OxTalks will soon be transitioning to Oxford Events (full details are available on the Staff Gateway). A two-week publishing freeze is expected to start before the end of Hilary Term to allow all future events to be migrated to the new platform. During this period, you will not be able to submit or edit events on OxTalks. The exact freeze dates will be confirmed on the Staff Gateway and via email to identified OxTalks users.
If you have any questions, please contact halo@digital.ox.ac.uk
Chair: Dr Laurence Hunt
Abstract: Emotions and social interactions colour our lives and shape our behaviours. Using animal models and engineered manipulations, we aim to understand how social and emotional behaviours are encoded in the brain, focusing on the neural circuits underlying dominance hierarchy and depression. This lecture will highlight recent discoveries on the interplay between winning history and prefrontal circuit activities; the impact of social status loss on depression; and, finally, how ketamine tames depression by blocking burst firing in the brain’s anti-reward centre, and how glia-neuron interaction plays a surprising role in this process. I will also present our recent work on the mechanism underlying the sustained antidepressant activity of ketamine and its brain region specificity.
