dr, Headington OX3 7TY
Venue Details: Seminar Rooms 1&2
Speaker: Dr Fabienne Lescroart (Aix-Marseille Université)
Organising department: Medical Sciences Division
Host: Dr Nancy Stathopoulou (University of Oxford)
Booking required?: Recommended
Booking url:
Audience: Members of the University only
Editor: Amanda Nicolle