Developing the Flatworm Macrostomum Lignano as a Model Organism for Research on Stem Cells, Regeneration and Ageing
Macrostomum lignano is a free-living flatworm with high regeneration capacity. Due to its small size, short generation time, amenability to genetic manipulation and easy maintenance in laboratory conditions, M. lignano is a potent invertebrate experimental model for stem cell research. For the last several years my laboratory has been developing molecular biology resources and tools for this model organism. M. lignano genome and transcriptome assembly and annotation will be presented, discovery of stem cell markers and development of methods for transgenesis described, and gene expression changes during ageing and regeneration in M. lignano discussed.
Date: 26 February 2018, 13:00 (Monday, 7th week, Hilary 2018)
Venue: University Museum of Natural History, Parks Road OX1 3PW
Venue Details: Lecture Theatre
Speaker: Professor Eugene Berezikov (European Institute for the Biology of Ageing)
Organising department: Department of Zoology
Organisers: Dr Roberto Salguero-Gomez (University of Oxford), Professor Aziz Aboobaker (Dept Zoology, University of Oxford)
Organiser contact email address: administrator.pa@zoo.ox.ac.uk
Host: Dr Roberto Salguero-Gomez (University of Oxford)
Topics: Stem cells, Aging, Regeneration (Biology), Molecular biology
Booking required?: Not required
Audience: Public
Editor: Kirsty Jackson