A Point-of-Care Assay to Detect Antimalarial Drugs from Finger Stick Blood Samples
Refreshments are provided, please arrive in good time.
The goal of this research is to develop a low-cost, field-based test to detect several slow-clearing ACT drug compounds from unprocessed fingerstick blood samples. The test will detect drugs through the binding of target-specific aptamers or antibodies and provide a colorimetric readout of drug levels. The ability to detect small molecule antimalarial drugs in a patient’s blood at point-of-care would enable healthcare workers to identify a previous treatment failure and adjust the patient’s new treatment to improve its efficacy and thus reduce the spread of resistant parasites. A simple assay to detect these drugs in patient samples would also facilitate real-time mapping of drug usage and compliance.
Date: 22 September 2016, 12:30 (Thursday, -2nd week, Michaelmas 2016)
Venue: NDM Building, Headington OX3 7FZ
Venue Details: Basement Seminar Room
Speaker: Erin Coonahan (NIH Oxford Scholar)
Organising department: Centre for Tropical Medicine and Global Health
Organiser: Georgina Humphreys (WWARN, University of Oxford)
Organiser contact email address: georgina.humphreys@wwarn.org
Host: Georgina Humphreys (WWARN, University of Oxford)
Part of: Tropical Medicine Global Health Seminars
Topics:
Booking required?: Not required
Audience: Members of the University only
Editor: Francois Van Loggerenberg