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The story behind next generation DNA sequencing
In person only
The capability to image single molecules has revolutionised biology. I will explain how these methods work and how we are currently applying them to study the molecular basis of neurodegenerative disease. Lastly I will describe how our early single molecule work on DNA polymerase led to the development of next generation DNA sequencing, now widely used, and the lessons that can be learnt from this experience.
Professor Sir David Klenerman is a distinguished physical chemist at the University of Cambridge, renowned for co-inventing Illumina next-generation DNA sequencing. After earning his PhD at Cambridge and becoming a Fulbright scholar at Stanford, he worked at BP Research before joining Cambridge in 1994. Prof Klenerman transformed genomics by enabling fast, low-cost DNA sequencing, for which he was knighted in 2019. He is a Fellow of the Royal Society and Academy of Medical sciences. His current work focus on immune recognition and on neurodegenerative diseases, through the UK DRI at Cambridge. Prof Klenerman has been awarded the Royal Medal of the Royal Society, Millennium Technology Prize (2020), the Breakthrough Prize in Life Sciences (2022), and the Canada Gairdner International Award and Novo Nordisk Prize (2024).
Date:
28 May 2026, 12:00
Venue:
MRC Weatherall Institute of Molecular Medicine, Headington OX3 9DS
Venue Details:
Seminar Room
Speaker:
Professor Sir David Klenerman FRS (Yusuf Hamied Department of Chemistry, Cambridge University)
Organising department:
MRC Weatherall Institute of Molecular Medicine
Organiser:
Yasmine Saito (Weatherall Institute, University of Oxford)
Organiser contact email address:
seminar.admin@imm.ox.ac.uk
Host:
Prof Simon Davis (MRC Weatherall Institute of Molecular Medicine, University of Oxford)
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Yasmine Saito
