Multiscale and multiomic kidney profiling to define glomerular disease signatures
Chronic kidney disease (CKD) is common, with a heavy health and economic burden, and prevalence is rising globally. Limited understanding of the cellular basis of many glomerular kidney diseases is a major barrier to the development of targeted, more effective treatments. To address this, our group seeks to transform renal pathology, using spatial and single cell transcriptomics and proteomics in renal biopsy tissue to define patterns of disease, in order to better stratify patients, predict treatment response and prioritise new therapeutic targets, for validation in model systems. Our work includes interdisciplinary collaborations to develop new methods to leverage high quality information from high resolution spatial data.
Date: 15 October 2024, 9:30 (Tuesday, 1st week, Michaelmas 2024)
Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details: Room A+B
Speaker: Dr Katherine Bull
Organising department: CAMS Oxford Institute
Organisers: Dr Ricardo Fernandes (CAMS Oxford Institute), Dr Dannielle Wellington (CAMS Oxford Institute), Mimie Szyk (CAMS Oxford Institute)
Part of: CAMS Oxford Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Mimie Szyk