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Pharmacogenetic and pharmaco-epidemiological approaches to synergistically boost precision pharmacotherapy in psychiatry
Psychiatry is in need of tools to improve personalised treatment given the high rates of adverse drug reactions and generally low remission rates. Here, I discuss how pharmaco-genetics approaches have elucidated that some treatment outcomes in severe psychiatric disorders are associated with polygenic risk profiles. I also give examples of real-world epidemiological approches that have potential to curtail risks of psychotropic mediation use and improve response rates. Finally, I summarise some of the insights Mendelian Randomisation studies conducted at my lab have provided. Overall, the aim of the talk is to critically appraise the hypothesis that more personalised prescribing is possible in psychiatry. I look forward to critical thoughts, suggestions, lively discussions, and possible future collaborations.
zoom.us/j/98643323773?pwd=bL0TW4vweAlQzIlL5VEFHKYiEaVYPl.1
Meeting ID: 986 4332 3773
Passcode: 758174
Date:
3 December 2024, 9:30
Venue:
Department of Psychiatry, Headington OX3 7JX
Venue Details:
Seminar Room
Speaker:
Professor Jurjen Luykx (Maastricht University)
Organising department:
Department of Psychiatry
Organiser:
Rania Elgarf (Department of Psychiatry, University of Oxford)
Organiser contact email address:
rania.elgarf@psych.ox.ac.uk
Host:
Professor Belinda Lennox (Associate Professor and Clinical Senior Lecturer, University Department of Psychiatry, Oxford)
Part of:
Psychiatry Seminar Series
Booking required?:
Not required
Audience:
Public
Editor:
Rania Elgarf
