What determines oncogenic competence?
This is a hybrid event - with the speaker attending in-person and viewable on Teams.
Oncogenes are not able to initiate tumours in all cellular contexts, a phenomenon referred to as oncogenic competence. Such competence depends on both cell-intrinsic programs (i.e. developmental and epigenetic state) as well as cell-extrinsic influences from the TME. To study this, we have developed zebrafish and human pluripotent stem cell models of melanoma. In the talk, I will discuss how convergence of intrinsic and extrinsic programs determines the likelihood of oncogenic transformation.
Date:
1 February 2024, 12:00 (Thursday, 3rd week, Hilary 2024)
Venue:
MRC Weatherall Institute of Molecular Medicine, Headington OX3 9DS
Venue Details:
Seminar Room
Speaker:
Professor Richard White (Oxford Ludwig Institute)
Organising department:
MRC Weatherall Institute of Molecular Medicine
Organiser:
Yasmine Saito (Weatherall Institute, University of Oxford)
Organiser contact email address:
yasmine.saito@imm.ox.ac.uk
Host:
Dr Ewa Gogola (University of Oxford)
Booking required?:
Recommended
Booking email:
seminar.admin@imm.ox.ac.uk
Audience:
Members of the University only
Editor:
Yasmine Saito
