Biophysical characterization of G6b-B: advancing the field of ITIM receptors

Bio: Prof. Senis will present data pertaining to the type I TM IgSF ITIM receptor, G6b-B. This receptor contributes to fine tuning platelet responses to vascular injury, and also performs a vital and non-redundant role in platelet turnover. Prof. Senis would be really interested in working with the SGC and would like to meet with anyone that can help in the crystallography of G6b-B, which has so far been a little… challenging, as well as anyone that might be able to help with identifying small molecules that inhibit or modulate G6b-B activity to help clarify the role of this ITIM receptor in platelet function.