Modelling breast cancer using human tumour explants

Professor Caldas holds the Chair of Cancer Medicine at the University of Cambridge since 2002. He heads the Breast Cancer Functional Genomics Laboratory at the Cancer Research UK Cambridge Research Institute. He is an Honorary Consultant Medical Oncologist at Addenbrooke’s Hospital, and Director of the Breast Cancer Programme at the CRUK Cancer Centre. He is Fellow of the American College of Physicians, the Royal College of Physicians and the Royal College of Pathologists. He has been elected a Fellow of the Academy of the Medical Sciences, a Fellow of the European Academy of Cancer Sciences, and an EMBO Member. In 2016 he received the ESMO Hamilton Fairley Award.
Professor Carlos Caldas is a graduate from the University of Lisbon Medical School and trained in Internal Medicine at UT Southwestern, Dallas and Medical Oncology at Johns Hopkins Hospital, Baltimore. He then completed a research fellowship at the Institute of Cancer Research in London. In 1996 he moved to Cambridge where he has directed a research group working on the genetic alterations underlying human epithelial malignancies, with a particular focus on breast cancer.
His current research focus is in the functional genomics of breast cancer and its biological and clinical implications. His main clinical interest is in breast cancer chemotherapy and novel molecularly targeted therapies. He has published over 300 peer-reviewed papers including in New England Journal of Medicine, Nature, Cell, Nature Genetics, Nature Medicine, Cancer Cell, Science Translational Medicine, PNAS, Cancer Research, Clinical Cancer Research, Journal of Clinical Oncology, Genome Biology, PLOS Biology, PLOS Medicine, Lancet Oncology, Breast Cancer Research and Oncogene.