Regulation of claudin-5 at the blood brain barrier in health and disease
This talk will focus on the critical role played by claudin-5 at the blood-brain barrier (BBB). Claudin-5 is the most enriched tight junction component at the BBB and its dysregulation has been implicated in a range of neurological and neuropsychiatric disorders. Here, the focus will be on understanding how and why claudin-5 becomes disrupted at the BBB. The talk will bring in both pre-clinical and clinical research based approaches to understanding regulation of the BBB in health and disease.
Date: 8 November 2024, 13:00
Venue: Sherrington Library, off Parks Road OX1 3PT
Venue Details: Sherrington Building
Speaker: Professor Matthew Campbell (Trinity College, Dublin)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organisers: Dr Mootaz Salman (DPAG, University of Oxford), Associate Professor Samira Lakhal-Littleton (DPAG, University of Oxford)
Organiser contact email address: events@dpag.ox.ac.uk
Host: Dr Mootaz Salman (DPAG, University of Oxford)
Part of: DPAG Head of Department Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Hannah Simm