Intravital microscopy of tumour vasculature – recent developments

Tumour vasculature plays a fundamental role in the growth and response of tumours to therapy. Intravital microscopy using different window chamber techniques can provide an insight into the mechanisms behind the response of tumour vasculature to treatment. This talk will summarize the last developments in Muschel group regarding imaging of tumour vasculature in the VeCadherin-Cre-ERT2-tdTomato mouse model, our efforts in improving the imaging process and preparation for irradiation of tumours with Small Animal Radiation Research Platform (SARRP).