From Molecules to Mouthfeel: How Chemistry Drives Oral Care R&D in Industry
A former Oxford Visiting Student (Chemistry) brings case studies from toothbrush and dentifrice
development in a global consumer-goods company, highlighting how the various scientific
disciplines interact to deliver innovative products.

The talk introduces the underlying principles of Oral Health and its maintenance via effective
plaque removal by mechanical and chemical means. It bridges science with the consumer world
e.g. via clinical efficacy and product safety considerations (Mark, 2021).

Mechanical plaque removal, usually by brushing, provides different levels of cleanliness and Oral
Health improvement. Plaque reduction and gingival health outcomes are consistently better
when oscillating rotating electrical toothbrushes are used (Grender, 2020). Further improvements
can be made with additional technical features e.g. pressure sensors (Janusz, 2008) or position
tracking (Thurnay, 2022).

Chemistry adds significantly to the cleaning efficacy. Specifically stannous fluoride (SnF2) has a
higher impact vs. other formulation. It is a well-researched active ingredient in dentifrice
formulations. Numerous clinical studies and systematic reviews support its broad efficacy
(Biesbrock, 2019).

The talk also provides insights into industrial R&D and career opportunities
Date: 16 March 2026, 14:00
Venue: Inorganic Chemistry Laboratory, South Parks Road OX1 3QR
Venue Details: Lecture Theatre
Speaker: Dr Erwin P. Mark (Procter & Gamble)
Organising department: Inorganic Chemistry Laboratory
Organiser: Michail Stamatakis (Chemistry, University of Oxford)
Part of: Inorganic Chemistry Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Katherine Hayes