OxTalks is Changing
OxTalks will soon be transitioning to Oxford Events (full details are available on the Staff Gateway). A two-week publishing freeze is expected in early Hilary to allow all events to be migrated to the new platform. During this period, you will not be able to submit or edit events on OxTalks. The exact freeze dates will be confirmed as soon as possible.
If you have any questions, please contact halo@digital.ox.ac.uk
Moving Folded Proteins Across Membranes: a Tale of Two Transporters
Proteins are generally assumed to be transported across membranes in an unfolded state. However, it is becoming increasingly apparent that there are also transporters dedicated to moving folded proteins through membranes. We have identified two such systems in bacteria. The Tat (twin-arginine translocation) system is found in the bacterial cytoplasmic membrane and conserved in some eukaryotic organelles. The Type 9 Secretion System is found in the outer membrane of bacteria from the Bacteroidetes superphylum. Both transport systems are essential virulence determinants in human pathogens. I will describe our latest data on these transport systems and show that they transport folded proteins by very different mechanisms.
Date:
4 October 2023, 11:00
Venue:
Sir William Dunn School of Pathology, South Parks Road OX1 3RE
Venue Details:
EPA Seminar Room
Speaker:
Professor Ben Berks (Department of Biochemistry, University of Oxford)
Organising department:
Sir William Dunn School of Pathology
Organiser:
Jo Peel (University of Oxford, Sir William Dunn School of Pathology)
Organiser contact email address:
jo.peel@path.ox.ac.uk
Host:
Professor Matthew Freeman (Sir William Dunn School of Pathology, University of Oxford)
Part of:
Dunn School of Pathology Research Seminars
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Jo Peel
