OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
In humans, fetal survival depends on proper patterning and morphogenesis of the embryo and its accompanying placenta. Abnormal morphogenesis in the embryo underlies developmental abnormalities such as DiGeorge syndrome and Mandibulofacial dysostosis with microcephaly (MFDM), and results in increased morbidity and mortality. We use the mouse model to study the genetic and cellular basis of morphogenesis during the embryonic period; furthermore, the availability of next generation sequencing has enabled the rapid identification of genes associated with developmental abnormalities. The goals of my research program are (1) to use forward genetics to identify the genes responsible for malformations in human and mouse during pregnancy; (2) to use reverse genetics in the mouse model to characterize the cellular pathways regulated by genes implicated in developmental syndromes.
