OxTalks is Changing
OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The 4th Dimension of Gene Regulatory Networks: TIME
Please see booking link for Zoom details
Rapid reprogramming of transcriptional networks enables cells to dynamically adapt to a changing environment. However, most gene regulatory networks (GRNs) are captured and modeled as a static web of interactions. To fill this gap, Gloria and colleagues’ studies exploit TIME – the relatively unexplored dimension of GRNs – to uncover the temporal transcriptional logic that underlies dynamic nitrogen (N) signalling in plants. Because causality moves forward in time, fine-scale time-series data of genome-wide N-responses enables us to infer and validate GRN models that are able to predict TF -> target relationships in out-of-sample data – the ultimate goal of systems biology. More broadly, the time-based approaches we develop and deploy can be applied to uncover the temporal transcriptional logic for any signalling response system in biology, agriculture or medicine.
Date:
16 June 2022, 15:00
Venue:
Zoom
Speaker:
Dr Gloria Coruzzi (New York University)
Host:
Jane Langdale (University of Oxford)
Booking required?:
Not required
Booking url:
https://docs.google.com/spreadsheets/d/1Z6P6wRKijsDgM24XE-YsrUsj1X7BgzOIhkFU8zK6mGk/edit#gid=1242014929
Audience:
Members of the University only
Editor:
Monica Gujral
