Studying the anatomical organization of the human hippocampal system using high-field MRI
Please note change of time! This talk starts at 1pm.
TBATeams link: www.win.ox.ac.uk/events/win-seminar-7may

Animal tract-tracing studies provided critical insights into the organizational principles of the hippocampal system, thus defining the anatomical constraints within which animal mnemonic functions operate. However, no clear framework defining the anatomical organization of the human hippocampal system exists. This gap in knowledge originates in notoriously low MRI data quality in the human medial temporal lobe and in group-level blurring of idiosyncratic anatomy between adjacent brain regions comprising the medial temporal lobe. In this talk, I will present our recent data, which overcame these longstanding challenges and allowed us to explore in detail the cortical networks associated with the human medial temporal lobe, and to examine the intrinsic organization of the hippocampal-entorhinal system with unprecedented anatomical precision. Our results point to biologically meaningful and previously unknown organizational principles of the human hippocampal system. These findings facilitate the study of the evolutionary trajectory of the hippocampal connectivity and function across species, and prompt a reformulation of the neuroanatomical basis of episodic memory.
Date: 7 May 2025, 13:00
Venue: FMRIB Centre, Headington OX3 9DU
Venue Details: Cowey Room, FMRIB Annexe
Speaker: Daniel Reznik (Max Planck Institute for Human Cognitive & Brain Sciences)
Organising department: Nuffield Department of Clinical Neurosciences
Organisers: Stuart Clare (University of Oxford), Dr Nima Khalighinejad (University of Oxford)
Organiser contact email address: admin@win.ox.ac.uk
Part of: OxCIN Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Iske Bakker