‘Bacterial stress responses and surface adhesion in shear flow’
For over 100 years, bacteria have been studied in simplified laboratory settings. While reductionist experimental systems provided great mechanistic insight, they lack key aspects of natural systems such as fluid flow. Thus, we now have an opportunity to solve outstanding problems in microbiology by implementing experimental systems that more precisely model natural conditions. My research group combines traditional molecular biology approaches with microfluidic technology to examine how host-relevant shear flow influences the human pathogen Pseudomonas aeruginosa. Specifically, we explore how flow impacts how bacteria respond to stress and stick to surfaces.
Date: 13 March 2024, 14:00 (Wednesday, 9th week, Hilary 2024)
Venue: Dorothy Crowfoot Hodgkin Building, off South Parks Road OX1 3QU
Venue Details: Seminar Room 1, 20-026
Speaker: Professor Joe Sanfilippo (School of Molecular & Cellular Biology, University of Illinois Urbana-Champaign)
Organising department: Department of Biochemistry
Organisers: Professor Achillefs Kapanidis (University of Oxford), Stephan Uphoff (University of Oxford)
Organiser contact email address: stephan.uphoff@bioch.ox.ac.uk
Hosts: Professor Achillefs Kapanidis (University of Oxford), Stephan Uphoff (University of Oxford)
Part of: Seminar
Booking required?: Not required
Audience: Members of the University only
Editor: Sarah-Jane Scard