Race against resistance: Improving diagnostics to address AMR
Antimicrobial resistance (AMR) poses a significant threat to modern medicine, jeopardising the advances achieved over recent decades. Without effective interventions, AMR-related deaths are projected to exceed all other causes by 2050. High performing diagnostics are key to understanding and addressing this problem.
In my presentation, I will discuss two innovative solutions developed in collaboration with colleagues at IBMS. First, we are employing Raman spectroscopy for the rapid identification of disease-causing bacteria and determine their sensitivity to antibiotics. This technique promises to enhance the accuracy of diagnosis and expedite appropriate treatment decisions. The ambition is to transition to a culture-free new standard for microbiology diagnostics that generates insight on a single cell level.
Second, I will introduce a Loop-Mediated Isothermal Amplification (LAMP) method, a user-friendly amplification technique that requires minimal equipment. We have successfully developed assays targeting the most common sexually transmitted infections (STIs) using this approach.
I will present data demonstrating the performance of these assays and explore their potential integration into routine clinical practice, ultimately aiming to improve patient outcomes in the face of rising AMR.
Date: 20 November 2024, 11:45 (Wednesday, 6th week, Michaelmas 2024)
Venue: John Radcliffe Academic, Headington OX3 9DU
Venue Details: NDCLS Seminar Room, Level 4 Academic Block, access via stairs near Cairns library
Speaker: Dr Monique Andersson (University of Oxford)
Organising department: Radcliffe Department of Medicine
Organiser: Dr Stephanie Jones (University of Oxford)
Organiser contact email address: stephanie.jones@ndcls.ox.ac.uk
Host: Prof Deborah Gill (University of Oxford )
Booking required?: Not required
Cost: None
Audience: Members of the University only
Editor: Stephanie Jones