Multiomic analysis of the human gut microbiome in autoimmune disease
Special Visiting Scientist Seminar
The microbial residents of the human gut have profound effects on the development and functioning of the immune system. Due to the complex nature of human-microbe interactions, multiomic analyses in which the genes and functional outputs of microbes and host are analysed together, permit greater understanding of the etiology of autoimmune disorders.In this talk, I will review current methods for multiomic microbiome human population studies, showing examples of host and microbial molecular profiles used to understand mechanisms of inflammation in the gut.
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Kevin Bonham received a Bachelor of Science in Biochemistry and Cell Biology from the University of California, San Diego, and obtained his PhD in Immunology from Harvard University, where he studied the cell biology of macrophages and the biochemistry of toll-like receptor signalling. His postdoctoral work has focused on microbial genomics in multispecies communities such as cheese rinds and the human gut, as well as STEM education and the gender gap in computational biology.
Date: 16 January 2018, 12:00
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: Bernard Sunley Lecture Theatre
Speaker: Dr Kevin Bonham (The Huttenhower Lab )
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers: Laura Sánchez Lazo (Kennedy Institute of Rheumatology), Professor Irina Udalova (Kennedy Institute of Rheumatology)
Host: Professor Fiona Powrie (Kennedy Institute of Rheumatology)
Booking required?: Not required
Audience: Members of the University only
Editor: Laura Sanchez Lazo